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Marked first-degree atrioventricular block. A new indication for
Marked first-degree atrioventricular block. A new indication for

... failure (CHF) of various etiologies have generally yielded disappointing results. In some patients conventional DDD pacing causes further deterioration of LV function related to pacing-induced abnormal ventricular depolarization. In patients with 1st degree AV block, conventional DDD pacing abolishe ...
failure of the right ventricle
failure of the right ventricle

... hypothesis is that a local rise of pressure occurred in the pulmonary arteries as a result of spasm or some other unknown factor that left no mark upon the final pathology of the lungs, and that such isolated pulmonary hypertension occasioned hypertrophy and later failure of the right ventricle. A s ...
Silvia Borras - Association for Clinical Genetic Science
Silvia Borras - Association for Clinical Genetic Science

... Spevak PJ, Bluemke DA, Abraham T, Russell SD, Calkins H and Judge DO (2006b). Clinical features of arrhythmogenic right ventricular dysplasia/cardiomyopathy associated with mutations in Plakophilin-2. Circulation, 113:1641-1649 Fontaine G, Frank R, Vedel J, Grosgogeat Y, Cabrol C, Facquet J (1977). ...
Lenient versus Strict Rate Control in Patients with Atrial Fibrillation
Lenient versus Strict Rate Control in Patients with Atrial Fibrillation

... with atrial fibrillation receiving rate-control therapy and in those receiving rhythm-control therapy.2,3 Therefore, rate control has become front-line therapy in the management of atrial fibrillation. The optimal level of heart-rate control, however, is unknown, as is whether strict rate control is ...
I Love My Heart
I Love My Heart

... WEBSITES About the Heart http://www.nhf.org.nz The Heart Foundation is committed to improving heart health by funding vital research, advancing cardiac rehabilitation and promoting healthy lifestyle choices. The website has details of lifestyle choices which improve a healthy heart, facts about diet ...
Document
Document

... – Pericardial friction rub (usually triphasic – ...
Relationship between right ventricular ejection fraction and
Relationship between right ventricular ejection fraction and

... anaerobic threshold was used as our primary parameter of interest. Medication was found to be relatively homogeneously distributed among patients. Thus, although we cannot exclude that these effects distorted existent correlations, we consider it unlikely. This view is strengthened by the consistenc ...
Personality, Disease Severity, and the Risk of Long
Personality, Disease Severity, and the Risk of Long

... patients (1) is unrelated to the severity of cardiac disorder, (2) predicts cardiac events, and (3) is a function of basic personality traits. Methods and Results—Eighty-seven patients with MI (age, 41 to 69 years) with an LVEF of #50% underwent psychological assessment at baseline. Patients and the ...
Surgical Outcome of Congenital Heart Disease Cases: A single Unit
Surgical Outcome of Congenital Heart Disease Cases: A single Unit

... Also TOF patients with large major aorto pulmonary collateral arteries were not taken up. Case selection is very important for any upcoming cardiac surgical unit in a government set up, with limited resources. The aim should be to lay a solid foundation on which one can build a castle in future. Con ...
Saccular aneurysms of left ventricle - Heart
Saccular aneurysms of left ventricle - Heart

acute right ventricular failure
acute right ventricular failure

... sym pathetic dampening and suppression of the renin- angiotensin axis by increasing cGMP). It reduces both preload and afterload, consequently im proving cardiac output without inotropy. Concerns exist over the decreased 30-day survival and its adverse impact on renal function. - In addition the sys ...
Sequential Segmental Analysis of the Heart: A Malformation
Sequential Segmental Analysis of the Heart: A Malformation

... The morphologically right and left ventricles have a constellation of anatomic features which allow each to be recognized by a sonographer. Irrespective of their spatial orientation, apical trabeculations of the morphologically right ventricle are more coarse than that of the left ventricle and ther ...
Contractile function of myocardium and pumping function
Contractile function of myocardium and pumping function

