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Chapter 20 The Heart
Chapter 20 The Heart

... Pass through ventricular myocardium Fast rate of action potential generation and serve to synchronizes ventricular contraction the contraction of the ventricles starts at the apex so that all blood is forced up and out action potentials spreads from cell to cell via gap junctions all alone the condu ...
Six Heart Healthy Actions
Six Heart Healthy Actions

... Even people who look healthy and free of heart disease can have arrhythmias (abnormal heart rhythms) and be at risk of sudden cardiac arrest (SCA). But those with heart disease are at the highest risk. Reducing heart disease is important to help lower the risk of arrhythmias, stroke and SCA. This Fe ...
Mean Frequency Of Premature Ventricular Complexes As
Mean Frequency Of Premature Ventricular Complexes As

... changes in the frequency of PVCs may be useful indicators of transient destabilization capable of progressing to malignant arrhythmias (45). Since the involvement of PVCs in the genesis of malignant arrhythmias is supported by experimental evidence, it was hypothesized that their suppression could r ...
Gastrointestinal Symptoms from Left
Gastrointestinal Symptoms from Left

... commonly reported adverse events include gastrointestinal (GI) bleeding (GIB), device malfunction, and infections. GIB can result in significant morbidity, and its incidence has been estimated to range between 18–40%.4,5 While GIB remains the most recognized adverse GI event, other complications from ...
Aortic stenosis and CT calcium scoring: is it for - Heart
Aortic stenosis and CT calcium scoring: is it for - Heart

... (subjects in this group were substantially younger than the patients in the trileaflet group). The authors postulate several explanations related to the former: that bicuspid valves may suffer from leaflet fibrosis rather than calcification; that abnormalities in the morphology of the leaflets and valve ...
The Basic Cardiac Exam
The Basic Cardiac Exam

... The Fetal Cardiac Exam….. ...
The Pattern Comparison of Changes of Heart Macro-Structure in the Fowl
The Pattern Comparison of Changes of Heart Macro-Structure in the Fowl

... of age males possessed longer hearts than females and also gross heart weight were heavier in males, as compared to females, at 34 and 48 d of age, but did not differ from females at hatching and 20 day of age. However, these gross findings at 34 and 48 days of age in broiler are adverse with data o ...
Acute myocarditis and pulmonary edema due to scorpion sting
Acute myocarditis and pulmonary edema due to scorpion sting

... included transient mitral regurgitation and LV diastolic function. One mortality case was reported, otherwise the other 8 patients improved gradually over 5-7 days untill complete recovery7 . In our case, which is the first to reported in Qatar, the initial presentation was hypotention, tachycardia ...
Public Summary Document - Word 261 KB
Public Summary Document - Word 261 KB

... The current clinical management algorithm for this patient group is complex thus leading to variability in standard care practices which may contribute to variations in the likelihood of being hospitalised. MSAC agreed on the importance of defining current standard care for this patient population f ...
Resistance training for chronic heart failure patients on beta blocker
Resistance training for chronic heart failure patients on beta blocker

... Background: Resistance training increases the skeletal muscle strength and functional ability of chronic heart failure patients. However, there is limited data regarding the effect of resistance training on the hemodynamic responses and peak oxygen consumption (peak VO2) of chronic heart failure pat ...
Cardiac Pathology_1 - bloodhounds Incorporated
Cardiac Pathology_1 - bloodhounds Incorporated

... stretching of the cardiac myocytes prior to contraction. • Preload, therefore, is related to the sarcomere length. • Preload is also related to the volume of blood in ventricles at the end of diastole – Depends on venous return – Depends on compliance ...
PDF - Circulation
PDF - Circulation

... When angiotensin was infused during IABP and systolic arterial pressure was matched to the level present prior to the institution of balloon pumping, the P/S flow ratio returned to prepumping levels in spite of a marked increase in coronary perfusion pressure (fig. 3). In the patients with AMR, the ...
20-1 Anatomy of the Heart
20-1 Anatomy of the Heart

... o 20-1 Describe the anatomy of the heart, including vascular supply and pericardium structure, and trace the flow of blood through the heart, identifying the major blood vessels, chambers, and heart valves. o 20-2 Explain the events of an action potential in cardiac muscle, indicate the importance o ...
- Wiley Online Library
- Wiley Online Library

