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Distribution and Risk Profile of Paroxysmal
Distribution and Risk Profile of Paroxysmal

... Investigators were randomly selected to avoid bias. Among 9816 eligible patients from 831 sites in 26 countries, 2606 (26.5%) had paroxysmal, 2341 (23.8%) had persistent, and 4869 (49.6%) had permanent AF. As AF progressed from paroxysmal to persistent and permanent forms, the prevalence of comorbid ...
Role of Bilateral Sympathectomy in the
Role of Bilateral Sympathectomy in the

... and after sympathectomy. Continuous noninvasive blood pressure (A), heart rate (B), finger pulse volume (C), and skin conductance (D) were recorded at baseline, and during 2 sympathetic stressors (handgrip exercise and mental stress induced by a Trier test) before (solid line) and after (dashed line ...
Cardiovascular disease in patients with chronic kidney disease
Cardiovascular disease in patients with chronic kidney disease

... currently justify guideline recommendations specific to people with CKD for either stable or unstable CAD. In comparison with the general population, patients with CKD are at increased risk of early and late mortality after CABG. Patients on dialysis have a greater perioperative mortality than those ...
12 EKG
12 EKG

... tracing represents electrical activity moving toward the active lead (the green lead in this experiment). Five components of a single beat are traditionally recognized and labeled P, Q, R, S, and T. The P wave represents the start of the electrical journey as the impulse spreads from the sinoatrial ...
Video-Assisted Epicardial Ablation and Left Atrial Appendage
Video-Assisted Epicardial Ablation and Left Atrial Appendage

... nical difficulty, and prolonged cardiopulmonary bypass times [12]. After the implication of pulmonary veins in the pathogenesis of AF [4], catheter-based ablation was developed to electrically isolate the pulmonary veins and further reduce the invasiveness of AF surgery. Ongoing advances in technol ...
Reduction of Device Artifacts using Wideband Late Gadolinium
Reduction of Device Artifacts using Wideband Late Gadolinium

... Purpose. Late gadolinium enhancement (LGE) cardiac MRI is the clinical gold standard for non-invasive characterization of myocardial scar [1]. However, many patients who may benefit from LGE MRI have preexisting implanted cardiac devices such as implantable cardioverter defibrillators (ICD) and pace ...
Proceedings of the 33rd World Small Animal Veterinary
Proceedings of the 33rd World Small Animal Veterinary

... channel antagonists. Atropine response test If these bradyarrhythmias are genuinely related to high vagal tone, they should be easily abolished by the administration of atropine. The recommended protocol is to record an ECG trace, then administer atropine (0.04 mg/kg by subcutaneous injection) and a ...
Slides 3
Slides 3

... Sympathetic from the cardiac plexus supplies all parts of the heart (atria, ventricle and all parts of the conduction system) Parasympathetic from Vagus nerves supply mainly the atria, SA and AV nodes, very little supply to ventricles Sympathetic: increase the permeability of the cardiac cells to Na ...
Cardiac Genetic Investigation of Young Sudden Unexplained Death
Cardiac Genetic Investigation of Young Sudden Unexplained Death

... common after cardiac arrest and LV dysfunction may take two to three weeks to resolve completely. An erroneous diagnosis of cardiomyopathy is not uncommon in this situation. QT prolongation immediately after cardiac arrest and after therapeutic hypothermia or Brugada ECG pattern immediately followin ...
1 Conduction System of the Heart 4
1 Conduction System of the Heart 4

... Sympathetic from the cardiac plexus supplies all parts of the heart (atria, ventricle and all parts of the conduction system) Parasympathetic from Vagus nerves supply mainly the atria, SA and AV nodes, very little supply to ventricles Sympathetic: increase the permeability of the cardiac cells to Na ...
Document
Document

... – 23, after stroke– 10, with arterial hypertension – 130, diabetes mellitus – 21. Some other cardiovascular parameters: blood cholesterol - 4.78±0.08 mmol/l, and left ventricular ejection fraction 54.0±1.06% were also identified. In Table 3 the electrophysiological characteristics of VPC and HRT are ...
Heart murmurs in puppies and kittens - Acapulco-Vet
Heart murmurs in puppies and kittens - Acapulco-Vet

... murmurs for a much longer time, like adult cats. These innocent murmurs are always systolic (decrescendo), located over the left heart base, and should never exceed a grade 3/6. In puppies they should have disappeared by the age of 3.5 months. The continuous murmur of a patent ductus arteriosus (PDA ...
CR_Ectopia Cordis_Hamidur Rahman.indd
CR_Ectopia Cordis_Hamidur Rahman.indd