... the pressure decreased. These events become evident as the first moderately negative wave. Thereafter the atrial pressure increases in direct proportion to the amount of blood flowed into the atrii which is recorded as the third positive wave. At the onset of diastole the AV valves open and the blood ...
Phase II Trial of Pertuzumab and Trastuzumab in
Phase II Trial of Pertuzumab and Trastuzumab in

... objective response as best response, respectively. Efficacy analyses were based on the intent-to-treat (or all-treated) population, including all patients who received any study medication. The safety analysis population included all patients who received any pertuzumab and had ⱖ one postbaseline sa ...
Key Terms PDF - QuizOver.com
Key Terms PDF - QuizOver.com

... period of time between the onset of atrial contraction (atrial systole) and ventricular relaxation (ventricular diastole) ...
TCT 27th Annual Scientific Symposium TCT 27th Annual
TCT 27th Annual Scientific Symposium TCT 27th Annual

... was target lesion failure (cardiac death, target vessel MI, or ischaemia-driven target lesion revascularisation) at 1 year. Target lesion failure at 1 year occurred in 7.8% of patients in the Absorb group and in 6.1% of patients in the Xience group (difference, 1.7%; 95% CI, −0.5 to 3.9; p=0.007 for ...
Saccular aneurysms of left ventricle
Saccular aneurysms of left ventricle

... the subject of rare ventricular aneurysms (including both true aneurysm and pseudo-aneurysm formnation) is briefly discussed. In both patients the diagnosis of left ventricular aneurysm was unsuspected on clinical or on radiological grounds until the lesion was shown by selective left ventricular an ...
athology 6020 - Year 2005  Paul Urie, M.D., Ph.D. Dec.
athology 6020 - Year 2005 Paul Urie, M.D., Ph.D. Dec.

... Death is due to ventricular electrical instability (arrhythmia). ...
An echocardiogram, also known as a cardiac ultrasound, is a
An echocardiogram, also known as a cardiac ultrasound, is a

... Many diagnostic tools to evaluate your pet’s heart health are available; each type of diagnostic can tell different things about the heart. Your pet may have had an electrocardiogram (also known as an ECG or an EKG). An ECG shows the electrical currents running through the heart, and may show any ab ...
Lenient versus Strict Rate Control in Patients with Atrial Fibrillation
Lenient versus Strict Rate Control in Patients with Atrial Fibrillation

... with atrial fibrillation receiving rate-control therapy and in those receiving rhythm-control therapy.2,3 Therefore, rate control has become front-line therapy in the management of atrial fibrillation. The optimal level of heart-rate control, however, is unknown, as is whether strict rate control is ...
left ventricular hypertrophy
left ventricular hypertrophy

... the ECG patterns of right and left ventricular ...
1 Metastatic myocardial abscess on the posterior wall of left ventricle
1 Metastatic myocardial abscess on the posterior wall of left ventricle

... reluctant to operate with limited amount of information. Cardiac MRI was obtained, which exhibited a 4.5cm diameter left ventricular posterior wall abscess contained by only a 2mm thin layer of myocardium (Figure 2). The abscess was considered to be in a location suitable for surgical treatment and ...
119 - Coastal West Sussex Formulary
119 - Coastal West Sussex Formulary

... Therefore 115 patients per annum initiated on Entresto® – total drug cost = 115 x £91.60 x12 = £126,408 for first year. This figure would approximately double for the second year as a further 12% of eligible patients were initiated on Entresto®. Anticipated involvement of specialist nurses: Identify ...
atrioventricular_valve_dysplasia
atrioventricular_valve_dysplasia

... • Restricted in accordance with severity of clinical signs ...
Aortic and Mitral Valve Surgery on the Beating Heart is Lowering
Aortic and Mitral Valve Surgery on the Beating Heart is Lowering

... cross clamp time (ischemic time of myocardium). In the last few years a number of different techniques emerged in the field of cardiac surgery, which were directed toward better results in the selected high risk patients or to minimize the deleterious effects of cardiopulmonary bypass (CPB) on the o ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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