... those receiving propofol, P = 0.002. The 1-year follow-up identified two patients who died in the propofol group (one myocardial infarction and one low cardiac output syndrome) and one in the sevoflurane group (myocardial infarction). Conclusion: In this study, patients with coronary artery disease ...
Congestive heart failure: the case for decreased variability as a
Congestive heart failure: the case for decreased variability as a

... contractility with wall thickening and decreased left ventricuhour period was 76 beats per minute, and in whom the heart lar size at end-systole [6]. Heart failure patients often cannot rate only increased to 114 beats per minute with exercise. Figaugment regional wall motion with exercise, and with ...
Sports and cardiology: an explosive cocktail?
Sports and cardiology: an explosive cocktail?

... In case of parietal hypertrophy in a high-level athlete, which of the following proposition(s) is/are in favour of hypertrophic cardiomyopathy A) An isolated dilation of the left atrium B) An asymetrical hypertrophy, mostly in apical C) Interventricular septum hypertrophy > 15 mm D) A higher A mitr ...
The Cardiovascular System: The Heart
The Cardiovascular System: The Heart

... cardiac cells together and allow free passage of ions • Heart muscle behaves as a functional syncytium – (i.e. there is a continuous electrical connection and thus the muscle works together). CM ...
ABSTRACT - Cairo University Scholars
ABSTRACT - Cairo University Scholars

... prognosis in patients with STEMI. (14 ) Identification of optimal strategies for treating these patients is the subject of considerable interest and controversy. Objective: To compare in-hospital, long-term outcomes and LV EF ( 6 months) between complete revascularization(CR) and culprit - only reva ...
Palpitation
Palpitation

... QTU interval in the sinus beats is at least 600 milliseconds. Note TU wave alternans in the first and second complexes. A late premature complex occurring in the downslope of the TU wave initiates an episode of ventricular tachycardia ...
Emergency defibrillation performed by coronary nursing staff: a pilot
Emergency defibrillation performed by coronary nursing staff: a pilot

... prognosis of these patients was changed substantially. In the absence of a doctor, the trained nurse was able to correctly diagnose cardiac arrest, identify the type of arrhythmia and the need to defibrillate, and execute sequential steps to complete defibrillation. In circumstances where one or mor ...
Lecture7 RADIOLOGICAL EXAMINATION OF THE
Lecture7 RADIOLOGICAL EXAMINATION OF THE

... MRI, although they are rarely performed primarily for this purpose. Computed tomography and MRI are particularly useful for assessing thickening of the pericardium, whereas echocardiography is poor in this regard. It is unusual to be able to diagnose a pericardial effusion from the plain chest radio ...
Noncardiac surgery: Postoperative arrhythmias
Noncardiac surgery: Postoperative arrhythmias

... status is the key to management. Although this manuscript is focused on noncardiac surgery, findings from studies conducted after cardiac surgery can be extrapolated (albeit carefully) to these perioperative arrhythmias. Postoperative dysrhythmias are most likely to occur in patients with structural ...
Night-time Bradyarrhythmia in a Patient with Mild Obstructive Sleep
Night-time Bradyarrhythmia in a Patient with Mild Obstructive Sleep

... partly due to an underlying cardiomyopathy, which was aggravated by obstructive apneas. Pathophysiologically, apnea-associated hypoxemia is supposed to cause vagal stimulation, leading to bradycardia, which can be prevented by vagal blockade with atropine.11 Furthermore, a substantial increase in th ...
A Novel Paradigm for Heart Failure With Preserved Ejection Fraction
A Novel Paradigm for Heart Failure With Preserved Ejection Fraction

... specifically altered in heart failure with preserved ejection fraction (HFPEF). A new paradigm for HFPEF development is therefore proposed, which identifies a systemic proinflammatory state induced by comorbidities as the cause of myocardial structural and functional alterations. The new paradigm presu ...
The Heart - Academic Computer Center
The Heart - Academic Computer Center

... The most recent heart sound was caused by… The next heart sound will be caused by… ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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