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Determining Axis - jan.ucc.nau.edu
Determining Axis - jan.ucc.nau.edu

... the QRS complex for Lead I is positively deflected but the QRS in avF is negatively deflected, then the electrical axis is said to be left axis deviated (up,down) ...
Plastination of the heart: preparation for the study of the cardiac valves
Plastination of the heart: preparation for the study of the cardiac valves

... Visualize the coronary arteries and/or myocardium. To study the cardiac valves, the dissection is performed in a way that permits Visualization of the valves and their relationship to each other and adjacent structures. In either case, it is difficult to make permanent specimens, free of fixatives f ...
Socioeconomic Disparities in the Use of Cardioprotective
Socioeconomic Disparities in the Use of Cardioprotective

... of the patient’s zip code of residence. This approach to categorize levels of socioeconomic status has been used in previous reports of various disease conditions (25–27). The primary study outcome was treatment with two secondary preventive medications: an antiplatelet agent (aspirin or clopidogrel ...
Patient Selection in Heart Failure With Preserved Ejection Fraction
Patient Selection in Heart Failure With Preserved Ejection Fraction

... Recent clinical trials in patients with heart failure with preserved ejection fraction (HFpEF) have provided important insights into participant selection strategies. Historically, HFpEF trials have included patients with relatively preserved left ventricular ejection fraction ranging from 40% to 55 ...
Rhythm or rate control in persistent atrial fibrillation
Rhythm or rate control in persistent atrial fibrillation

... control strategies which obviate some of the adverse effects related to anti-arrhythmic medications. Haïssaguerre and colleagues demonstrated that AF was initiated by atrial extrasystoles originating, in the majority of cases (94% of triggers), in the pulmonary veins (PVs) [6] . The importance of th ...
Multiple premature ventricular contractions favouring heart failure in
Multiple premature ventricular contractions favouring heart failure in

... WIDER PVC QRS duration (epicardial ?) NON OUTFLOW TRACT site of origin PVC coupling interval ...
a sudden death following cardiomyopathy in a child
a sudden death following cardiomyopathy in a child

... syncopal attacks over the past one year. Perusal of the initial clinical records revealed cardio-thoracic ratio (CTR) of 55%, normal cardiac valves, biventricular hypertrophy, trivial mitral and tricuspid regurgitation with no right or left ventricular outflow obstruction. At this point the patient ...
A study of left ventricular dysfunction and hypertrophy by various
A study of left ventricular dysfunction and hypertrophy by various

... dysfunction and failure (or) secondary to segmental myocardial disease involving the papillary muscle or its subjacent left ventricular wall. The results from this study indicated that there is an increase in left ventricular mass in diabetics as compared to people who are non diabetics. The MILISha ...
The Management of Patients with Premature Ventricular Contractions
The Management of Patients with Premature Ventricular Contractions

... In patients with a previous myocardial infarction many studies have reported an increased mortality and/or an increased frequency of sudden death in patients with PVCs or advanced grades of PVCs. 14 - 1 8 Although there is some variabliity in the reported studies, the increased mortality appears to ...
Acute Heart Failure Syndromes in Patients With Coronary Artery
Acute Heart Failure Syndromes in Patients With Coronary Artery

... AHFS represent a heterogeneous group of patients in terms of their clinical presentation, pathophysiology, prognosis, and therapeutic options (1). The majority of patients presenting with AHFS have coronary artery disease (CAD). These patients may present in 1 of 2 ways: acute coronary syndromes (AC ...
left-sided_congestive_heart_failure
left-sided_congestive_heart_failure

...  Severe sodium restriction is indicated in pets with advanced disease ...
Left-Sided Congestive Heart Failure
Left-Sided Congestive Heart Failure

...  Severe sodium restriction is indicated in pets with advanced disease ...
Tilburg University Type D personality is a predictor
Tilburg University Type D personality is a predictor

... (Schiffer et al. 2005). Both studies showed that Type D was associated with poorer quality of life and health status, adjusting for demographic and clinical characteristics, including left ventricular dysfunction and New York Heart Association (NYHA) functional class (Schiffer et al. 2008a, b, 2005) ...
Ventricular Septal Defect (VSD)
Ventricular Septal Defect (VSD)

