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CR 10: Myocarditis mimicking an acute coronary syndrome
CR 10: Myocarditis mimicking an acute coronary syndrome

... acute coronary syndrome was considered. • The patient received anti-ischemic treatment. ...
Cardiac Cycle: End Systole
Cardiac Cycle: End Systole

... – Supine: End-diast. volume is increased-> increased stroke-volume • Any outflow murmur that is dependent the amount of flow will be louder supine ...
Noncompaction of the ventricular myocardium with bicuspid aortic
Noncompaction of the ventricular myocardium with bicuspid aortic

... are used to diagnostic echocardiographic criteria. Noncompacted to compacted layer ratio calculated at the level of the papillary muscles was 2.6 in the patient presented in this report. Magnetic resonance imaging, computed tomography and ventriculography can also be useful imaging modalities (5). H ...
Severe aortic stenosis in a Persian kitten Estenose aórtica
Severe aortic stenosis in a Persian kitten Estenose aórtica

... the owner was informed of the possibility of starting a beta-adrenergic receptor blocking drug and an angiotensin-converting enzyme inhibitor empirically (Kienle, 1998; Sisson et al., 2000; Belerenian, 2007), since a severely increased gradient was measured across aortic valve. By decreasing heart r ...
PDF - Circulation
PDF - Circulation

... rabbits is the perinatal fatality in lines that mutant cTnIG146 comprised ⬎40% of the total myofibrillar cTnI.9 The finding is in apparent dichotomy with human HCM, whereby the affected individuals, having 1 mutant and 1 wild-type allele, are expected to express equal levels of the mutant and wild-t ...
Surgical Considerations of LVAD Implantation in
Surgical Considerations of LVAD Implantation in

... shortened opening time. Mechanical aortic valves are highly susceptible to thrombosis in this environment, and intermittent opening of the valve increases the risk of thromboembolism. Patients with preexisting mechanical aortic valves should have the valve oversewn or replaced with a bioprosthetic a ...
Left ventricular noncompaction: clinical
Left ventricular noncompaction: clinical

... (ejection fraction 30%). The next patient had prolapse of the anterior mitral leaflet with enlarged left ventricle dimensions and still not impaired systolic function (Figure 1C). These two patients had atrial fibrillation at the beginning. According to the guidelines for valvular heart disease, 3 p ...
Nesiritide Use at the Texas Children`s Hospital
Nesiritide Use at the Texas Children`s Hospital

... “Heart failure is a complex clinical syndrome that can result from any structural or functional cardiac disorder that impairs the ability of the ventricle to fill with or eject blood.” ...
Interventricular Septum Rupture in the Catheterization Laboratory
Interventricular Septum Rupture in the Catheterization Laboratory

... with definitive coronary artery bypass graft surgery within 24-72 hours. Due to persistent hypotension, an intra-aortic balloon pump was placed with good diastolic augmentation. ...
The Cardiac Pump
The Cardiac Pump

... Therefore, stress=TP x R/2w Afterload represents all the factors that contribute to total myocardial wall stress (or tension) during systolic ejection. Arterial pressure and TPR contribute to afterload but should not be equated with afterload. ...
A1985ABD9400001
A1985ABD9400001

... pathophysiological rationale for this therapeutic approach. However, prevailing thinking at the time held that lowering of blood pressure in acute myocardial infarction was dangerous and to be avoided, In fact, the use of nitroglycerin was felt to be contraindicated in the face of established ...
Hammock Bridge on Fire: Complete AV Block in a Patient
Hammock Bridge on Fire: Complete AV Block in a Patient

... Aims: To recognize heart block as a complication associated with congenitally-corrected transposition of the great arteries (CCTGA). Presentation of the Case: A healthy 36 year old male with CCTGA presented with syncope as a manifestation of heart block. A unique feature of this case was the presenc ...
The Dilemma of Genotype Positive
The Dilemma of Genotype Positive

... thickness. Postdeconditioning echocardiograms demonstrating no change in LV wall thickness are therefore more suspicious for HCM versus athlete’s heart. Family Screening HCM has been associated with more than 1,400 mutations (10,14) in 13 sarcomere genes (21). Many of these mutations are considered ...
congenital defects: tetralogy of fallot
congenital defects: tetralogy of fallot

... but bulldogs and cats have increased incidence as well. ...
Reduced LVEF with Symptoms
Reduced LVEF with Symptoms

... • These agents show a significant decrease in the mortality and morbidity. • May be considered as a single-agent therapy in patients who have mild dyspnea on excursion, and do not have signs of volume overload. • Early use of these ACE Inhibitors Indicated in patient with all stages of left ventricu ...
Q1 March 2009 Relate the surface ECG to the events of the cardiac
Q1 March 2009 Relate the surface ECG to the events of the cardiac

... Begins with the p wave, which represents electrical depolarisation of the atria. PR interval (normal duration 0.12-0.2s) includes conduction through the AV node. Last phase of diastole. Phase 2 - Isovolumetric contraction Begins with the QRS cycle, which represents ventricular depolarisation. Peak o ...
The Cardiac Cycle:
The Cardiac Cycle:

... relaxation. Valve closure is associated with a small backflow of blood into the ventricles and a characteristic notch (dicrotic notch) in the aortic and pulmonary artery pressure tracings. Although ventricular pressures decrease during this phase, volumes remain constant because all valves are close ...
Restrictive Cardiomyopathy (RCM)
Restrictive Cardiomyopathy (RCM)

... function. RCM can be caused by a change or mutation in a gene that encodes proteins important for the contraction or squeeze of the heart muscle. Most often, RCM is inherited. A parent that carries a gene mutation will have a 50 percent chance of passing it on to each child. Genetic testing is avail ...
study notes for test
study notes for test

... Systolic blood pressure (the upper number) — indicates how much pressure your blood is exerting against your artery walls when the heart beats. Diastolic blood pressure (the lower number) — indicates how much pressure your blood is exerting against your artery walls while the heart is resting betwee ...
Heart 2 PPT
Heart 2 PPT

... prevents tetanus contractions and is due to the opening of Ltype Calcium channels. It allows the heart to relax and fill with blood again before the next contraction. Opening of the L-type Calcium channels provides the prolonged depolarization plateau, due to an influx of Calcium in to the myocardia ...
Atrial Septal Defect
Atrial Septal Defect

... The atria are the upper chambers of the heart. The septum is a wall that separates the left and right sides of the heart. An atrial septal defect means there is a hole in the septum (wall). When this occurs, there is an abnormal communication between the left and the right sides of the heart. This t ...
Sample Exam 3
Sample Exam 3

... c. chordae tendineae d. Bundle of His e. atrioventricular node 15. A condition in which the heart rate is less than 60 per minute is known as ____________. a. tachycardia b. bradycardia c. atrial fibrillation d. ventricular diastole e. atrial repolarization 16. Which of the following sequences descr ...
Ventricular tachycardia
Ventricular tachycardia

... Exclusion of all conditions leading to VT or VF ...
Primary left atrial angiosarcoma mimicking severe mitral valve stenosis
Primary left atrial angiosarcoma mimicking severe mitral valve stenosis

... of the malignant tumour is angiosarcoma. However, until 1995 fewer than 200 cases had been reported in the English language literature.6 Angiosarcomas almost always originate in the right atrium and are associated with dyspnoea, thoracic pain, general fatigue, or symptoms of right heart failure. How ...
Powerpoint 19 Heart - People Server at UNCW
Powerpoint 19 Heart - People Server at UNCW

... The pressure developed within a heart chamber is related to two things. 1. volume of blood within the chamber 2. size of the chamber ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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