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Echocardiographic Assessment of Ventricular Systolic Function
Echocardiographic Assessment of Ventricular Systolic Function

... 15%. The apical septal and apical inferior segments were aneurysmal. The entire anterior wall, mid- and distal lateral walls, anterior septal, midposterior segment, midseptal segments, midinferior segment, and basal septal segments were akinetic. The basal lateral and basal inferior segments were hy ...
Human Heart Weight at High Altitude
Human Heart Weight at High Altitude

... continental United States revealed that right ventricular hypertrophy is no greater at high altitude than at sea level in the stillborn-newborn infant heart. Right ventricular weight relative to total heart weight at high altitude exceeds that at sea level beginning about 30 days after birth and rea ...
Phenotyping transgenic embryonic murine hearts using optical
Phenotyping transgenic embryonic murine hearts using optical

... HEXIM1 ⫺兾⫺ mice were created with an insertional mutation in the HEXIM1 gene that disrupts the C-terminal region. A mouse embryonic stem cell line XB322, which contained an insertional mutation in HEXIM1, was injected into C57BL兾6 blastocysts. The blastocysts resulted in two chimeric male mice that ...
Ventricular Dysrhythmias Learning Outcomes 9.1 Describe the various
Ventricular Dysrhythmias Learning Outcomes 9.1 Describe the various

... 9.4 Identify idioventricular rhythm using the criteria for classification, and explain how the rhythm may affect the patient, including basic patient care and treatment. 9.5 Identify accelerated idioventricular rhythm using the criteria for classification, and explain how the rhythm may affect the p ...
Accelerated idioventricular rhythm observed under total intravenous
Accelerated idioventricular rhythm observed under total intravenous

... causes for the event. The adverse event appeared after their administration (+2). The adverse event improved when they were discontinued (+1). The reaction was less severe when their doses were decreased (+1), because the surgery 1 year prior had no episode of an AIVR with balanced anesthesia using ...
8 Heart Murmurs Part II
8 Heart Murmurs Part II

... low-frequency diastolic murmur. The murmur will sound quite similar to the diastolic rumble of mitral stenosis and is best heard at the apex. This is called the Austin Flint murmur (4,22–26). That the Austin Flint murmur is a sign of severe aortic regurgitation can in fact be proven by improving for ...
Does This Patient Have Aortic Regurgitation?
Does This Patient Have Aortic Regurgitation?

... is unsure whether a murmur represents PR or AR, then these maneuvers may help distinguish between the 2. In this latter situation, the clinician should listen where the murmur is just barely audible, so that it is easy to detect a decrease or increase in murmur intensity during the maneuver. Quiet i ...
Muscular Ventricular Septal Defects" A Reappraisalof the Anatomy
Muscular Ventricular Septal Defects" A Reappraisalof the Anatomy

... 3): There were eight hearts with this anomaly. This type of defect is sometimes multi~)le, it is always close to the ventricular wail, but it may be distributed ailalong the septal margins. Thus, it can be found anterior to the trabecula septomarginalis, at the very apex of the heart, or posterior t ...
Left Ventricular Remodeling in Heart Failure
Left Ventricular Remodeling in Heart Failure

... compared with that of heart failure and the overall composite end point, suggests that the mechanisms responsible for adverse outcomes are not simply operating through cardiac dysfunction and clinical heart failure. Rather, it is likely that LV remodeling represents a more global biomarker of system ...
Cyanotic Heart Disease
Cyanotic Heart Disease

... Corrected Transposition (L-Trans) Inversion of the Ventricles with Transposition of the Great Vessels ...
Normal Sinus Rhythm
Normal Sinus Rhythm

... • VT can range in rate from 100-300bpm and the patient may be conscious and asymptomatic, symptomatic, or unconscious. Treatment will depend principally on the patients’ clinical status. © Hayley Coxon 2014 ...
Left Ventricular Systolic Function is Sensitive to Cycle
Left Ventricular Systolic Function is Sensitive to Cycle

... Patients The study population was comprised of consecutive patients with chronic AF who were referred for echocardiographic examination between August 2005 and July 2006. Patients with poor quality echocardiographic images, frequent ventricular premature beats, complete atrioventricular block, mitra ...
Instantaneous pressure gradient across the aortic valve
Instantaneous pressure gradient across the aortic valve

