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Paroxysmal stress-induced atrial tachycardia as an unusual cause
Paroxysmal stress-induced atrial tachycardia as an unusual cause

... tachycardia with a 1.4 seconds pause of sinus node activity during which 2 ventricular and 2 atrial escape beats emerged and symptoms were reproduced. During electrophysiologic study both burst pacing and isoproterenol but not programmed stimulation easily induced the tachycardia suggesting a trigge ...
12 Lead EKG 101
12 Lead EKG 101

... single most important element to identify on the ECG when looking for evidence of AMI. ...
Articles in PresS. Am J Physiol Heart Circ Physiol (September 25
Articles in PresS. Am J Physiol Heart Circ Physiol (September 25

... constant of isovolumic relaxation (τ), and elevated EDP with normal ejection fraction. Isovolumic ...
TotaI Excitation of the IsoIated Human Heart
TotaI Excitation of the IsoIated Human Heart

... perfusion of the heart influenced the excitation of the ventricle. Five mongrel dogs, weighing 18 to 24 kg, were anesthetized with Na-pentobarbital (30 mg/kg). A midstemal thoracotomy was performed, and the heart was exposed. Multielectrode needIes were inserted into the ventricular wall, in one or ...
BME 311: BIOMEDICAL INSTRUMENTATION I Lecturer: Ali Işın
BME 311: BIOMEDICAL INSTRUMENTATION I Lecturer: Ali Işın

... • constantly monitors patients heart rate and rhythm. When it detects a very fast, abnormal heart rhythm, it delivers energy to the heart muscle. This causes the heart to beat in a normal rhythm again. • Similar to pacemakers, these devices typically include electrode wire(s) that pass through a ve ...
Effects of inhaled salbutamol in primary pulmonary hypertension
Effects of inhaled salbutamol in primary pulmonary hypertension

... any bias can not be fully excluded. The study was not designed to address long-term effects of inhaled b2-agonists in PPH. It is unclear whether the demonstrated acute effects have any substantial meaning for long-term treatment. In conclusion, this pilot trial on the effects of inhaled salbutamol i ...
Permanent transvenous pacemaker implantation in a patient with
Permanent transvenous pacemaker implantation in a patient with

... patient with non-obstructive cor triatriatum dextrum. Cor triatriatum dextrum is an extremely rare congenital heart abnormality in which the right atrium is separated into two chambers by the persistence of the right sinus venosus valve[3]. The superior chamber receives the venous blood from both v ...
grupo latido
grupo latido

... CONCEPT: It is a ventricular rhythm with a sequence of ≥ 3 consecutives monomorphic ectopic ventricular beats, lasting less than 30 s gradual onset with a long coupling interval and the end by a gradual decrease of the ventricular rate or increase of the sinus rate and, last but not least, by a good ...
Print - Circulation
Print - Circulation

... surgery, resection or imbrication of the sac should be accomplished to prevent further enlargement, associated cardiac arrhythmias, ...
Rate versus rhythm control in atrial fibrillation and
Rate versus rhythm control in atrial fibrillation and

... One hundred and fifty-seven studies were found in the database search and 146 studies were excluded: 11 were not RCTs; 36 were not AF studies; 73 citations reported trials that did not compare pharmacological rate versus rhythm control in AF; and 26 records were substudies of eligible trials. Eleven ...
Mannequin - CHFpatients.com
Mannequin - CHFpatients.com

... The TR3ISVR™ procedure helps to ensure predictable and reproducible outcomes. To restore the ventricle to its more anatomically correct size, shape and orientation, the Mannequin™, (Chase Medical, Richardson, TX) an endoventricular shaping device, is inserted into the ventricle allowing for optimiza ...
Echocardiographic studies of the motion of the mitral valve in
Echocardiographic studies of the motion of the mitral valve in

... rysm,1° bicuspid aortic valve," and supravalvular aortic stenosis12have been described in recent publications. In this report, echocardiographic manifestations are described in patients with ruptured aortic valvular leaflets in the absence of valvular vegetations (confirmed either at surgery or post ...
Myocardial cytokine gene expression is higher in aortic
Myocardial cytokine gene expression is higher in aortic

