• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Predictors of Conversion of Recent‐Onset Atrial Fibrillation Treated
Predictors of Conversion of Recent‐Onset Atrial Fibrillation Treated

... reduced systolic function and atrial fibrosis evaluated by magnetic resonance imaging, and they even suggest that persistent atrial fibrillation could generate ventricular fibrosis, leading to depressed contractility.11 This feedback between systolic dysfunction and atrial fibrillation makes atrial ...
heart failure
heart failure

... • It occurs in chronic lung disease, pulmonary valve stenosis. There is reduction of RV output and back pressure on right atrium ( Increased JVP, Liver enlargement, peripheral edema ). 3. Biventricular failure • It affects both ventricle and occurs in dilated Cardiomyopathy, ischemic heart disease, ...
Echocardiographic Evaluation of Orthotopic Heart Transplantation
Echocardiographic Evaluation of Orthotopic Heart Transplantation

... systolic dysfunction and mild pulmonary arterial hypertension were observed in the early postoperative period, but all of them improved gradually overtime. A rise in the RV volume shortly after HTx is an adaptive mechanism to pulmonary hypertension, which is generally present in the recipients due t ...
Digoxin - Webstercare
Digoxin - Webstercare

... The National Heart Foundation of Australia guideline for chronic heart failure recommends ACE inhibitors, unless not tolerated or contraindicated, for all patients with systolic heart failure, whether symptoms are mild, moderate or severe. Diuretics should be used with ACE inhibitors to reduce fluid ...
Atrial fibrillation anticoagulation care in a large urban family
Atrial fibrillation anticoagulation care in a large urban family

... Ontario Ministry of Health for allied care providers such as nurses, nurse practitioners, pharmacists, dietitians, diabetes educators, and social workers (known as a family health team). As part of routine care, patients taking warfarin had the opportunity to see the practice pharmacist or trained n ...
Document
Document

... *SVT with BBB aberration (fixed or functional). ...
I. Blood Chemistries
I. Blood Chemistries

... *WBC represent primary defense against invading infections *This is a total count of all 5 leukocytes: neutrophils, lymphocytes, eosinophils, basophils, and monocytes *Indicates overall degree of bodies response to pathology, but must be evaluated and correlated through differential count *Elevated ...
Name of presentation
Name of presentation

... Sub-Aortic Stenosis Echocardiographic Features • IVS and LVPW thickening • An echodense ridge or band may be seen on the long LVOT view, especially if severe • Aortic valve may be abnormal ...
PPT
PPT

... …then what effect could a QRS duration of 200 ms have on mechanical efficiency and cardiac output? Click for Answer ...
Epicardial Fat Volume in Patients With COPD and Cor Pulmonale
Epicardial Fat Volume in Patients With COPD and Cor Pulmonale

... inflammation is discriminated by oxidative stress, activated inflammatory cells and cytokines and an increase of plasma levels of acute phase proteins. In the meantime, an imbalance between oxidant-antioxidant status could be observed (15). All of these metabolic processes could be effective on EFT. ...
Anginal Pectoris Refractory to Standard Medical Therapy
Anginal Pectoris Refractory to Standard Medical Therapy

... Diastole ...
Therapeutic Hypothermia
Therapeutic Hypothermia

... • European study with 950 patients • Randomized to target temperatures of 33 and 36°C – 460 died – Mortality similar in both groups – Neurological function similar in both groups – Serious adverse events similar in both groups – No difference – This may be we are controlling for fever ...
Tricuspid Valve Annuloplasty Reduces Weaning Time from
Tricuspid Valve Annuloplasty Reduces Weaning Time from

... (Table 2 & 3). Table 4 shows postoperative complications. Patients that did not receive concomitant tricuspid valve annuloplasty had a significantly higher incidence of infection that required prolonged antibiotic treatment (p<0.005). No differences between the two groups were identified regarding i ...
Aortic Stenosis and Comorbidities
Aortic Stenosis and Comorbidities