... conjunction with other cardiac abnormalities. While little is known about the cause of VSDs, they may be heritable in Limousine and Hereford cattle. ...
Transposition of the Great Arteries (TGA)
Transposition of the Great Arteries (TGA)

... The hospital mortality for ASO performed at RCH, Melbourne from 1985-1997 was 0.9% for TGA/IVS and 4.1% for TGA/VSD. Following discharge from PICU, complications are rare. Late death after newborn TGA has been rare with reports documenting survival at 10 and 15 years as 92-93% and 86% respectively. ...
The incidence of atrial arrhythmias during inferior wall myocardial
The incidence of atrial arrhythmias during inferior wall myocardial

... Basedon the radionuclear data, patients weregroupedas follows: group A-36 patients (58%) with depressedRVEF (mean -+ SD, 31 -+ 6%) and group B-26 patients (42%) with normal RVEF (mean + SD, 47 + 5%). Holter monitoring procedure. Sixty-two patients had 24-hour HM during the first 24hours following ad ...
The SynCardia CardioWeste Total Artificial Heart
The SynCardia CardioWeste Total Artificial Heart

... have lead to a “shift to the right” of the mortality curve for CHF, with patients living longer with improved quality of life. Unfortunately once patients reach the steep or rapidly declining phase of the mortality curve, i.e. being classified as AHA/ACC Class D and NYHA Class IV CHF, their decline ...
Fontan Procedure Part 2 By Dr. Madhusudan Raikar
Fontan Procedure Part 2 By Dr. Madhusudan Raikar

...  Cardiac MRI – best modality  Cardiac catheterization ...
The Clinical Value of Total Isovolumic Time
The Clinical Value of Total Isovolumic Time

... for managing such patients. Heart failure and dyssynchrony A significant percentage of HF patients remain symptomatic, in NYHA class III-IV, despite full medical therapy. Studies have shown that these patients might benefit from cardiac resynchronization therapy (CRT) (23-26), particularly those pre ...
bYTEBoss Ventricular arrhythmias EP overview Medtronic
bYTEBoss Ventricular arrhythmias EP overview Medtronic

... resulting ECG should be identical to the ECG taken during tachycardia • Delivering RF energy to this site usually eliminates ventricular tachycardia ...
Antioxidant Therapy Reduces Oxidative and Inflammatory Tissue
Antioxidant Therapy Reduces Oxidative and Inflammatory Tissue

... myocardium as part of the ischaemia reperfusion event. Oxidative stress also could generate structural and electrical modifications that would be a substrate for the cardiac dysfunction. In this regard, patients developing reperfusion arrhythmias have increased systemic and myocardial oxidative stre ...
Resting heart rate rapid reduction by moderate exercise
Resting heart rate rapid reduction by moderate exercise

... Physical inactivity became a global pandemic responsible for over 5 million deaths annually through its effects on multiple non-communicable diseases require urgent multidisciplinary health response (1). Not unexpectedly, exercise capacity is a more powerful predictor of cardiovascular (CV) disease ...
Exercise training increases arterial compliance in patients with
Exercise training increases arterial compliance in patients with

... distance walked remained unchanged. To our knowledge, the present study is the first report in which the effects of this type of training regime (a combination of light weights and aerobic exercise using both cycling and walking) has been examined in heart failure patients. It is well documented tha ...
Effect of Elective Percutaneous Coronary Intervention on Left
Effect of Elective Percutaneous Coronary Intervention on Left

... Abstract- Coronary artery disease is one of the most common causes of mortality and morbidity across the world. Its treatment includes medical treatment, coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI). The purpose of this study was to investigate the effect of PCI o ...
crustacean cardioexcitatory peptides may inhibit the heart in vivo
crustacean cardioexcitatory peptides may inhibit the heart in vivo

... (McGaw et al. 1994). Few other in vivo studies have been reported, but both proctolin and F1 failed to increase the heart rate of lobsters (Homarus americanus) after infusion into the pericardial sinus (McMahon, 1992), and proctolin caused transient bradycardia followed by moderate tachycardia in Ca ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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