... Abstract Aortic stenosis is the most frequent valvular heart disease. The mean systolic value of the transvalvular pressure gradient (TPG) is commonly utilized during clinical examination to evaluate its severity and it can be determined either by cardiac catheterization or by Doppler echocardiograp ...
Systemic vascular resistance: an unreliable index of left
Systemic vascular resistance: an unreliable index of left

... of the myocardium becomes critically important in interpreting variables of left ventricular shortening in patients suspected of having contractile abnormalities. 1-3 In the clinical setting, the most commonly used measure of ventricular afterload is systemic vascular resistance (SVR). However, SVR ...
The outcomes of operations for 539 patients with Ebstein anomaly
The outcomes of operations for 539 patients with Ebstein anomaly

... TVrpl, branch pulmonary artery enlargement, emergency opening of the chest in the ICU, a miscellaneous arrhythmia procedure (cryoablation, left-sided maze procedure, or ligation of the left atrial appendage), and postoperative need for mechanical cardiac support were associated with higher mortality ...
Tissue Heart Valve Replacement at BSMMU
Tissue Heart Valve Replacement at BSMMU

... The main problems with bioprosthetic valves are structural failure from early calcification particularly in younger age group; Children exhibit the highest incidence of primary tissue failure because of increased uptake of calcium and high calcium metabolism. For children, tissue valve durability ge ...
Search for: 10 or 12
Search for: 10 or 12

... As a physician, coach, or trainer, we see athletes as healthy, physically fit, and able to tolerate extremes of physical endurance. It seems improbable that such athletes may have, on occasion, underlying life-threatening cardiovascular abnormalities. Regular physical activity promulgates cardiovasc ...
Myocardial infarction: redefined or reinvented? - Heart
Myocardial infarction: redefined or reinvented? - Heart

... studies of the value of troponins across the whole spectrum of acute coronary disease. Such studies should include standardisation of the two different assays and assessment of false positive elevations caused by other cardiac conditions and the confounding effect of renal failure. Comparisons of th ...
Selection of patients for cardiac transplantation
Selection of patients for cardiac transplantation

... transplantation based on etiology were: cardiomyopathy 72% 1 year, 67% 5 years; coronary artery disease 70% 1 year, 63% 5 years; congenital heart disease 64% 1 year, 62% 5 years; and graft rejection 47% 1 year, 47% 5 years. Limited prognosis is the common characteristic among all etiologic groups be ...
endomyocardial fibrosis
endomyocardial fibrosis

... Seven southern districts of Kerala with (a) areas of high density of occurrence of endomyocardial fibrosis (EMF) (b) areas with deposits of ...
Differential Effects of Antihypertensive Treatment on Left Ventricular
Differential Effects of Antihypertensive Treatment on Left Ventricular

... preserved systolic function. This accounts for approximately one-third to one-half of heart failure cases (2,3), and most of these patients have a history of hypertension (1), often with LV hypertrophy and remodeling (4 – 8). While many studies have focused on the effectiveness of hypertension treat ...
Pharmacology Review - Madison County Emergency Medical District
Pharmacology Review - Madison County Emergency Medical District

... Repeat after 2 minutes if necessary Acute Coronary Syndromes ...
Intrinsic changes on automatism, conduction, and refractoriness by
Intrinsic changes on automatism, conduction, and refractoriness by

... each stimulation period the train frequency was increased by 40 beats/min. Several trains were used until the maximum frequency with auricular capture was reached. The pause between two consecutive trains was 30 s. 2) Atrial stimulation with a short train of eight stimuli at a rate slightly higher t ...
Lipomatous Hypertrophy of the Interatrial Septum
Lipomatous Hypertrophy of the Interatrial Septum

... with lipomatous hypertrophy of the interatrial septum have a high body mass index level (>30).8 Our case also occurred in a non-obese middle-aged man. Although it is an asymtomatic benign tumor in most cases, the case may be associated with atrial arrythmias, congestive heart failure, recurrent peri ...
Intrinsic changes on automatism, conduction
Intrinsic changes on automatism, conduction

... each stimulation period the train frequency was increased by 40 beats/min. Several trains were used until the maximum frequency with auricular capture was reached. The pause between two consecutive trains was 30 s. 2) Atrial stimulation with a short train of eight stimuli at a rate slightly higher t ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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