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Atypical presentation of an infant with idiopathic pulmonary arterial
Atypical presentation of an infant with idiopathic pulmonary arterial

... effusion itself may be more important than the size of the effusion. Further studies with larger patient cohorts will be needed to clarify the proper evaluation and risk stratification of patients with PAH associated with pericardial effusion. This case report is the first IPAH case in the literatur ...
Assessment of Diastolic Function in Heart Failure and Atrial Fibrillation
Assessment of Diastolic Function in Heart Failure and Atrial Fibrillation

... also a progression of abnormal diastolic patterns that occurs over time with cardiac diseases. In the early stage of dysfunction, impaired relaxation of the LV dominates, which decreases early diastolic filling although filling pressures remain normal in the rest state. This is reflected by a decrea ...
The Rate Dependent Bundle Branch Block
The Rate Dependent Bundle Branch Block

... propanolol, neostigmine and edrophonium which all decrease the heart rate and thus change this aberrant conduction block to normal13. Holter examination, however, is the gold standard. In a chronic hypertensive patient with LBBB, it is always better to do further cardiac evaluation, like stress-imag ...
HYPERTENSION AND ARRHYTHMIA
HYPERTENSION AND ARRHYTHMIA

... (tachycardia and ventricular fibrillation) are still rare (16). Both the incidence and seriousness of these forms correlate with the severity of the LVH, as measured by ECG and ultrasound (17). Asymmetric septal and eccentric hypertrophy seem to be associated more often with ventricular arrhythmia t ...
Successful Emergency Repair of Blunt Right Atrial Rupture after a
Successful Emergency Repair of Blunt Right Atrial Rupture after a

... in four cases, and the RA free wall in three cases. The appendages are most vulnerable because of their thin walls. Atrial rupture has a different mechanism from ventricular rupture. Atrial rupture can be caused by forceful compression of the thorax and heart during late systole at the time when the ...
relation of hemoglobin a to left ventricular diastolic function in
relation of hemoglobin a to left ventricular diastolic function in

... In this study, we found low transmitral E/A ratio as an evidence of reduced diastolic function, left ventricular chamber compliance, and changes in the left atrial pressure. In the presence of mild diastolic dysfunction, early filling is often blunted, leading to an exaggerated atrial contribution t ...
Trial Overview - Clinical Trial Results
Trial Overview - Clinical Trial Results

... Compared to standard IV diuretic therapy for hypervolemic heart failure patients, veno-venous ultrafiltration is: • Superior to aggressive IV diuretic therapy in reducing volume overload • Associated with sustained clinical benefits • Similar to IV diuretics in terms of safety ...
Prognostic importance of serum sodium concentration and its
Prognostic importance of serum sodium concentration and its

... Vol. 73, No. 2, February 1986 ...
Mitral/Tricuspid Regurgitation Due to Myxomatous Heart
Mitral/Tricuspid Regurgitation Due to Myxomatous Heart

... This disorder is a problem that can affect the hearts of adult dogs. In the dog, as in humans, the mitral valve is a trapdoor type of structure inside the heart that separates the two chambers (left atrium and left ventricle) of the left side of the heart; the tricuspid valve likewise separates the ...
5 rIGHt VentrIcular PacInG ImProVes rIGHt Heart FunctIon In
5 rIGHt VentrIcular PacInG ImProVes rIGHt Heart FunctIon In

... Pulmonary arterial hypertension (PH) is characterized by progressive pulmonary vascular remodeling. During the progression of the disease, right ventricular (RV) afterload continues to rise and eventually right heart failure develops in the majority of patients. In PH-patients, signs of mechanical R ...
Syncope and shock
Syncope and shock

... – Caused by sudden failure of the heart as an effective pump. It occurs most commonly as a complication of acute myocardial infarction, but it may also be seen in patients with severe bradyor tachyarrhythmias, valvular heart disease, or in terminal stage of chronic heart failure (ischemic heart dise ...
Amiodarone or an Implantable Cardioverter–Defibrillator for
Amiodarone or an Implantable Cardioverter–Defibrillator for

... randomization. Patients assigned to ICD therapy received their device a median of three days after randomization (interquartile range, two to five). Outpatient implantation of the device was encouraged. ICD testing could not exceed two inductions of ventricular fibrillation. If an initial 20-J shock ...
Chapter 14
Chapter 14

