Appendix 1 - BioMag Laboratory
... Seizures that have occurred with rTMS parameters outside 1998 safety guidelines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
... Seizures that have occurred with rTMS parameters outside 1998 safety guidelines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
(2006) Changes in visual receptive fields with microstimulation of
... stimulus and the endpoint of the evoked saccade was 0.8º and 7.1º for aligned and misaligned conditions, respectively. We quantified the relative responsiveness of each V4 neuron to aligned and misaligned stimuli and examined whether it was altered by subthreshold FEF stimulation. For each neuron, w ...
... stimulus and the endpoint of the evoked saccade was 0.8º and 7.1º for aligned and misaligned conditions, respectively. We quantified the relative responsiveness of each V4 neuron to aligned and misaligned stimuli and examined whether it was altered by subthreshold FEF stimulation. For each neuron, w ...
Slide 1
... • Possible detrimental effects of excessive loading damaging fragile new tissue and harming the healing response • Still no standard protocols for the amount, time, and advancement of weight bearing • Published studies use many different weight-bearing protocols • Main concern will be for poorly vas ...
... • Possible detrimental effects of excessive loading damaging fragile new tissue and harming the healing response • Still no standard protocols for the amount, time, and advancement of weight bearing • Published studies use many different weight-bearing protocols • Main concern will be for poorly vas ...
mGluR-dependent persistent firing in entorhinal cortex layer III neurons SYNAPTIC MECHANISMS Motoharu Yoshida,
... membrane was ruptured with negative pressure. Current-clamp recordings were made with a Multi Clamp 700B amplifier (Axon Instruments, Foster City, CA, USA). Signals were lowpass-filtered at 5 or 10 kHz and sampled at 10 or 20 kHz, respectively, using Clampex 9.0 software (Axon Instruments, Foster City ...
... membrane was ruptured with negative pressure. Current-clamp recordings were made with a Multi Clamp 700B amplifier (Axon Instruments, Foster City, CA, USA). Signals were lowpass-filtered at 5 or 10 kHz and sampled at 10 or 20 kHz, respectively, using Clampex 9.0 software (Axon Instruments, Foster City ...
Safety, ethical considerations, and application guidelines for the use
... Seizures that have occurred with rTMS parameters outside 1998 safety guidelines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
... Seizures that have occurred with rTMS parameters outside 1998 safety guidelines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
NIH eRA Commons user name: AM2518 TELEPHONE NUMBER
... the pre-SMA/ACC hyperactivation found in OCD, and eventually test whether by inhibiting this system through the pre-SMA OCD patients will show a clinical improvement. A handful of studies have used TMS to treat OCD by modulating activity in prefrontal circuits, with variable results. Greenberg et al ...
... the pre-SMA/ACC hyperactivation found in OCD, and eventually test whether by inhibiting this system through the pre-SMA OCD patients will show a clinical improvement. A handful of studies have used TMS to treat OCD by modulating activity in prefrontal circuits, with variable results. Greenberg et al ...
Heterogeneous Integration of Bilateral Whisker Signals by Neurons
... cortical column” by suppressing weaker responses so that “only . . . the initial perturbation of the principal whiskers will overcome the . . . cortical inhibition” (Brumberg et al. 1996). For Armstrong-James (1995), a “transient insularity” between barrels includes the whole cortical column centere ...
... cortical column” by suppressing weaker responses so that “only . . . the initial perturbation of the principal whiskers will overcome the . . . cortical inhibition” (Brumberg et al. 1996). For Armstrong-James (1995), a “transient insularity” between barrels includes the whole cortical column centere ...
PDF - Oxford Academic - Oxford University Press
... this inhibition are still largely unknown. Notably, whether such an inhibition of nociception occurs at the cortical level has not been investigated at all. Many previous studies have considered the dorsal horn of the spinal cord as an important site for this phenomenon where large myelinated fiber i ...
... this inhibition are still largely unknown. Notably, whether such an inhibition of nociception occurs at the cortical level has not been investigated at all. Many previous studies have considered the dorsal horn of the spinal cord as an important site for this phenomenon where large myelinated fiber i ...
Cortical remodelling induced by activity of ventral tegmental
... region (collectively called non-AI pairs; data not shown). In general, correlation strengths decreased as a regular function of cortical distance for both AI and non-AI pairs. VTA/tone-pairing did not change the correlation±distance function of AI pairs, but resulted in a strong increase in the corr ...
... region (collectively called non-AI pairs; data not shown). In general, correlation strengths decreased as a regular function of cortical distance for both AI and non-AI pairs. VTA/tone-pairing did not change the correlation±distance function of AI pairs, but resulted in a strong increase in the corr ...
