Dilated cardiomyopathy in mice deficient for the lysosomal cysteine
... of echocardiography, a CTSL-genotype-dependent increase of left ventricular dimensions was observed in 1-year-old mice (Fig. 4). Again, four of the 14 ctsl⫺/⫺ mice investigated by echocardiography exhibited a severe enlargement of the left ventricle with a 2- to 3-fold increase in the volumes of the ...
... of echocardiography, a CTSL-genotype-dependent increase of left ventricular dimensions was observed in 1-year-old mice (Fig. 4). Again, four of the 14 ctsl⫺/⫺ mice investigated by echocardiography exhibited a severe enlargement of the left ventricle with a 2- to 3-fold increase in the volumes of the ...
Tachycardia-induced cardiomyopathy in children and
... reversible condition with effective treatment of tachycardia. These patients may be misdiagnosed, potentially leading to inappropriate treatment. Diagnosis is often late and always should be suspected in patients with congestive heart failure and unexplained persistent tachycardia. Case reports. We ...
... reversible condition with effective treatment of tachycardia. These patients may be misdiagnosed, potentially leading to inappropriate treatment. Diagnosis is often late and always should be suspected in patients with congestive heart failure and unexplained persistent tachycardia. Case reports. We ...
Slide 1
... If the patient is not pacemaker dependent, an asynchronous mode will compete with the intrinsic rhythm. Some types of pacemakers, application of a magnetic field is a step required to initiate reprogramming of the generator. Random reprogramming when exposed to magnetic ...
... If the patient is not pacemaker dependent, an asynchronous mode will compete with the intrinsic rhythm. Some types of pacemakers, application of a magnetic field is a step required to initiate reprogramming of the generator. Random reprogramming when exposed to magnetic ...
How to use echo-Doppler in clinical trials: different modalities for
... not sufficient but should be combined with the demonstration that modifications of the echo-Doppler measurements correspond (better if proportionally) to changes in outcome events. At present, regulatory authorities do not consider echo-Doppler parameters as endpoints in pivotal trials designed to p ...
... not sufficient but should be combined with the demonstration that modifications of the echo-Doppler measurements correspond (better if proportionally) to changes in outcome events. At present, regulatory authorities do not consider echo-Doppler parameters as endpoints in pivotal trials designed to p ...
The index of suspicion of RV infarction should be particularly high in
... Pulsed Doppler at the tip of the mitral leaflets in the apical 4chamber view. Note E and A velocities, and E deceleration time ...
... Pulsed Doppler at the tip of the mitral leaflets in the apical 4chamber view. Note E and A velocities, and E deceleration time ...
A Novel Method for Cine-CMR Automated Assessment of Left
... Biomedical Engineering, Cornell University, Ithaca, New York, United States, 2Radiology, Weill Cornell Medical College, New York, New York, United States, ...
... Biomedical Engineering, Cornell University, Ithaca, New York, United States, 2Radiology, Weill Cornell Medical College, New York, New York, United States, ...
Aortic stiffness and valvular calcifications in patients with end
... Abstract: Objectives. To evaluate the presence and extent of cardiac calcifications and aortic stiffness in patients with end-stage renal disease (ESRD). Patients and methods. The study group consisted of 60 patients with ESRD with a mean age of 51.7 years, treated with peritoneal dialysis. In all p ...
... Abstract: Objectives. To evaluate the presence and extent of cardiac calcifications and aortic stiffness in patients with end-stage renal disease (ESRD). Patients and methods. The study group consisted of 60 patients with ESRD with a mean age of 51.7 years, treated with peritoneal dialysis. In all p ...
Developmental anatomy of the heart: a tale of
... plug is observed as embryonic day 0.5 (ED0.5 ; Ref. 34). Others, however, will consider this ED1.0. This obviously can lead to confusion, and more importantly, misinterpretation of data. Thus, when describing and comparing developmental events, it is very important to be very explicit about the stag ...
... plug is observed as embryonic day 0.5 (ED0.5 ; Ref. 34). Others, however, will consider this ED1.0. This obviously can lead to confusion, and more importantly, misinterpretation of data. Thus, when describing and comparing developmental events, it is very important to be very explicit about the stag ...
