Baroreflex sensitivity changes with calcium antagonist
... elderly subjects, predominantly with either angiotensin-converting enzyme inhibitors9–12 or with calcium channel blocking drugs.12–17 The basis for the observed increases in BRS with treatment, although not seen in every study,17 is thought to be an increase in large artery compliance permitting res ...
... elderly subjects, predominantly with either angiotensin-converting enzyme inhibitors9–12 or with calcium channel blocking drugs.12–17 The basis for the observed increases in BRS with treatment, although not seen in every study,17 is thought to be an increase in large artery compliance permitting res ...
Atrial Septal Defect Presenting in a 70-Year
... 6% per year after age 40 years. Progressive symptoms of dyspnea on exertion and palpitations frequently occur in adulthood and are caused by increasing right-sided chamber enlargement, pulmonary hypertension, RV failure, tricuspid regurgitation, and atrial arrhythmias.1 Hereby, we report an unusual ...
... 6% per year after age 40 years. Progressive symptoms of dyspnea on exertion and palpitations frequently occur in adulthood and are caused by increasing right-sided chamber enlargement, pulmonary hypertension, RV failure, tricuspid regurgitation, and atrial arrhythmias.1 Hereby, we report an unusual ...
+ = BeSt OutcOmeS Pediatric Heart Surgery
... a less invasive hybrid technique for a difficult-to-treat defect in newborns known only one in the Tri-State area. as hypoplastic left heart syndrome (HLHS). To survive, babies born with this anomaly must undergo surgery in the first week of life. Until recently, the only treatment available was the ...
... a less invasive hybrid technique for a difficult-to-treat defect in newborns known only one in the Tri-State area. as hypoplastic left heart syndrome (HLHS). To survive, babies born with this anomaly must undergo surgery in the first week of life. Until recently, the only treatment available was the ...
Pediatric Heart Surgery
... a less invasive hybrid technique for a difficult-to-treat defect in newborns known only one in the Tri-State area. as hypoplastic left heart syndrome (HLHS). To survive, babies born with this anomaly must undergo surgery in the first week of life. Until recently, the only treatment available was the ...
... a less invasive hybrid technique for a difficult-to-treat defect in newborns known only one in the Tri-State area. as hypoplastic left heart syndrome (HLHS). To survive, babies born with this anomaly must undergo surgery in the first week of life. Until recently, the only treatment available was the ...
The hemudynamic effects of ventrkuiar pacing with and
... effects of AV synchrony during exercise is limited by the difficulty of separating effects of atrial contraction from changes in ventricular rate and increases in myocardial contractility. Repeated measurements of cardiac performance during a single period of prolonged exercise or during serial exer ...
... effects of AV synchrony during exercise is limited by the difficulty of separating effects of atrial contraction from changes in ventricular rate and increases in myocardial contractility. Repeated measurements of cardiac performance during a single period of prolonged exercise or during serial exer ...
Prognostic Implications of Left Ventricular Mass and Geometry
... VALIANT study: age (in years), primary percutaneous transluminal coronary angioplasty, atrial fibrillation complicating MI, history of diabetes, history of hypertension, prior MI, Killip class, history of congestive heart failure, new left bundle branch block, history of angina, LVEF, estimated glom ...
... VALIANT study: age (in years), primary percutaneous transluminal coronary angioplasty, atrial fibrillation complicating MI, history of diabetes, history of hypertension, prior MI, Killip class, history of congestive heart failure, new left bundle branch block, history of angina, LVEF, estimated glom ...
Ellagic acid improved arrhythmias induced by CaCL2 in the rat
... Objective: In ventricular arrhythmias, due to their free radical scavenging action, antioxidant agents are usually used in the treatment of cardiovascular disease. Since stress is considered as risk factor for increased mortality by causing malignant arrhythmias, the study was designed to evaluate t ...
... Objective: In ventricular arrhythmias, due to their free radical scavenging action, antioxidant agents are usually used in the treatment of cardiovascular disease. Since stress is considered as risk factor for increased mortality by causing malignant arrhythmias, the study was designed to evaluate t ...
Standardized Definitions for End Point Events
... The purpose of this document is to provide a framework of definitions for cardiovascular end points in clinical trials. These definitions are based on clinical and research expertise, published guidelines and definitions, and our current understanding of the specific laboratory tests, diagnostic tes ...
... The purpose of this document is to provide a framework of definitions for cardiovascular end points in clinical trials. These definitions are based on clinical and research expertise, published guidelines and definitions, and our current understanding of the specific laboratory tests, diagnostic tes ...