Mechanisms of Magnetic Stimulation of Central Nervous System
... funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors have declared that no competing interests exist. ...
... funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors have declared that no competing interests exist. ...
Properties of Single Neurons Responsive to Light Mechanical
... stimulating device was constructed. It consisted of a perimeter of six electrolytically sharpened stainless steel electrodes surrounding a single central electrode. All electrodes were insulated to within 250 pm of the tip with epoxylite varnish. Adjacent perimetric electrodes had a 1 mm tip separat ...
... stimulating device was constructed. It consisted of a perimeter of six electrolytically sharpened stainless steel electrodes surrounding a single central electrode. All electrodes were insulated to within 250 pm of the tip with epoxylite varnish. Adjacent perimetric electrodes had a 1 mm tip separat ...
Column-Based Model of Electric Field Excitation of Cerebral Cortex
... very robust response in the M1-hand region for finger movement. The group-mean location of the finger-movement response was ⫺45, ⫺20, ⫹45 (x, y, z). Having made this initial determination of the group-mean location, a per-subject analysis was then carried out specifically targeting the M1hand region. P ...
... very robust response in the M1-hand region for finger movement. The group-mean location of the finger-movement response was ⫺45, ⫺20, ⫹45 (x, y, z). Having made this initial determination of the group-mean location, a per-subject analysis was then carried out specifically targeting the M1hand region. P ...
Aalborg Universitet Assessment of sensory convergence in the spinal cord
... anxiety, expectation etc. However, specific aspects of pain can be conceptualized (Loeser and Melzack, 1999). The difference between the concepts of nociception and the perception of pain must be appreciated. Nociception is in general thought of as the detection of actual or potential tissue damage ...
... anxiety, expectation etc. However, specific aspects of pain can be conceptualized (Loeser and Melzack, 1999). The difference between the concepts of nociception and the perception of pain must be appreciated. Nociception is in general thought of as the detection of actual or potential tissue damage ...
Identified Serotonergic Neurons LCBI and RCBI in the Cerebral
... We next addressed the question of whether stimulating the CBl cells in a manner similar to their response to tail shock produces reliable facilitation of the EPSP from LE sensory cells to follower cells. CBl neurons were identified as described above. An LE sensory cell and a follower neuron (usuall ...
... We next addressed the question of whether stimulating the CBl cells in a manner similar to their response to tail shock produces reliable facilitation of the EPSP from LE sensory cells to follower cells. CBl neurons were identified as described above. An LE sensory cell and a follower neuron (usuall ...
Lemniscal recurrent and transcortical influences on
... of CL neurons by intranuclear recurrent collateral branches of CL axons and via the lemniscal-thalamocortico-cuneate loop might constitute two linked synchronizing mechanisms. The CL fibers emit recurrent collaterals before entering the medial lemniscus (ML),10. and 22. and ML stimulation induces sy ...
... of CL neurons by intranuclear recurrent collateral branches of CL axons and via the lemniscal-thalamocortico-cuneate loop might constitute two linked synchronizing mechanisms. The CL fibers emit recurrent collaterals before entering the medial lemniscus (ML),10. and 22. and ML stimulation induces sy ...
Optogenetic drive of neocortical pyramidal neurons generates fMRI
... (FBOLD(1790)=6.56, P=0.01). The SUA responses demonstrated a pattern similar to the BOLD response, showing a gradual increase in firing rate and exhibiting an overall higher firing rate for Poisson relative to periodic stimulation (Fig. 4B; main effect of stimulation frequency FSUA(41,290)=4.12, P<0 ...
... (FBOLD(1790)=6.56, P=0.01). The SUA responses demonstrated a pattern similar to the BOLD response, showing a gradual increase in firing rate and exhibiting an overall higher firing rate for Poisson relative to periodic stimulation (Fig. 4B; main effect of stimulation frequency FSUA(41,290)=4.12, P<0 ...
file
... intensities to the contralateral ear at a rate of 2 stimuli per s. The evoked spikes of a neuron or a small cluster of 2–5 neurons were collected at each site. Primary auditory cortex was defined on the basis of the short latency (8–20 ms) of its evoked neuronal spike responses and its contin730 ...
... intensities to the contralateral ear at a rate of 2 stimuli per s. The evoked spikes of a neuron or a small cluster of 2–5 neurons were collected at each site. Primary auditory cortex was defined on the basis of the short latency (8–20 ms) of its evoked neuronal spike responses and its contin730 ...
Print this article - University of Toronto Journal of Undergraduate Life
... The treatment of Parkinson’s disease (PD) relies heavily on levodopa therapy. Although highly effective in ameliorating the debilitating symptoms of PD, levodopa treatment is largely associated with the development of abnormal involuntary movements. Several studies have suggested that these motor co ...