Risk of Ventricular Arrhythmia After Implantable Defibrillator
... shocks, which were delivered for ventricular tachycardia or ventricular fibrillation. Patients visited the center of implantation at regular intervals (mostly 3 or 6 months). During these visits arrhythmic events were recorded from the ICD and stored. Only a small number of patients did not visit th ...
... shocks, which were delivered for ventricular tachycardia or ventricular fibrillation. Patients visited the center of implantation at regular intervals (mostly 3 or 6 months). During these visits arrhythmic events were recorded from the ICD and stored. Only a small number of patients did not visit th ...
Acute Dyspnea in the Office - American Academy of Family Physicians
... coexisting cardiac and pulmonary symptoms. Cardiac and pulmonary problems are the most common causes of dyspnea. Determine onset, duration, and occurrence at rest or exertion. The presence of cough may imply asthma or pneumonia; cough combined with a change in the character of sputum may be caused b ...
... coexisting cardiac and pulmonary symptoms. Cardiac and pulmonary problems are the most common causes of dyspnea. Determine onset, duration, and occurrence at rest or exertion. The presence of cough may imply asthma or pneumonia; cough combined with a change in the character of sputum may be caused b ...
this PDF file
... Peter S. ECG features of ARVD/C A very good option is describe arrhyhmogenic cardiomyopathy by ECG is the appearance of so-called epsilon waves[2,7]. Epsilon waves are major criteria in the definition of arrhythmogenic cardiomyopathy very well characterising conduction delay of the right ventricle. ...
... Peter S. ECG features of ARVD/C A very good option is describe arrhyhmogenic cardiomyopathy by ECG is the appearance of so-called epsilon waves[2,7]. Epsilon waves are major criteria in the definition of arrhythmogenic cardiomyopathy very well characterising conduction delay of the right ventricle. ...
efficacy of thrombolytic therapy in preserving left ventricular function
... infarct related artery and its consequent effect on left ventricular function. At total of 48 patients were investigated, all presenting with symptoms of chest pain. Clinical, electrocardiography and echocardiographic criteria were used to document myocardial infarction. 2-D and M-mode echocardiogra ...
... infarct related artery and its consequent effect on left ventricular function. At total of 48 patients were investigated, all presenting with symptoms of chest pain. Clinical, electrocardiography and echocardiographic criteria were used to document myocardial infarction. 2-D and M-mode echocardiogra ...
Electroanatomical Mapping Systems and Cardiac Arrhythmias
... care unit, with an incidence of 19%. Between them tachyarrhythmias occur more rarely, with an incidence of 2% [2]. Their incidence is greater in children older than 1 year and in patients with grown-up congenital heart diseases [3]. Between all arrhythmias the supraventricular tachycardias are the m ...
... care unit, with an incidence of 19%. Between them tachyarrhythmias occur more rarely, with an incidence of 2% [2]. Their incidence is greater in children older than 1 year and in patients with grown-up congenital heart diseases [3]. Between all arrhythmias the supraventricular tachycardias are the m ...
Simulation of Aortic Valve Replacement Surgery Hadi Mohammadi
... valve replacement may avoid early and late fatal events and result in improved functional status. Early diagnosis and treatment will preserveregular ventricular function or may return irregular function to regular. ...
... valve replacement may avoid early and late fatal events and result in improved functional status. Early diagnosis and treatment will preserveregular ventricular function or may return irregular function to regular. ...
Morphological and Functional Modeling of the Heart Valves and
... techniques, bioprosthetic valves, robotic surgery and percutaneous interventions, which have led to a twofold increase in the number of valve procedures performed in the United States since 1985 (Jablokow (2009)). There has been a major trend in cardiac therapy towards minimally invasive transcathet ...
... techniques, bioprosthetic valves, robotic surgery and percutaneous interventions, which have led to a twofold increase in the number of valve procedures performed in the United States since 1985 (Jablokow (2009)). There has been a major trend in cardiac therapy towards minimally invasive transcathet ...
development of interatrial and interventricular septum
... Defects in the inferior/anterior atrial septum region that includes the coronary sinus orifice. ...
... Defects in the inferior/anterior atrial septum region that includes the coronary sinus orifice. ...