... their respective receptors.14 In addition unloading of the terminally failing heart by venting13 or by prolonged mechanical circulatory support15 results in a downregulation of myocardial TNFa gene expression.16 Taken together these data suggest that haemodynamic factors such as wall stress have a m ...
Improved reperfusion and clinical outcome with
Improved reperfusion and clinical outcome with

... patients in these studies received aspirin. Furthermore, intravenous heparin did not improve outcome over subcutaneous heparin when added to streptokinase in the first Global Utilization of Streptokinase and t-PA for Occluded coronary arteries-study I GUSTO-I[9]. Worldwide, streptokinase is the most ...
DEVELOPING A MODEL THREE-DIMENSIONAL ANIMATION OF
DEVELOPING A MODEL THREE-DIMENSIONAL ANIMATION OF

... Myocardin, a novel gene recently discovered by Dr. Olson, has a similar expression pattern to Nkx2.5. Its expression is initiated in the cardiac crescent at the time of cardiogenic specification, and continued to be found in the atrial and ventricular chambers of the heart during later development ( ...
Review Article - Departamentos e GEs
Review Article - Departamentos e GEs

... imaging, computed tomography and PET-CT, with three-year follow-up21. The results may provide insights that will assist us in assessing cardiovascular risk. The role of PET-CT in cardiac sarcoidosis Sarcoidosis is a systemic disease of an unknown cause characterized by the presence of noncaseating g ...


... coordinated fashion, supporting a heart rhythm. This rhythm is responsive to all sorts of stimulation both positive and negative, such as stress, exercise, fever, hormones, drugs and nervous system signals. Nervous system input and the level of hormones in the blood strongly influence the rate of th ...
Arrhythmogenic right ventricular cardiomyopathy in a dog
Arrhythmogenic right ventricular cardiomyopathy in a dog

... instances26. Although it has been termed right ventricular dysplasia in some of the literature referring to humans 3,10,20,21 , abnormal embryogenesis is not believed by all investigators to be involved6,9, and the term cardiomyopathy may be more appropriate. Ventricular tachycardia (often of left o ...
Heart Failure: Causes and Nursing Management
Heart Failure: Causes and Nursing Management

... (National heart lung and blood institute 2011, 6).In hyperthyroidism, increase in tissue metabolism, low systemic vascular resistance and increase in total blood volume have a corresponding in cardiac output. Increase cardiac output also increases resting heart rate, thus increasing systolic blood p ...
Data from a study of 54 healthy subjects administered a... dasatinib 30 minutes following consumption of a high-fat meal indicated...
Data from a study of 54 healthy subjects administered a... dasatinib 30 minutes following consumption of a high-fat meal indicated...

... primary efficacy endpoint in these trials was major cytogenetic response (MCyR). An open-label, randomised, comparative multicentre study was conducted in patients who failed initial treatment with 400 or 600 mg imatinib. They were randomised (2:1) to either dasatinib (70 mg twice daily) or imatinib ...
Use of Injectable Potassium Chloride for
Use of Injectable Potassium Chloride for

... and esthetically acceptable for personnel carrying out the procedure. It is also stated that a euthanasia method should “…produce rapid unconsciousness and thus assurance of insensitivity to pain; this must be followed by cardiac and respiratory arrest.” Death can be due to either direct or indirect ...
Document
Document

... The study population included 111 patients from three tertiary-care centers in Switzerland with a definite (n = 80), borderline (n = 19), and possible (n = 12, all first degree family members of patients with confirmed ARVC/D) diagnosis of ARVC/D according to the 2010 TFC, who had an ECG recorded be ...
Poster Arrhythmia Recognition Part 1
Poster Arrhythmia Recognition Part 1

... Arrhythmia Recognition (poster 1 of 2) This is part one of two posters to assist healthcare professionals in recognizing basic arrhythmias. According to the Practice Standards for Electrocardiographic Monitoring in Hospital Settings (Circulation. 2004;110:2721-2746) in general, the mechanisms of arr ...
Document
Document

... Consulting Fees & Speakers Honoraria received by Hoffman La Roche 9803mo01, 2 ...
Epidemiology of Stroke and Death in Atrial Fibrillation
Epidemiology of Stroke and Death in Atrial Fibrillation

... quality of data retrieval; however, in other settings, it may be necessary to validate data entries against medical records6. In this present study, data in the used registers were very reliable which a previous study has concluded after validating these data12,13. However, often investigators do no ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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