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Diagnostic Value of Cardiovascular Magnetic
Diagnostic Value of Cardiovascular Magnetic

... survivors of myocardial infarction with reduced left ventricular ejection fraction, frequent and repetitive forms of ventricular ectopic activity predicts an increased risk of sudden cardiac death during long-term follow-up (12) In the ATRAMI study, 1071 patients after myocardial infarction were fol ...
Electrical Recording from Hearts with Flexible Nanowire Device Arrays
Electrical Recording from Hearts with Flexible Nanowire Device Arrays

... hearts beat spontaneously at a typical frequency of 1-3 Hz for ca. 20 min.26 Initially, the NWFET response to beating hearts was carried out by simultaneously recording signals from a NWFET and from a conventional glass pipette inserted into the heart.27 Representative data (Figure 1C) show close te ...
INTRODUCTION - California Tumor Tissue Registry
INTRODUCTION - California Tumor Tissue Registry

... not uncommon. Histologically, cardiac leiomyosarcomas resemble their extracardiac counterparts, demonstrating fascicles/bundles of spindle cells, often oriented at sharp angles to one another. Cytologic features such as blunt-ended nuclei, cytoplasmic glycogen, and perinuclear vacuoles are usually s ...
Emergencies related to implantable cardioverter
Emergencies related to implantable cardioverter

... similar to standard pacemaker implantation. They not only provide high-energy shocks for ventricular fibrillation and rapid ventricular tachycardia, but also provide antitachycardia pacing for monomorphic ventricular tachycardia and antibradycardia pacing. Devices incorporating an atrial lead allow ...
Transcripts/4_6 2
Transcripts/4_6 2

... Layers of Pericardial Sac [S3] a. The pericardium is the sac that surrounds the heart b. Sagittal sections through the pericardium and heart c. Pericardium consists of two layers a. Outer thick layer is the fibrous pericardium 1. made up of fibrous connective tissue 2. fused to the diaphragm below a ...
Document
Document

... 7. Ventricular aneurysm: late complication, an outward bulging of the healing infarct during ventricular systole. Aneurysm sac fills with blood rather than being ejected to the aorta and cardiac output is reduced. • Survival – Depends on size, patient’s age, complications, other diseases – Mortality ...
PVC project
PVC project

... The sinus impulse following the PVC may be conducted with a longer PR interval because of retrograde concealed conduction by the PVC into the AV junction slowing subsequent conduction of the sinus impulse. ...
Atrial Baffle Stenosis: A Late Complication after Mustard Repair for d
Atrial Baffle Stenosis: A Late Complication after Mustard Repair for d

... morphologic left ventricle. Communication between the pulmonary and systemic circuits is necessary for infant survival either via an atrial septal defect, patent ductus arteriosus or ventricular septal defect. Ventricular septal defects are the most common associated anomaly, observed in almost half ...
投影片 1
投影片 1

...  Repeated doses of 5-10 mg may be administered every 15-30 minutes to a total dose of 20 mg.  An alternative dosing regimen is to give a 5-mg bolus every 15 minutes to a total dose of 30 mg.  Should be given only to patients with narrowcomplex reentry SVT or arrhythmias known with certainty to be ...
Coherence: A Novel Nonpharmacological Modality for Lowering
Coherence: A Novel Nonpharmacological Modality for Lowering

... patients was then randomly divided into 3 groups. Group 1 (n = 30) was currently taking hypertensive medication as prescribed by their physicians, was taught the self-regulation technique called Quick Coherence (QC),34 and practiced with the emWave PSR device (HeartMath LLC, Boulder Creek, Californi ...
04_Symptoms and syndromes based on the data of auscultation of a
04_Symptoms and syndromes based on the data of auscultation of a

... • 3 - The Third Heart Sound is usually best heard at cardiac apex, in the partial left lateral decubitus position, with the bell of the stethoscope. • 4 - The Fourth Heart Sound is best heard with the bell of the stethoscope, at cardiac apex (left origin) or tricuspid area (right origin). • 5 - In S ...
Ascending Aorta-Right Pulmonary Artery Shunt in
Ascending Aorta-Right Pulmonary Artery Shunt in

... size has a large effect on the total blood flow. Even in the presence of an anastomosis of proper size, there frequently is uneven distribution of flow between the two lungs. The lung on the side of the anastomosis receives about 75% of the blood flowing through the anastomosis, while the opposite l ...
Lab #10: Cardiovascular Physiology
Lab #10: Cardiovascular Physiology

