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Typical atrioventricular nodal reentrant and orthodromic
Typical atrioventricular nodal reentrant and orthodromic

... catheter and followed by a 10 cc (cubic centimeter or milliliter) saline flush [1,19,24]. A lower dose (3 mg) is recommended in persons who have a cardiac transplant [20]. Adverse effects occur in about 40% of cases, such as dyspnea, chest pain and some rhythm disturbances (asystole, bradycardia, ex ...
Relationship between Myocardial Performance Index and Severity
Relationship between Myocardial Performance Index and Severity

... Coronary artery disease (CAD) is a leading cause of morbidity and mortality worldwide, and its incidence has been gradually increasing. CAD is a progressive inflammatory disease in which atherosclerosis plays a major role in its etiology [1]. The SYNTAX score (SS) is a lesion-based angiographic scor ...
Cardiac Biomechanics
Cardiac Biomechanics

... through the cardiac cycle. The ventricular walls in the normal heart are thickest at the equator and base of the left ventricle and thinnest at the left ventricular apex and right ventricular free wall. There are also variations in the principal dimensions of the left ventricle with species, age, ph ...
The Alternation Atrial Flutter and Atrial Fibrillation* `
The Alternation Atrial Flutter and Atrial Fibrillation* `

... with a history of embolization and only three of 17 in the postoperative ...
Defibrillation
Defibrillation

... Defibrillation is performed to correct lifethreatening fibrillations of the heart, which could result in cardiac arrest. It should be performed immediately after identifying that the patient is experiencing a cardiac emergency, has no pulse, and is unresponsive. ...
The Fontan Circulation: The Known, the Unknown and
The Fontan Circulation: The Known, the Unknown and

... right ventricular contraction duration, which is not possible in Fontan patients [15]. No significant improvement in 6 min walking distance was seen in a small group of 10 failing Fontan patients treated with bosentan for 12 weeks. In another small study of eight patients, bosentan showed improvemen ...
TRACS Randomized Controlled Trial Transfusion
TRACS Randomized Controlled Trial Transfusion

... bloodtransfusion,varyingfrom 40% to 90% in most reports.1-3 The rationale for perioperative red blood cell (RBC) transfusion is based on the observation that anemia is an independent risk factor for morbidity and mortality after cardiac operations.4,5 However, transfusions have been associated with ...
Acute rosiglitazone treatment is cardioprotective against - AJP
Acute rosiglitazone treatment is cardioprotective against - AJP

... receptor (PPAR)-␥ agonist indicated for the treatment of type 2 diabetes, has been shown to possess cardioprotective properties in vivo during I/R (1, 23, 36) and in patients after percutaneous coronary intervention (40). However, the use of this drug remains controversial as recent meta-analyses an ...
Defibrillation
Defibrillation

Cardioversion of "Common" Atrial
Cardioversion of "Common" Atrial

... pital admission, the patient developed atrial flutter with a ventric¬ ular rate of 90 bpm. Attempt to restore sinus rhythm with oral quinidine sulfate failed. Because of rapid ventricular rate contrib¬ uting to worsening angina, electrical cardioversion was performed following transesophageal echoca ...
Influence of Left Ventricular Diastolic Function on Exercise
Influence of Left Ventricular Diastolic Function on Exercise

... culopathy, but also by a significant increase in left ventricular (LV) filling pressure. This study evaluated the influence of LV diastolic function on EIPH in patients with systemic sclerosis (SSc). Methods: The study included 222 SSc patients (age 58.9 ± 13.1 years, 85% female) and 30 controls wit ...
Advances in Arrhythmia and Electrophysiology
Advances in Arrhythmia and Electrophysiology

... fashion previously described for patients with left bundle branch block or chronic right ventricular pacing.25–29 Right ventricular pacing is notably associated with dyssynchronous ventricular contraction,39 changes in cardiac sympathetic activity, histopathology as well as ion channel expression an ...
Sympathetic Activity in Patients With Panic Disorder at Rest, Under
Sympathetic Activity in Patients With Panic Disorder at Rest, Under

... We used an isotope dilution technique, concurrently administering radiolabeled epinephrine and norepinephrine21 to measure the rates of whole-body and cardiac spillover of both catecholamines. Blood samples were obtained from coronary sinus and brachial or radial arterial catheters that were percuta ...
PDF - Columbia University Department of Surgery
PDF - Columbia University Department of Surgery