Images and Case Reports in Arrhythmia and Electrophysiology
... occurred ⬎10 times a year and was associated with convulsion during exercise and emotionally exciting situations. The patient’s 13-year-old daughter had also experienced frequent episodes of syncope and developed ventricular fibrillation (VF) during treadmill exercise testing that was successfully d ...
... occurred ⬎10 times a year and was associated with convulsion during exercise and emotionally exciting situations. The patient’s 13-year-old daughter had also experienced frequent episodes of syncope and developed ventricular fibrillation (VF) during treadmill exercise testing that was successfully d ...
radiofrequency catheter ablation for supraventricular tachycardias
... cardiac disease is diagnosed, most of our treatments are palliative. Complaints may be diminished and life prolonged, but the disease process will not be stopped. Cure, however, is possible in the patient suffering from a tachycardia in an otherwise normal heart. Supraventricular type of tachyarrhyt ...
... cardiac disease is diagnosed, most of our treatments are palliative. Complaints may be diminished and life prolonged, but the disease process will not be stopped. Cure, however, is possible in the patient suffering from a tachycardia in an otherwise normal heart. Supraventricular type of tachyarrhyt ...
Hemodynamic and functional assessment of mechanical aortic
... METHODS: We performed a retrospective evaluation of 41 consecutive patients with AVR (27 bileaflet, 14 single disc) and both transthoracic echocardiography and 64-detector electrocardiographic-gated CT. Each study was interpreted by 2 independent, blinded readers. The effective orifice area was comp ...
... METHODS: We performed a retrospective evaluation of 41 consecutive patients with AVR (27 bileaflet, 14 single disc) and both transthoracic echocardiography and 64-detector electrocardiographic-gated CT. Each study was interpreted by 2 independent, blinded readers. The effective orifice area was comp ...
Utility of the Aspirin and P2Y12 Response Assays to Determine the
... long delays until results, prohibitively expensive equipment, or nonspecific results in the case of measuring thromboxane B2 and its metabolites.22,23 The ARU and PRU assays can be considered true point-of-care tests, given that they do not have these issues, although there is uncertainty over wheth ...
... long delays until results, prohibitively expensive equipment, or nonspecific results in the case of measuring thromboxane B2 and its metabolites.22,23 The ARU and PRU assays can be considered true point-of-care tests, given that they do not have these issues, although there is uncertainty over wheth ...
Assessment of left ventricle function in aortic stenosis: mitral annular
... despite progressive deterioration of the LV long-axis contractility [4-10]. Two-dimensional speckle tracking echocardiography (2D-STE) is an angle independent method that enables offline measurements of the longitudinal, radial and circumferential strain and strain rate [11-13]. 2D-STE derived globa ...
... despite progressive deterioration of the LV long-axis contractility [4-10]. Two-dimensional speckle tracking echocardiography (2D-STE) is an angle independent method that enables offline measurements of the longitudinal, radial and circumferential strain and strain rate [11-13]. 2D-STE derived globa ...
PE888 Supraventricular Tachycardia
... may allow fast electrical signals to get to the ventricles too quickly. This can cause a fast and irregular heart rhythm in the ventricles called ventricular fibrillation. Ventricular fibrillation caused by an accessory connection is very rare but can be dangerous and life threatening. Your child’s ...
... may allow fast electrical signals to get to the ventricles too quickly. This can cause a fast and irregular heart rhythm in the ventricles called ventricular fibrillation. Ventricular fibrillation caused by an accessory connection is very rare but can be dangerous and life threatening. Your child’s ...
Wide Complex Tachycardias - Texas Tech University Health
... One of the most common lethal errors made in arrhythmia diagnosis is to mistake VT for SVT and treat with verapamil, diltiazem, and adenosine, all of which can precipitate ventricular fibrillation in patients in VT, even if initially stable. Therefore, all wide-complex tachycardias should be assumed ...
... One of the most common lethal errors made in arrhythmia diagnosis is to mistake VT for SVT and treat with verapamil, diltiazem, and adenosine, all of which can precipitate ventricular fibrillation in patients in VT, even if initially stable. Therefore, all wide-complex tachycardias should be assumed ...
Congestive Heart Failure Survival Kit
... modifications that may improve their general well being. As well by controlling certain diseases, which contribute to HF, both symptoms and prognosis can be improved. These include: 1. Low salt diet – see no sodium diet (appendix a). General guidelines: • Prepare and cook all food without salt. Use ...
... modifications that may improve their general well being. As well by controlling certain diseases, which contribute to HF, both symptoms and prognosis can be improved. These include: 1. Low salt diet – see no sodium diet (appendix a). General guidelines: • Prepare and cook all food without salt. Use ...