... a. sinoatrial (SA) node which initiates each heartbeat and thus is the heart’s pacemaker b. atrioventricular (AV) node c. atrioventricular (AV) bundle or bundle of His d. right and left bundle branches e. Purkinje fibers 2. The nervous system and various hormones may increase or decrease the pace of ...
60% 1.00% 1.80% - Providence Health
60% 1.00% 1.80% - Providence Health

... inaccessibility or road conditions. This airborne ...
Exercise Rehabilitation Programs for Children With Congenital
Exercise Rehabilitation Programs for Children With Congenital

... increased but not significantly. Indeed, the increase in VOzmax parallelled an increase in heart rate, suggesting that the subject's degree of effort was greater during the follow-up study than during the original study. This investigation may demonstrate an important improvement in exercise efficie ...
Clinical and laboratory features of acute rheumatic fever from 18
Clinical and laboratory features of acute rheumatic fever from 18

... experience also confirmed. No changes in laboratory and microbiological tests have been recently introduced. Echocardiographic investigations have not changed in time though their performance has recently improved. Interestingly, mean recovery presents no significant difference when the same age gro ...
Head-to-head comparison of the diagnostic utility of BNP and NT
Head-to-head comparison of the diagnostic utility of BNP and NT

... USA). Normal ventricular function (i.e., subjects without structural disorder of the heart) was defined by a left ventricular end-diastolic diameter (LVEDD) < 56 mm, without left ventricular hypertrophy or without wall motion abnormities, a right ventricular systolic pressure (RVSP) < 35 mm Hg and a ...
EMS Cardiac Confusion By Lynn Wallis EMT
EMS Cardiac Confusion By Lynn Wallis EMT

... approach along with a general knowledge of arrhythmias will lead to a correct diagnosis. STEP 1: LOCATE THE P WAVE. This is the first and most important step in electrocardiogram diagnosis. *Are the P waves visible? Absence of the P wave can occur secondary to atrial fibrillation. Alternatively, P w ...
Peak cardiac power output and cardiac reserve in sedentary men
Peak cardiac power output and cardiac reserve in sedentary men

... MAP=(SBP-DBP)/3 + DBP,where DBP is the diastolic blood pressure and SBP the systolic blood pressure in millimeters of mercury (mmHg). Cardiac power output was calculated as follows: CPO = MAP x CO x K, where K is the conversion factor (2.22 · 10-3) into watts (12). Cardiac reserve (CR) was calculate ...
High-Intensity Aerobic Interval Exercise in Chronic Heart Failure
High-Intensity Aerobic Interval Exercise in Chronic Heart Failure

... ventricular ejection fraction (LVEF) had an excessive risk for exercise-related morbidity and mortality. In the 3rd edition of Braunwald’s heart disease textbook published in 1988, one could read: “Reduced physical activity is critical in the care of patients with HF throughout their entire course” ...
Collison OCT 2013
Collison OCT 2013

... valve: structure and cavitation. Heart. 2010 Jun;96:994 Collison SP, Mishra YK. What is the role of intraluminal shunts during off-pump surgery? Ann Thorac Surg. 2010; 90:1394 Collison SP and Meherwal ZS. Off pump versus On pump coronary artery bypass: Review of Level 1 evidence. Fortis Med Journal ...
Slide 1
Slide 1

... of each lead on the six limb leads (I, II, II, aVF, aVR, VL) 2. On the MEA diagram, draw a “3segment on each side “ on either the positive or the negative portion of each lead, according to the EKG 3. The MEA must lie within the wedge which has all six arcs spanning it. This gives you a range of 30˚ ...
Transposition of the Great Arteries
Transposition of the Great Arteries

... A. Arrhythmias (Refer to Problem Section on Arrhythmias for further discussion and management) 1. Supraventricular arrhythmias a. Atrial fibrillation b. Atrial flutter c. Other atrial tachycardias (Paroxysmal or persistent) 2. Ventricular tachycardia a. Sustained or not sustained b. Related to progr ...
Central Sleep Apnea in Left Ventricular Dysfunction
Central Sleep Apnea in Left Ventricular Dysfunction

... by demonstrating that patients with asymptomatic LV dysfunction also have a high prevalence of CSA, and that in these patients, severe CSA is associated with impairment in heart rate variability and increased cardiac arrhythmias. In patients with overt heart failure, CSA correlated with pulmonary ca ...
Worksheet
Worksheet

... incomplete block greater than 0. __ is a complete block Q = first negative deflection R = first positive deflection S = any negative deflection after an R wave ...
< 1 ... 321 322 323 324 325 326 327 328 329 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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