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Clinical Application of Echocardiography
Clinical Application of Echocardiography

... regurgitation with ventricular dilation without clinical symptoms. 7. Assessment of the effects of medical therapy on the severity of regurgitation and ventricular compensation and function when it might change medical management. ...
Left Ventricular Pseudoaneurysm Caused by Infective Endocarditis
Left Ventricular Pseudoaneurysm Caused by Infective Endocarditis

... Staphylococcus aureus. Treatment with oxacillin 2 g every 4 hours gradually reduced the fever. Echocardiography then showed an aneurysm-like structure communicating with the left ventricle. However, the patient refused further examinations and insisted on discharge. After 4 days, he was readmitted t ...
Influence of physical exercise and relationship with biochemical
Influence of physical exercise and relationship with biochemical

... binding capacity of albumin for transition metals, like cobalt. It has been recently hypothesized that IMA generation in vivo might be interpreted as an efficient endogenous signal or mechanism of response to ischemia, preventing myocardial damage or limiting the burden of myocyte necrosis [4]. On t ...
Lab 3: Mammalian circulation (fetal pig dissection, cow heart, ECG
Lab 3: Mammalian circulation (fetal pig dissection, cow heart, ECG

... The average resting heart rate for adult humans is approximately 70 bpm. Slower heart rates are typically found in individuals who regularly exercise. Athletes are able to pump enough blood to meet the demands of the body with resting heart rates as low as 50 bpm. Athletes tend to develop larger hea ...
Patient Info SVT
Patient Info SVT

... Long-term treatment of SVT can include management with medications or a more invasive approach with catheter ablation. Medical management commonly includes treatment with one or more atrioventricular (AV) nodal blocking agents such as beta blockers (metoprolol, propranolol, atenolol) or calcium cha ...
- STRESS ECHO 2020
- STRESS ECHO 2020

... is CNR-IFC Pisa) 3 - Inclusivity (it was all CCU’s, it is all SE labs of the nation) 4 – Emphasis on clinical relevant outcomes changing patient care (it was thrombolytic therapy in acute myocardial infarction, it is cardiac imaging within and beyond CAD) Braunwald E, Am Heart J, 2004: The GISSI twe ...
Ventricular Tachycardia in Structurally Normal Hearts: Recognition
Ventricular Tachycardia in Structurally Normal Hearts: Recognition

... Idiopathic ventricular tachycardia is a defined set of tachycardias when structural or pathological cause has been ruled out for the same. This paper tries to define and classify these arrhythmias to organize a logical therapeutic approach to deal with them. 60-80% of the idiopathic tachycardias ori ...
miopericarditis – diagnostic dilemmas in relation to acute myocardial
miopericarditis – diagnostic dilemmas in relation to acute myocardial

... culture were bacteriologically negative. The results of immunological analysis indicated the increased values ​​of circulating immune complexes - 235 (reference values ​​for adults up to 160 Nm), discretely elevated serum C3 complement components - 1.73 (reference range 0.8-1.7g / l), while the valu ...
The clinical and etiological profile of atrial fibrillation after
The clinical and etiological profile of atrial fibrillation after

... Background: Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. In western countries, rheumatic heart disease (RHD) is a rare cause of atrial fibrillation but in developing countries like India it is one of the commonest cause of atrial fibrillation. We studied eti ...
Clinical significance of matrix metalloproteinases activity in acute
Clinical significance of matrix metalloproteinases activity in acute

... infarction (MI) patients. Their activity is tightly controlled in normal myocardium by a family of closely related tissue inhibitors known as TIMP. An imbalance in their activity might contribute to post-MI remodeling. Plasma levels of MMP-1, TIMP-1 and MMP-1/TIMP-1 complex were measured, using rele ...
18 The Cardiovascular System: The
18 The Cardiovascular System: The

... (c) Second-degree heart block. (d) Ventricular fibrillation. These chaotic, grossly irregular ECG Some P waves are not conducted deflections are seen in acute through the AV node; hence more heart attack and electrical shock. P than QRS waves are seen. In this tracing, the ratio of P waves to QRS wa ...
ACLS Pharmacology Overview
ACLS Pharmacology Overview

... ACLS PHARMACOLOGY OVERVIEW According to the American Heart Association, there are very few drugs that are well supported when dealing with cardiac arrest and pre-arrest arrhythmias. Because of this, priority is placed on high quality CPR, Defibrillation, airway management and lastly the use of IV dr ...
August - Congenital Cardiology Today
August - Congenital Cardiology Today