... The treatment of Parkinson’s disease (PD) relies heavily on levodopa therapy. Although highly effective in ameliorating the debilitating symptoms of PD, levodopa treatment is largely associated with the development of abnormal involuntary movements. Several studies have suggested that these motor co ...
Axonal conduction properties of antidromically identified neurons in
... In nine experiments, under halothane anesthesia, we identified the vibrissa representation in motor cortex using intracortical microstimulation through Teflon-coated stainless steel wires (diameter = 125 m m) insulated to within 0.5 mm of a beveled tip. Thirty-ms trains of 0.2 ms duration pulses wer ...
... In nine experiments, under halothane anesthesia, we identified the vibrissa representation in motor cortex using intracortical microstimulation through Teflon-coated stainless steel wires (diameter = 125 m m) insulated to within 0.5 mm of a beveled tip. Thirty-ms trains of 0.2 ms duration pulses wer ...
Deep Brain stimulation in the Treatment of Dystonia – The
... patients require optimization during post-‐operative care with varying evidence of optimal parameters. Unlike in Parkinson’s disease where there is often immediate impact, in dystonia improvement occurs ...
... patients require optimization during post-‐operative care with varying evidence of optimal parameters. Unlike in Parkinson’s disease where there is often immediate impact, in dystonia improvement occurs ...
Swallowing reflex and brain stem neurons activated by superior
... All the preparations were examined with a Zeiss Axioplan microscope. Images were captured on a Hamamatsu camera with Openlab software. c-fos-positive neurons per coronal sections that showed the maximum number of activated neurons were quantitated semiquantitatively and scored as follows: ⫺, for non ...
... All the preparations were examined with a Zeiss Axioplan microscope. Images were captured on a Hamamatsu camera with Openlab software. c-fos-positive neurons per coronal sections that showed the maximum number of activated neurons were quantitated semiquantitatively and scored as follows: ⫺, for non ...
Optical Control of Muscle Function by Transplantation of Stem Cell
... function. We generated murine embryonic stem cell–derived motor neurons that express the light-sensitive ion channel channelrhodopsin-2, which we then engrafted into partially denervated branches of the sciatic nerve of adult mice. These engrafted motor neurons not only reinnervated lower hind-limb ...
... function. We generated murine embryonic stem cell–derived motor neurons that express the light-sensitive ion channel channelrhodopsin-2, which we then engrafted into partially denervated branches of the sciatic nerve of adult mice. These engrafted motor neurons not only reinnervated lower hind-limb ...
Neurochemical excitation of propriospinal neurons facilitates
... NaHCO3, 1.0 MgSO4, and 30 glucose, equilibrated to pH 7.4 with 95% O2-5% CO2. The brain stem and spinal cord were then isolated ventral side up and bilaterally intact. Experiments were conducted at room temperature (ACSF ⬃22°C). Preparations were left in the bath solution, unstimulated, for ⬃1h befo ...
... NaHCO3, 1.0 MgSO4, and 30 glucose, equilibrated to pH 7.4 with 95% O2-5% CO2. The brain stem and spinal cord were then isolated ventral side up and bilaterally intact. Experiments were conducted at room temperature (ACSF ⬃22°C). Preparations were left in the bath solution, unstimulated, for ⬃1h befo ...
Fig. 2 - eNeuro
... suction electrode was placed on the head skin to induce the KO response. Natural tadpole swimming behavior was observed in a 5-cm dish with 1-mm grid paper underneath and videoed at 120 or 240 fps using a GoPro HERO4 silver camera. A current amplifier was used to drive a speaker, whose membrane was ...
... suction electrode was placed on the head skin to induce the KO response. Natural tadpole swimming behavior was observed in a 5-cm dish with 1-mm grid paper underneath and videoed at 120 or 240 fps using a GoPro HERO4 silver camera. A current amplifier was used to drive a speaker, whose membrane was ...
Stimulation-Induced Functional Decoupling (SIFD)
... Intuitively, electrical stimulation of neurons should increase spiking activity (assumed in Rubin and Terman, 2004) However: in vivo recordings in MPTP monkeys show a decrease in STN neurons activity! (Meissner et al., 2005) Furthermore: GPi cells (target of STN cells) are activated at high-frequenc ...
... Intuitively, electrical stimulation of neurons should increase spiking activity (assumed in Rubin and Terman, 2004) However: in vivo recordings in MPTP monkeys show a decrease in STN neurons activity! (Meissner et al., 2005) Furthermore: GPi cells (target of STN cells) are activated at high-frequenc ...