... us to combine TAVR’s new delivery with conventional aortic valve replacement surgery. n For more information, please visit columbiasurgery.org. To schedule an appointment for TAVR EVALUATION, call 212.305.4134. ...
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... to further study echocardiographic markers of right ventricular contractile reserve in search of a noninvasive correlative parameter to the haemodynamic markers of contractile reserve and RV-PA coupling. The study by SHARMA et al. [12] may help answer this final question. The authors compared right ...
Exercise Prescription for Cardiovascular Diseases
Exercise Prescription for Cardiovascular Diseases

... with slight reduction in intensity (40-70% of VO2max or HRR, i.e. 5580% of the maximal heart rate.) The lower range of intensity is sufficient for the elderly. 3 or 4 times weekly for at least 30 minutes at a time Various endurance exercise modes are suitable. Resistance training (preferably circuit ...
2 - 张丽
2 - 张丽

... were divided into three age groups: a youth group (19–45 y old), a middle-age group (46–64 y old ) and an old-age group (≥65 y old). Basal and apical short-axis images of left ventricular were acquired to analyse LV rotation (LVrot) and LVrot velocity. LVtw and LVtw velocity was defined as apical LV ...
Secondary Prevention of Atherosclerotic Cardiovascular Disease
Secondary Prevention of Atherosclerotic Cardiovascular Disease

... Specific statins and doses are noted in bold that were evaluated in RCTs included in CQ1, CQ2 and the CTT 2010 meta-analysis included in CQ3. All of these RCTs demonstrated a reduction in major cardiovascular events. Statins and doses that are approved by the U.S. FDA but were not tested in the RCTs ...
Evaluation of right and left ventricular function using speckle tracking
Evaluation of right and left ventricular function using speckle tracking

... longitudinal strain based on speckle tracking can detect subtle right (RV) or left ventricular (LV) dysfunction as an early sign of ARVC. Methods and results: Seventeen male patients, fulfilling Task force criteria for ARVC, 49 (32–70) years old, nineteen male first degree relatives 29 (19–73) y.o. ...
Relation between acute hyperglycemia and contrast
Relation between acute hyperglycemia and contrast

... renal failure requiring a renal replacement therapy (4.8% vs 8.2%, P = .007) and a lower incidence of acute kidney injury (9% vs 12.3%, P = .04).(26) These findings underline the importance of control of acute hyperglycemia as a possible prophylactic strategy for prevention of CIN in STEMI patients ...
The utility of cardiac MRI in diagnosis of infective endocarditis
The utility of cardiac MRI in diagnosis of infective endocarditis

... life-threatening infectious syndrome (11, 12). Infection-related endothelial damage leads to cell death and surface deterioration (1). Further damage and infarction may occur if endocarditis progresses into myocarditis or if vegetation causes coronary artery embolization. This damage and infarction ...
Polymorphous Ventricular Tachycardia
Polymorphous Ventricular Tachycardia

... class Ia drugs at the onset of PVT and those with primary or secondary ventricular fibrillation were not included in the study. However, one patient (3) was included who had initially received three doses of quinidine but continued having recurrent episodes of PVT more than 72 hours after the quinid ...
Targeting Reactive Oxygen Species Production To Prevent Left
Targeting Reactive Oxygen Species Production To Prevent Left

... not well understood and currently, no medical therapy exists to treat this condition. Cardiac VO is marked by eccentric remodeling and contractile dysfunction ultimately resulting in cardiac failure. Oxidative stress is implicated in the pathophysiology of heart failure and recent evidence suggests ...
Pre-Operative Risk Factors of Bleeding and Stroke During
Pre-Operative Risk Factors of Bleeding and Stroke During

... likelihood of the development of post-operative hemorrhagic or thrombotic complications. Knowing which patients are at greater risk might assist in tailoring anticoagulation therapy for certain patients. ...
Common Causes of Troponin Elevations in the Absence of Acute
Common Causes of Troponin Elevations in the Absence of Acute

... treatment of HF in 75% of their 12 patients whose serial measurements of TnT were available. In one third of this group, TnT levels dropped below detectable limit after treatment. Unfortunately, the value of the pattern of TnT response to medical therapy in predicting the long-term outcome was not r ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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