... More than 4 million patients are admitted to an and specific responsibility, as well as Intensive Care Unit (ICU) each year in the United accountability for patient care for patients who States. Research has demonstrated that have undergone congenital cardiac surgery. cohorting patients with respect ...
Full sternotomy with limited skin incision for surgical treatment of
Full sternotomy with limited skin incision for surgical treatment of

... Figure 5. Complications included wound dehiscence requiring sutures in one patient. ...
Myocardial Microvascular Inflammatory Endothelial Activation in
Myocardial Microvascular Inflammatory Endothelial Activation in

... to diastolic left ventricular (LV) dysfunction and heart failure with preseved ejection fraction (HFpEF) through coronary microvascular endothelial activation, which alters paracrine signalling to cardiomyocytes and predisposes them to hypertrophy and high diastolic stiffness. BACKGROUND Metabolic r ...
A randomized controlled trial of oxygen therapy in acute myocardial
A randomized controlled trial of oxygen therapy in acute myocardial

... analysis from a contiguous short axis FIESTA stack (8 mm slice thickness) covering the LV and right ventricle from the apex to a level well above the atrio-ventricular groove using the summation of disc method 34 by two blinded cardiologists. For area-atrisk determination, LV short-axis slices cover ...
Diagnosis, management, and outcomes of patients with
Diagnosis, management, and outcomes of patients with

... three-phase diagnostic strategy: Phase I, initial evaluation; Phase II, electrophysiological study (EPS); and Phase III, insertion of an implantable loop recorder (ILR). Overall, 323 patients (left ventricular ejection fraction 56 + 12%) were studied. The aetiological diagnosis was established in 26 ...
Swann Ganz Catheterisation and Cardiac Outputs
Swann Ganz Catheterisation and Cardiac Outputs

... in practise the timing of the injections is difficult ...
Anesthesia Assistants Review Course
Anesthesia Assistants Review Course

... We are writing to give you some assistance as you prepare for the upcoming AAOMS Anesthesia Assistant’s Review Course (AARC) which you will be attending on March 4-5, 2017. Over the years it has been our experience that the EKG/Dysrhythmia material is the most difficult for the attendees. Although s ...
Activity 5.3.2: Heart Matter
Activity 5.3.2: Heart Matter

... Listen carefully. Can you hear or feel your heart beating? What do you know about your heart other than it is beating? How does blood enter and exit the heart? What do the valves do? What happens when something doesn’t work correctly? What kinds of heart dysfunctions exist, and which ones can be cor ...
Electrical Conduction Disturbance Effects on Dynamic
Electrical Conduction Disturbance Effects on Dynamic

... consisted of 60 patients (44 males, mean age 60 ⫾ 10 years). Eighteen had idiopathic dilated cardiomyopathy, and 42 patients had a history of myocardial infarction (20 in the anterior wall, 17 in the inferoposterior wall, and 5 in both the anterior and inferoposterior walls). Echocardiography docume ...
Pacemaker Emergencies - Calgary Emergency Medicine
Pacemaker Emergencies - Calgary Emergency Medicine

... Pocket Complications Hematomas  Occur after implantation-venous or arterial bleeder (check for anticoagulation)  If the size of your palm - needs surgery ...
Redalyc.Transapical Closure of Left Ventricular to Right Atrial Shunt
Redalyc.Transapical Closure of Left Ventricular to Right Atrial Shunt

... was guided by transepicardial echocardiography to define the puncture site and with 3D TEE for guidance during the procedure. Right femoral vein puncture to access the Gerbode defect was also performed, forming a loop with the transapical access. A pigtail catheter was advanced through the left femo ...
Pulmonary Arterial Hypertension - Coram CVS Specialty Infusion
Pulmonary Arterial Hypertension - Coram CVS Specialty Infusion

... has been shown to be a strong predictor of survival; again, this emphasizes the importance of early diagnosis and intervention. Unfortunately, most patients are not diagnosed until they reach Class III or IV. PAH is rarely identified in a routine medical examination and, even in its later stages, it ...
Search for HRV‐parameters that detect a sympathetic - UvA-DARE
Search for HRV‐parameters that detect a sympathetic - UvA-DARE

... Table 1 gives an overview of the chosen 11 HRV parameters in patients and control subjects  in the supine posture. It is remarkable that the mean supine heart rates, pIBI‐50 and rMSSD  in the two groups are equal despite the ß‐blockade in the patients. Total variability as  expressed by SD‐IBI is lo ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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