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28 Ejection Clicks
28 Ejection Clicks

... being very responsive to changes in ventricular volume induced by posture or pharmacologic agents . Originally these nonejection clicks were thought to be extracardiac, but Barlow and subsequently others have clearly demonstrated their cardiac origin . Mitral and tricuspid clicks usually move to an ...
Cardiac sympathetic activity in chronic heart failure: cardiac 123I
Cardiac sympathetic activity in chronic heart failure: cardiac 123I

... Cardiac sympathetic hyperactivity is reflected by a decreased 123I-mIBG late H/M ratio and increased WO. Both are associated with increased fatal arrhythmia and cardiac mortality. It has been reported that late H/M ratio < 1.6 is associated with poor outcome [29]. However, meta-analyses showed that ...
Summary
Summary

... and derived stroke volume variation (SVV), as well as systolic and pulse pressure variations predict changes in bolus thermodilution cardiac output (COtd), induced by continuous and cyclic increases in intrathoracic pressures by increases in positive end-expiratory pressure (PEEP) and tidal volume ( ...
Oh-no-the-heart-failure-cat
Oh-no-the-heart-failure-cat

... grade 4 murmur at a heart rate of 180 or 190. That is very classical for this disease. So this is what we call a dynamic murmur and it can be very difficult for owners to appreciate that their cat may have a murmur on some days and it may not have a murmur on others depending on its level of stress ...
Effects of the HeartMate II continuous
Effects of the HeartMate II continuous

... identified as female gender, nonischemic heart failure etiology, increased right atrial pressure, low pulmonary artery pressure, and decreased RV stroke work index (RVSWI). Others have identified abnormal biochemical indicators such as elevated levels of bilirubin, creatinine, and aspartate aminotra ...
ACLS Guidelines 2015 Update
ACLS Guidelines 2015 Update

... The guidelines suggest a compression to breath ratio of 30:2, however in Seattle, the survival rates for cardiac arrest overall have remained around 19-20%, and for Ventricular Fibrillation are 44%, the highest in the world, possible, in part due to a revision of the compression to breaths ratio. Ra ...
Indications for ICDs
Indications for ICDs

... cardiac arrest and after evaluation of the event it is found not attributable to reversible causes ○ Patients with congenital heart disease and spontaneous sustained VT should undergo invasive hemodynamic and EP evaluation • Catheter ablation or surgical resection to address VT • If that does not wo ...
Print - Circulation Research
Print - Circulation Research

... to overcome both these limitations by allowing noninvasive characterization of cardiac tissue structure.25,26 In this technique, a tensor that represents the 3D diffusion of water in each image voxel is estimated. The primary eigenvector of this tensor points in the direction in which the rate of di ...
Aortic valve sclerosis and cardiac calcification.
Aortic valve sclerosis and cardiac calcification.

... • A number of prospective and retrospective studies have established that AVS is an independent, incremental risk marker of mortality and cardiovascular events. • It is largely accepted that the pathogenesis of AVS shares many features with the atherosclerotic process in several vascular beds. • Oth ...
Should all patients receive dual chamber pacing ICDs? The
Should all patients receive dual chamber pacing ICDs? The

... All of the prospective multicenter trials that support the use of implantable defibrillators have used single chamber pacemakers/implantable cardiovertor defibrillators (ICDs). Despite the significantly increased cost of dual chamber pacemaker/ICD devices and the lack of outcome data, these devices ...
Wall Thickness and Diastolic Properties of the Left Ventricle
Wall Thickness and Diastolic Properties of the Left Ventricle

... from the present data that within the population of all patients exhibiting LVH by ECG criteria, wall thickness acts as a further and independent predictor of stiffness. This is supported by the observation that even in the absence of LVH, increased h1, was associated with increased S, as noted in p ...
A Novel Noninvasive Device to Assess Sympathetic Nervous
A Novel Noninvasive Device to Assess Sympathetic Nervous

... cardiography. Ambulatory assessment of hemodynamic and sympathetic nervous system function using impedance cardiography has been used to measure cardiovascular reactivity in persons with a family history of cardiovascular disease (Wright, O’Donnell, Brydon, Wardle, & Steptoe, 2007) and hypertension ...
The Mural Left Anterior Descending Coronary Artery,
The Mural Left Anterior Descending Coronary Artery,

... These unheralded deaths in three active persons without family history of cardiac disease or sudden death and with coronary arteries unobstructed by atherosclerosis had four common features: (1) collapse and death incidental to strenuous exercise, (2) mural LAD artery, (3) underdeveloped or reduced ...
Dobutamine stress echo-induced apical ballooning (Takotsubo
Dobutamine stress echo-induced apical ballooning (Takotsubo