Netherlands Heart Journal Supplements
... was reported. Results: 165 studies (122,721 patients) were included. A negative test result was associated with an overall pooled AER of 0.94% (0.81-1.09) ranging from 0.32% [0.22-0.43] for computed tomography angiography to 1.66% [1.22-2.16] for stress-echocardiography during 2.7 years follow-up. A ...
... was reported. Results: 165 studies (122,721 patients) were included. A negative test result was associated with an overall pooled AER of 0.94% (0.81-1.09) ranging from 0.32% [0.22-0.43] for computed tomography angiography to 1.66% [1.22-2.16] for stress-echocardiography during 2.7 years follow-up. A ...
Long-term time-course of nocturnal breathing disorders in heart failure patients
... [5, 15]. Segments with poor signal quality were discarded. Apnoeas and hypopnoeas were defined as, respectively, a .90% and a .50% reduction in VT lasting o10 s. The apnoea/ hypopnoea index (AHI) was computed as the number of apnoeas and hypopnoeas per hour. PB was defined as a sustained (o3 min) os ...
... [5, 15]. Segments with poor signal quality were discarded. Apnoeas and hypopnoeas were defined as, respectively, a .90% and a .50% reduction in VT lasting o10 s. The apnoea/ hypopnoea index (AHI) was computed as the number of apnoeas and hypopnoeas per hour. PB was defined as a sustained (o3 min) os ...
Cardiac Auscultation 101 - NC State Veterinary Medicine
... One of the keys to getting the most of your cardiac auscultation is proper understanding and use of your stethoscope. The main components of the stethoscope are the bell, diaphragm, tubing and earpieces. Many of the newer stethoscopes have the diaphragm and bell incorporated on the same side and one ...
... One of the keys to getting the most of your cardiac auscultation is proper understanding and use of your stethoscope. The main components of the stethoscope are the bell, diaphragm, tubing and earpieces. Many of the newer stethoscopes have the diaphragm and bell incorporated on the same side and one ...
Extracorporeal Membrane Oxygenation for Cardiac Failure
... diagnosed every year.5 The prognosis for heart failure patients is poor, with an average 1-year mortality rate of 33%.6 Several mechanical circulatory support devices are used for patients with heart failure. Included among these are extracorporeal membrane oxygenation (ECMO) and ventricular assist ...
... diagnosed every year.5 The prognosis for heart failure patients is poor, with an average 1-year mortality rate of 33%.6 Several mechanical circulatory support devices are used for patients with heart failure. Included among these are extracorporeal membrane oxygenation (ECMO) and ventricular assist ...
COX-2–Dependent Cardiac Failure in Gh/tTG Transgenic Mice
... disproportionately in older GhOEs. Cardiomyocyte expression of COX-2, thromboxane synthase (TxS), and the receptors for TxA2 (the TP), PGF2␣ (the FP), and PGI2 (the IP) were upregulated and urinary 8,12-iso-iPF2␣-VI,2,3dinor-6-keto-PGF1␣ and 2,3-dinor-thromboxane B2 were increased in GhOEs, reflecti ...
... disproportionately in older GhOEs. Cardiomyocyte expression of COX-2, thromboxane synthase (TxS), and the receptors for TxA2 (the TP), PGF2␣ (the FP), and PGI2 (the IP) were upregulated and urinary 8,12-iso-iPF2␣-VI,2,3dinor-6-keto-PGF1␣ and 2,3-dinor-thromboxane B2 were increased in GhOEs, reflecti ...
Document
... Introduction: The product of heart rate and systolic blood pressure, termed as rate-pressure product (RPP), is a very reliable indicator of myocardial oxygen demand and is widely used clinically. There have been previous attempts to describe the relationship between RPP and the onset of pain in angi ...
... Introduction: The product of heart rate and systolic blood pressure, termed as rate-pressure product (RPP), is a very reliable indicator of myocardial oxygen demand and is widely used clinically. There have been previous attempts to describe the relationship between RPP and the onset of pain in angi ...
Murine conduction system development
... corresponding to the looped heart stage, the apex of the ventricle is activated earlier than ventricular myocardium closer to the atrioventricular canal (de Jong et al., 1992). However, using similar extracellular recording techniques, Chuck et al., found this transition to occur between H/H stages ...
... corresponding to the looped heart stage, the apex of the ventricle is activated earlier than ventricular myocardium closer to the atrioventricular canal (de Jong et al., 1992). However, using similar extracellular recording techniques, Chuck et al., found this transition to occur between H/H stages ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.