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Early Increase in Left Ventricular Compliance after Myocardial
Early Increase in Left Ventricular Compliance after Myocardial

... myocardial infarction was first induced by the injection of 0.2 cc of elemental Hg into the left circumflex coronary artery via a small pericardial incision. Infarctions so produced resulted in gross absence of contraction over approximately 25% of the LV surface. Exactly 1 hr after infarction, thes ...
Case
Case

... while potassium level was still low. Furthermore, hypokalemia could also be the concomitant factor for QT prolongation. The cause of hypokalemia isn’t entirely clear; it most probably was attributed to the renal loss from chronic diuretic therapy. But the fact that potassium level decreased on hospi ...
Document
Document

... (d) Ventricular systole— second phase: As ventricular pressure rises and exceeds pressure in the arteries, the semilunar valves open and blood is ejected. ...
Robotics in Cardiac Surgery: Past, Present, and Future
Robotics in Cardiac Surgery: Past, Present, and Future

... dexterity and degrees of freedom, tremor-free movements, ambidexterity, and the avoidance of the fulcrum effect that is intrinsic when using long-shaft endoscopic instruments. Also, optics and operative visualization are vastly improved compared with direct vision and traditional videoscopes. Roboti ...
Vassalos, A. and Lilley, S. and Young, D. and Peng, E. and
Vassalos, A. and Lilley, S. and Young, D. and Peng, E. and

... which, in the context of congenital heart disease, is frequently characterised by pressure or volume loading w10x. From the preoperative data it was found that, not only were the patients with cardiac lesions observed to have reduced velocities compared to controls, the extent of velocity reduction ...
valve
valve

... • Lungs  pulmonary veins  left atrium • Left atrium  bicuspid valve  left ventricle • Left ventricle  aortic semilunar valve  aorta • Aorta  systemic circulation ...
Cardiac developmental toxicity
Cardiac developmental toxicity

... the resulting cardiac defect is the clearest way to establish CHD risk. Practical and ethical considerations, however, make this type of data difficult to collect. Only some states report CHD in a birth defects registry and reporting is usually only for obvious CHD cases with an adverse impact on he ...
Assessment of longitudinal left ventricular systolic function by
Assessment of longitudinal left ventricular systolic function by

... Doppler velocity (TDV) in newly diagnosed mild to moderate hypertensive patients. Methods: Our cross-sectional and observational study population consisted of 57 patients and 48 normotensive control subjects. Patients with obesity, diabetes mellitus, regional wall motion abnormality, secondary hyper ...
Ascending Aorta-Right Pulmonary Artery Shunt in
Ascending Aorta-Right Pulmonary Artery Shunt in

... with a variety of cyanotic cardiac abnormalities in which there is pulmonary stenosis or atresia. Seventy-one per cent of the infant group and 90% of patients over 1 year of age were long-term survivors (up to 6 years). Tetralogy of Fallot was the most commonly encountered anomaly in all 141 patient ...
Comparison of QT Dispersion With Left Ventricular Mass Index in
Comparison of QT Dispersion With Left Ventricular Mass Index in

... six months. Patients with clinical signs of CHF, arrhythmias, heart valve diseases, hypertension, obesity, metabolic, renal, or cardiac disorders, and the patients who needed complex cardiac treatments were excluded from the study. Patients were compared with 60 healthy individuals. Patients’ select ...
PDF - Circulation: Arrhythmia and Electrophysiology
PDF - Circulation: Arrhythmia and Electrophysiology

... in the overall ICAVB group was significantly worse than that of the age- and sex-specific Olmsted County, Minn, population rates. This difference was, however, attributable to the development of HF and ventricular dysfunction in those who had tested positive for antinuclear antibody (ANA) during adu ...
The advent of cardiac resynchronization therapy has created a
The advent of cardiac resynchronization therapy has created a

... the Internet (third party insurers, etc.) in relation to CRT [46–49]. This entity does not exist because HF by definition must have congestion and be symptomatic though the symptoms may sometimes be unimpressive. This mistake is similar to using “class I NYHA HF” to describe HF incorrectly in an asy ...
Prognostic value of T peak-to-end Interval for risk stratification after
Prognostic value of T peak-to-end Interval for risk stratification after