... - TAVI should only be proposed in patients with severe symptoms that can definitely be attributed to valve disease because of pending questions on safety and valve durability. - TAVI is not recommended for patients who simply refuse surgery on the basis of personal preference. -TAVI is seldom consid ...
Evidence for left ventricular dysfunction in patients with
Evidence for left ventricular dysfunction in patients with

... Evidence for left ventricular dysfunction in patients with obstructive sleep apnoea syndrome. M. Alchanatis, G. Tourkohoriti, E.N. Kosmas, G. Panoutsopoulos, S. Kakouros, K. Papadima, M. Gaga, J.B. Jordanoglou. #ERS Journals Ltd 2002. ABSTRACT: There is limited information on the development of left ...
Atrial Fibrillation - Florida Veterinary Cardiology
Atrial Fibrillation - Florida Veterinary Cardiology

Comparision between Chest X Ray, Electrocardiogram and
Comparision between Chest X Ray, Electrocardiogram and

... In the standard 12 lead ECG on comparing the Sokolov-Lyon criteria and Romhilt-Estes point score system, it is seen that sensitivity of 64% and specificity of 75% is found in SokolovLyon criteria whereas Romhilt-Estes has sensitivity of 36% and specificity of 89%. Therefore Romhilt-Estes point score ...
Prognostic significance of new onset atrial fibrillation in acute
Prognostic significance of new onset atrial fibrillation in acute

... Results: Patients with new onset of AF were older and more likely to have diabetes, chronic obstructive pulmonary disease, cardiogenic shock and chest pain on admission, and a shorter time from the onset of symptoms to admission. These patients more frequently received glycoprotein IIb/IIIa inhibito ...
Relationship between plasma aldosterone and left ventricular
Relationship between plasma aldosterone and left ventricular

... significant correlation between plasma aldosterone and septal, posterior and relative wall thickness. On the other hand, patients with hypertension and pathologic patterns of left ventricular geometry were characterized by elevation of aldosterone (Muscholl et al, 1998). Additionally, spironolactone ...
the PDF file
the PDF file

... vagus nerve.Next, in part 2 of the experiment, the transducer was calibrated and a copper wire was inserted into the ventricle and then connected to the newly calibrated force transducer. Then the electrical signals were set upaccording to the lab manual (Bautista et al., 2009, pgs. 46-47). Contribu ...
Mark E. Silverman, Daniel Grove and Charles B. Upshaw, Jr Why
Mark E. Silverman, Daniel Grove and Charles B. Upshaw, Jr Why

... that terminated in the Purkinje fibers. Martin Flack and Arthur Keith studied the conduction system of a mole and found a structure in the sinoauricular junction that histologically resembled the AV node. They felt that this was where “the dominating rhythm of the heart normally begins” and named it ...
Prevention of Recurrences of Ventricular Arrhythmias in Patients
Prevention of Recurrences of Ventricular Arrhythmias in Patients

... combination of ischemia and scar is probably responsible for the genesis of lethal arrhythmias. Experimental studies have clearly shown that acute ischemia superimposed on myocardial scar is arrhythmogenic, while the same degree of acute ischemia in the absence of myocardial scar tissue is not (8,9) ...
ecg rhythm interpretation primer - Twin Cities Health Professionals
ecg rhythm interpretation primer - Twin Cities Health Professionals

... fibers located in the muscles of the ventricles. The Purkinje fibers penetrate about 1/4 to 1/3 of the way into the ventricular muscle mass and then become continuous with the cardiac muscle fibers. The electrical impulse spreads rapidly through the ventricular muscle, causing ventricular contractio ...
PTCA and Thrombolytic Therapy in Myocardial Infarction
PTCA and Thrombolytic Therapy in Myocardial Infarction

... out to the body and lungs. • Low ejection fractions if known can help guide therapy ...
relatively inactive adults - British Journal of Sports Medicine
relatively inactive adults - British Journal of Sports Medicine

< 1 ... 323 324 325 326 327 328 329 330 331 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report