... blood through the body. It does so by undergoing a cycle of contraction and relaxation called the cardiac cycle. During the initial portion of the cardiac cycle, an electrical signal is generated in so-called “pacemaker cells” that is distributed through the heart through an electrical conduction sy ...
Hemodynamics during Humoral Rejection Events with Total Versus
Hemodynamics during Humoral Rejection Events with Total Versus

... Despite ongoing rejection, heart rate, blood pressure, and even cardiac output may frequently remain unchanged up to 24 hours before cardiac arrest.9) Even with myocyte necrosis present systolic function of the transplanted heart does not reliably reflect the results of endomyocardial biopsy.10) In ...
The Heart Failure Clinic: A Consensus Statement of the Heart
The Heart Failure Clinic: A Consensus Statement of the Heart

... 802 Journal of Cardiac Failure Vol. 14 No. 10 December 2008 socioeconomic, and psychologic factors that contribute to morbid events; and development of a mechanism to document and monitor quality. The provision of multidisciplinary individualized care has been cited as a way to minimize intermitten ...
LEFT-TO-RIGHT CARDIAC SHUNT: PERIOPERATIVE
LEFT-TO-RIGHT CARDIAC SHUNT: PERIOPERATIVE

... membranous part of the septum is separated into the pars atrioventricularis and the pars interventricularis by the tricuspid valve. True membranous VSD lesion is completely bordered by fibrous tissue. If the lesion penetrates into any portion of the muscular septum, the defect is named a perimembran ...
YR 2 PATHOPHYSIOLOGY: CARDIOVASCULAR UNIT I
YR 2 PATHOPHYSIOLOGY: CARDIOVASCULAR UNIT I

... discomfort. His rhythm is sinus at 90 bpm; BP 120/85. An ECG shows 3 mm of ST segment depression in leads II, III, AVF, V5 and V6. The best next step is: a. admission with initiation of ASA, ß-blocker, and heparin therapy b. thrombolysis with tPA c. cardiac catheterization and percutaneous translumi ...
The Heart Failure Clinic: A Consensus
The Heart Failure Clinic: A Consensus

... 802 Journal of Cardiac Failure Vol. 14 No. 10 December 2008 socioeconomic, and psychologic factors that contribute to morbid events; and development of a mechanism to document and monitor quality. The provision of multidisciplinary individualized care has been cited as a way to minimize intermitten ...
Hypertension and the JNC 8 Guidelines
Hypertension and the JNC 8 Guidelines

... This left ventricle is very thickened (slightly over 2 cm in thickness), but the rest of the heart is not greatly enlarged. This is typical for hypertensive heart disease. The hypertension creates a greater pressure load on the heart to induce the hypertrophy. ...
Curriculum for Acute Cardiac Care subspecialty training in Europe
Curriculum for Acute Cardiac Care subspecialty training in Europe

the use of thrombolytic agents in acute myocardial infarction
the use of thrombolytic agents in acute myocardial infarction

... Our findings did not resonate with those of GUSTO trials. We found that SK and rt-PA did not differ significantly with respect to CK reduction, lengths of hospitalisation, and ejection fraction. Overall both drugs showed similar efficacy in AMI. Although rt-PA seems to be a more attractive choice as ...
Full text (PDF file)
Full text (PDF file)

... The assessment of ventricular function is an important task in the evaluation of patients with known or suspected heart disease. There are several parameters that can be used to evaluate ventricular function but most of them are relatively dependent on afterload and preload. The maximum rate of rise ...
Clinical factors predicting successful electrophysiologic
Clinical factors predicting successful electrophysiologic

... An antiarrhythmic drug was considered effective if no more than five repetitive ventricular complexes could be initiated after administration. Drug trials were terminated when one effective drug suitable for oral therapy was identified. At electrophysiologicpharmacologic study, patients were conside ...
Clinical Implications of the Echocardiographic Evaluation of Right
Clinical Implications of the Echocardiographic Evaluation of Right

... other methods such as cMRI, to the sometimes difficult diagnosis of ARVD/C, even in the subset of patients with an apparently normal RV by conventional echocardiography.9 It is known that, in pathologic conditions with pulmonary hypertension, the RV myocardial systolic activation delay assessed by T ...
Comparison of Echocardiographic Variables Between Systemic
Comparison of Echocardiographic Variables Between Systemic

... involvement could be silent. Echocardiography can be used as a noninvasive tool for the assessment of the ventricular function. Objectives: We sought to evaluate different echocardiographic parameters via tissue Doppler imaging and speckle-tracking echocardiography (STE) in addition to conventional ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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