... Aim: Fatal Arrhythmia is the main cause of sudden death in patients with acute myocardial infarction either during hospital admission or in post-discharge period. Our aim is to identify groups at high risk of arrhythmic mortality by using a simple bed-side test in Electrocardiogram. Background: Tran ...
Risk Stratification for Sudden Cardiac Death after Acute Myocardial
Risk Stratification for Sudden Cardiac Death after Acute Myocardial

... ICD at the time of coronary artery bypass surgery or to a control group. The investigators found no significant difference in survival between the 2 groups during an average follow-up of 32 ± 16 months. One explanation for this negative finding is that patients recruited in this study (on the basis ...
3 Bipolar Limb Leads
3 Bipolar Limb Leads

... base of the heart to the apex. At the very end of depolarization the current reverses from 1/100 second and flows toward the outer walls of the ventricles near the base (S wave). ...
Stretch-induced modifications of myocardial performance: from
Stretch-induced modifications of myocardial performance: from

... skinned cardiac muscles in which all membranes had been removed and troponin C was directly accessible to calcium. They showed [61] that the change in affinity of troponin C for calcium was more closely correlated with the increase in tension than with the increase in length. The problem of whether ...
Relationship between plasma aldosterone and left ventricular
Relationship between plasma aldosterone and left ventricular

... We did not find a difference in PRA and aldosterone between normotensives and hypertensives. According to some authors, essential hypertension can be devided into three groups – low, normal and high renin essential hypertension. There were all three groups of patients in our study, so that the mean ...
Print - Circulation
Print - Circulation

... proven, by electrocardiographic recordings of spontaneous sustained monomorphic VT onset that demonstrate a morphology of the first premature beat differing from that of subsequent tachycardia beats.70 An unsustained initiating salvo of premature ventricular beats can be either monomorphic or polymo ...
Restriction and Constriction
Restriction and Constriction

... Restriction and Constriction Mitral inflow E wave is elevated in both Annular E wave  Restriction, peak E-wave < 8 cm/sec  Constriction, Peak E-wave > 8 cm/sec The above is Premised on the assumption that: Annular E wave is preload independent. Both Pro- and Con- studies regarding this premise exi ...
Chapter 7
Chapter 7

... In this most common congenital defect there is a hole in the septum that separates the right and left ventricles (Fig. 7.2). As a result, blood is short-circuited back into the lungs, putting a burden on both heart and lungs. About 30 percent to 50 percent of these holes, especially the smaller ones ...
16 Myocardial Disease
16 Myocardial Disease

... bundles in different orientations separated by connective tissue. This seminal case series highlighted four cardinal features of the disease: unexplained hypertrophy of the left ventricle, myocyte disarray, familial occurrence and an association with sudden cardiac death (SCD). The pathological desc ...
Fusion beat in patients with heart failure treated with left ventricular
Fusion beat in patients with heart failure treated with left ventricular

... haemodynamic improvement, even during physical exercise [17]. In patients with left ventricular conduction delay and sinus rhythm, LVP alone significantly increases LV systolic function. Although indications for LVP must still be clear defined, there is growing evidence suggesting that applying LVP ...
28 Ejection Clicks
28 Ejection Clicks

... being very responsive to changes in ventricular volume induced by posture or pharmacologic agents . Originally these nonejection clicks were thought to be extracardiac, but Barlow and subsequently others have clearly demonstrated their cardiac origin . Mitral and tricuspid clicks usually move to an ...
Approach to syncope
Approach to syncope

... pressure resulting in inadequate cardiac output leading to syncope. - d) Bradycardia - Examples of syncope in response to bradycardia include sinus node disease, and congenital and acquired heart block. The heart rate is found to be slower in patients with bradycardia and inadequate to maintain a op ...
Cardiac sympathetic activity in chronic heart failure: cardiac 123I
Cardiac sympathetic activity in chronic heart failure: cardiac 123I

... Cardiac sympathetic hyperactivity is reflected by a decreased 123I-mIBG late H/M ratio and increased WO. Both are associated with increased fatal arrhythmia and cardiac mortality. It has been reported that late H/M ratio < 1.6 is associated with poor outcome [29]. However, meta-analyses showed that ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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