... heart passes through a defect in the diaphragm to enterthe abdominal cavity3,7.Ventricular septaldefect, atrial septal defect, diverticulum of the ventricle and tetralogy of Fallot are the most common intra-cardiac defects8,9. Omphalocele is the most common abdominal wall defect. The following chara ...
Different Vagal Modulation of the Sinoatrial Node and AV Node in
Different Vagal Modulation of the Sinoatrial Node and AV Node in

... activated than in healthy subjects [161, and parasympathetic tone was reduced. It is conceivable, that this independence is lost in patients with high sympathetic activity. This would be in analogy to exercise in normal subjects, where an increase in sinus rate is associated with a shortening of the ...
Tricuspid Regurgitation After Cardiac Transplantation
Tricuspid Regurgitation After Cardiac Transplantation

... best results are achieved before right ventricular function deteriorates due to severe TR.29 Most patients have shown a reduction in their furosemide dose and lower serum creatinine levels, as well as significantly improved albumin and total bilirubin values, implying relief of hepatic congestion.1, ...
2011 Supraventricular tachycardia causing heart failure
2011 Supraventricular tachycardia causing heart failure

...  Long-standing persistent supraventricular tachycardia (SVT) is a well known cause of nonischemic cardiomyopathy and heart failure, which is known as tachycardia-induced cardiomyopathy (TIC).  SVT-related TIC is a treatable and often reversible cardiomyopathy that is usually a diagnosis of exclusi ...
Document
Document

... atrium and ventricle with the pulmonary circuit and left atrium and ventricle with the systemic circuit. The left ventricle’s greater workload makes it more massive than the right, but the two pump equal amounts of blood. AV valves prevent backflow from the ventricles into the atria, and semilunar v ...
Clinical and Echocardiographic Parameters Associated with Low
Clinical and Echocardiographic Parameters Associated with Low

... Stress test: First, the protocol consisted of twelve-lead ECG and echocardiography at rest after the clinical investigation. Then, physical exertion was made on a treadmill, and soon after, echocardiographic images were taken. All patients underwent a standard Bruce protocol exercise testing. We per ...
Diabetic Cardiomyopathy - Diabetes Care
Diabetic Cardiomyopathy - Diabetes Care

... idiopathic cardiomyopathy is more common in the diabetic patient. While these studies of diastolic dysfunction were performed in diabetic patients with a normal left ventricular mass, left ventricular hypertrophy is more prevalent in type 2 diabetic patients and contributes to ventricular dysfunctio ...
Heart Anatomy (cont)
Heart Anatomy (cont)

... Dual innervation adjusts the autonomic tone to meet the demands of your various systems on the body. The ANS neurotransmitter substances result in a change in the permeability of the conducting system cells, especially the SA nodal cells. ACh opens K+ channels which hyperpolarizes the cell. NE binds ...
RTC PA CATHETER
RTC PA CATHETER

Programmed Ventricular Stimulation - Indications and Limitations: A
Programmed Ventricular Stimulation - Indications and Limitations: A

... the SCD-HeFT study, patients with severe systolic dysfunction are at high risk of sudden cardiac death and are eligible for ICD implantation as prophylactic therapy without the need for PVS.27 Nevertheless, this finding raises many concerns and questions: does this imply a “systematic” implantation ...
figure 4
figure 4

... minimize the “white coat” effect. Allow the animal to become familiar with its surroundings. Establishing contact with the patient is important, especially for the person administering the ECG. Consider owner participation in cases of small dogs or cats, or animals that are especially frightened. Sm ...
Cardiac magnetic resonance imaging-based myocardial strain study
Cardiac magnetic resonance imaging-based myocardial strain study

... Background: Trastuzumab, used to treat breast cancer overexpressing human epidermal growth factor receptor 2, may be cardiotoxic. Cardiac magnetic resonance (CMR) imaging with myocardial strain studies has been used to evaluate subclinical biventricular myocardial changes, however, its clinical util ...
Hemodynamic Measurements of Left Ventricle Function Post
Hemodynamic Measurements of Left Ventricle Function Post

... As load independent parameters are measured, using pre-load reduction by temporary occlusion of inferior vena cava (IVC), a rightward shift of PV loops is observed (Fig. 1). As a good internal control, it is imperative to select for analysis only those samples of IVC occlusion that were performed by ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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