Sudden Cardiac Death in the Young
... Worldwide, the overall incidence of SCD is estimated at 0.93/100,000 in Sweden from 1992-1999 3 and 1.47/100,000 in Iceland. Behr et al estimate the incidence of Sudden Arrhythmic Death Syndrome or SADS in England, using prospective case reviews from 1997-1999, at 0.16 per 100,000 persons per year4 ...
... Worldwide, the overall incidence of SCD is estimated at 0.93/100,000 in Sweden from 1992-1999 3 and 1.47/100,000 in Iceland. Behr et al estimate the incidence of Sudden Arrhythmic Death Syndrome or SADS in England, using prospective case reviews from 1997-1999, at 0.16 per 100,000 persons per year4 ...
The Mechanics of Left Ventricular Contraction in Acute
... except in Figure 5, where active tension (developed tension minus resting tension) is also shown for comparison. VcE, myocardial wall tension, contractile element power, and contractile element work were also determined at 10-msec intervals during auxotonic contractions; as previously, VCE during ej ...
... except in Figure 5, where active tension (developed tension minus resting tension) is also shown for comparison. VcE, myocardial wall tension, contractile element power, and contractile element work were also determined at 10-msec intervals during auxotonic contractions; as previously, VCE during ej ...
Assessment and consequences of the constant-volume - AJP
... the constant-volume attribute in humans due to technological limitations of X-ray imaging in conjunction with anatomic differences between dogs and humans (11). Later studies used magnetic resonance (MR) imaging (MRI) to evaluate pericardial volume in humans at several discrete timepoints (9–11) and ...
... the constant-volume attribute in humans due to technological limitations of X-ray imaging in conjunction with anatomic differences between dogs and humans (11). Later studies used magnetic resonance (MR) imaging (MRI) to evaluate pericardial volume in humans at several discrete timepoints (9–11) and ...
Downloaded - OSU CCME account
... magnetic resonance (CMR) late gadolinium enhancement technique. Currently, quantifying diffuse myocardial fibrosis requires invasive biopsy, with inherent risk and sampling error. We have developed a robust and noninvasive technique, equilibrium contrast CMR (EQ–CMR) to quantify diffuse fibrosis and ...
... magnetic resonance (CMR) late gadolinium enhancement technique. Currently, quantifying diffuse myocardial fibrosis requires invasive biopsy, with inherent risk and sampling error. We have developed a robust and noninvasive technique, equilibrium contrast CMR (EQ–CMR) to quantify diffuse fibrosis and ...
Association between left ventricular hypertrophy
... hypertension (HTN) is associated with certain target organ damage (TOD) and related clinical conditions. On the other hand, left ventricular ...
... hypertension (HTN) is associated with certain target organ damage (TOD) and related clinical conditions. On the other hand, left ventricular ...
The correlation between ventricular remodeling and arrhythmia in
... ventricular myocardial area (LVMA), and function over time can be used to predict ventricular arrhythmias after infarction [4]. According to the philosophical principle that the material structure decides its function, it is plausible that changes of cardiac electrophysiological properties reflect t ...
... ventricular myocardial area (LVMA), and function over time can be used to predict ventricular arrhythmias after infarction [4]. According to the philosophical principle that the material structure decides its function, it is plausible that changes of cardiac electrophysiological properties reflect t ...
Left Ventricle
... superior corner of atrium • Opens into right ventricle via tricuspid valve (right atrioventricular valve) © 2014 Pearson Education, Inc. ...
... superior corner of atrium • Opens into right ventricle via tricuspid valve (right atrioventricular valve) © 2014 Pearson Education, Inc. ...
Double Orifice Mitral Valve and Bicuspid Aortic Valve: Pieces of the
... of the functional status revealed NYHA class III dyspnea. Vitals were normal. Levine 3/6 apical diastolic murmur was noted in auscultation. ECG, chest X-ray, and routine blood work yielded normal results. Transthoracic echocardiography clearly showed the mitral valve with 2 separate orifices. The gr ...
... of the functional status revealed NYHA class III dyspnea. Vitals were normal. Levine 3/6 apical diastolic murmur was noted in auscultation. ECG, chest X-ray, and routine blood work yielded normal results. Transthoracic echocardiography clearly showed the mitral valve with 2 separate orifices. The gr ...
Hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.