... Epicardial coronary spasm has been demonstrated in up to 11% of reported cases. Provoked spasm has been demonstrated in the catheterization laboratory, but its relevance remains unclear. Microvascular spasm and microvascular obstruction have been hypothesized, but the lack of subendocardial infarcti ...
Adult Heart Murmurs - American Academy of Family Physicians
Adult Heart Murmurs - American Academy of Family Physicians

... The material presented here is being made available by the American Academy of Family Physicians for educational purposes only. This material is not intended to represent the only, nor necessarily best, methods or procedures appropriate for the medical situations discussed. Rather, it is intended to ...
Silent and Malignant Early Repolarization Syndrome Mimicking
Silent and Malignant Early Repolarization Syndrome Mimicking

... manifests in the lateral precordial leads, often occurs in healthy athletes, and is associated with a lowest risk of arrhythmia. Type 2 simultaneously manifests in the inferior and inferior-lateral leads, and is associated with a moderate risk. An early repolarization pattern existing in inferior, l ...
transesophageal echocardiography
transesophageal echocardiography

... region to be measured (fig 4). A single crystal is used to transmit an ultrasound signal and then to receive after a pre-set time delay. There is a limit to the maximaum velocity that can be accurately detected, before a phenomenon known as ‘aliasing’ occurs usually at velocities in excess of 2 m/s ...
Characterization of Suitability of Coronary Venous Anatomy for
Characterization of Suitability of Coronary Venous Anatomy for

... the maximal dyssynchrony site translates into an improved clinical outcome, as well as reduced mortality and heart failure hospitalizations.9 One of the main restricting factors of the LV lead placement is the variability in the coronary venous anatomy. Some previous invasive studies have shown the ...
Document
Document

... This kind of rhythm is present in up to 5% of adult population, mostly in older age. It is often connected with other diseases of the heart (ischaemic haert disease, heart failure. Atrial fibrillation is important because it can lead to: ...
Myocardial High Energy Phosphate Stores in Cardiac Hypertrophy
Myocardial High Energy Phosphate Stores in Cardiac Hypertrophy

... (CP) and adenosine triphosphate (ATP) were determined in samples removed from the right ventricles of these animals during life and in papillary muscles isolated from these same hearts. The papillary muscles from the cats with hypertrophy and failure exhibited depressed intrinsic contractility. The ...
PAthoPhySIology of hEARt fAIluRE - The Association of Physicians
PAthoPhySIology of hEARt fAIluRE - The Association of Physicians

... are present. Radiologically, chest x-ray findings may reveal cephalization of blood flow, interstitial edema, perihilar edema and then alveolar edema. Whitening of lungs is noted with increasing severity of pulmonary venous hypertension. ...
Impact of Atrioventricular Compliance on Pulmonary Artery Pressure
Impact of Atrioventricular Compliance on Pulmonary Artery Pressure

... Background—The decay of the pressure gradient across a stenotic mitral valve is determined by the size of the orifice and net AV compliance (Cn). We have observed a group of symptomatic patients, usually in sinus rhythm, characterized by pulmonary hypertension (particularly during exercise) despite ...
GREEN Form - AHP Diet Drug Settlement
GREEN Form - AHP Diet Drug Settlement

... Part I of this form identifies an individual who was prescribed and ingested the diet drugs Pondimin® (“Fenfluramine”) and/or Redux™ (“Dexfenfluramine”) and who has a condition that may qualify the patient, his or her legal representatives and/or members of the family for payment as part of the Nati ...
Left ventricular mass index measured by quantitative gated
Left ventricular mass index measured by quantitative gated

... measuring left ventricular mass in clinical practice, but it samples only a diastolic dimension measured by the Mmode of a long-axis view of the left ventricle and may be inaccurate in some myocardial infarction patients because of deformity of the cardiac chamber. Good-quality echocardiograhic reco ...
Disfungsi Diastolik Ventrikel Kiri pada Pasien Diabetes Melitus Tipe 2 :
Disfungsi Diastolik Ventrikel Kiri pada Pasien Diabetes Melitus Tipe 2 :

... Faculty of Medicine, University of Indonesia/Cipto-Mangunkusumo Hospital, Jakarta, since October 2003 until February 2004, were examined for echocardiography ( 2-D, M-mode, Doppler imaging ).Diastolic dysfunction was found in 58.1 % of chronic renal failure patients on hemodialysis. There was no sig ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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