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... researchers have recorded and electrically stimulated cultured networks at multiple spatial locations (Gross et al., 1993b; Tateno and Jimbo, 1999; Shahaf and Marom, 2001). We developed a closed-loop paradigm (Potter et al., 1997; DeMarse et al., 2001; Potter et al., 2004) consisting of a sensory-mo ...
... researchers have recorded and electrically stimulated cultured networks at multiple spatial locations (Gross et al., 1993b; Tateno and Jimbo, 1999; Shahaf and Marom, 2001). We developed a closed-loop paradigm (Potter et al., 1997; DeMarse et al., 2001; Potter et al., 2004) consisting of a sensory-mo ...
Introduction
... Specific psychotherapy alone may be used as an initial treatment modality for patients with mild to moderate major depressive disorder (Practice Guideline for the Treatment of Patients with Major Depressive Disorder, 2000). The most studied form of psychotherapy used to treat MDD is Cognitive Behavi ...
... Specific psychotherapy alone may be used as an initial treatment modality for patients with mild to moderate major depressive disorder (Practice Guideline for the Treatment of Patients with Major Depressive Disorder, 2000). The most studied form of psychotherapy used to treat MDD is Cognitive Behavi ...
Integrative actions of the reticular formation The reticular activating
... and Bowden (1949) that basal diencephalic injury produced more profound EEG sleep changes than did the cerveau isol~ preparation, in which optic and olfactory pathways could still provide afferents to the R.F •• Forbes (1949) found it difficult to assume that barbiturate anesthesia, which synchroniz ...
... and Bowden (1949) that basal diencephalic injury produced more profound EEG sleep changes than did the cerveau isol~ preparation, in which optic and olfactory pathways could still provide afferents to the R.F •• Forbes (1949) found it difficult to assume that barbiturate anesthesia, which synchroniz ...
ppt - BIAC – Duke
... In this period of intense research in the neurosciences, nothing is more promising than functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) methods, which localize brain activities. These functional imaging methodologies map neurophysiological responses to cognitive, ...
... In this period of intense research in the neurosciences, nothing is more promising than functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) methods, which localize brain activities. These functional imaging methodologies map neurophysiological responses to cognitive, ...
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... humans (19) and has been found to be associated with auditory attention (1, 20, 41) resulting in top-down modulation of auditory processing (25). This finding was further confirmed by electrophysiological data indicating that tinnitus might occur as the result of a dysfunction in the top-down inhibito ...
... humans (19) and has been found to be associated with auditory attention (1, 20, 41) resulting in top-down modulation of auditory processing (25). This finding was further confirmed by electrophysiological data indicating that tinnitus might occur as the result of a dysfunction in the top-down inhibito ...
High vs. Low Electrical Stimulation Frequencies for Motor Recovery
... Studies that investigate the use of FES to restore hand function following stroke are few. Some investigators suggest that the inherent complexity of hand movements limit the amount of investigation in this area (Binder-Macleod & Lee, 1997). In some of the available research, subjects receiving ele ...
... Studies that investigate the use of FES to restore hand function following stroke are few. Some investigators suggest that the inherent complexity of hand movements limit the amount of investigation in this area (Binder-Macleod & Lee, 1997). In some of the available research, subjects receiving ele ...
Forebrain Origins and Terminations of the Medial Forebrain Bundle
... by more than 0.1 log unit from one determination to the next. Animals were assigned to groups in such a way as to approximately equate the currents used. Rats in the self-stimulating (SS) group were paired with rats in the PS group, so that current intensity did not differ by more than 20% within a ...
... by more than 0.1 log unit from one determination to the next. Animals were assigned to groups in such a way as to approximately equate the currents used. Rats in the self-stimulating (SS) group were paired with rats in the PS group, so that current intensity did not differ by more than 20% within a ...
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... relevance of these areas as targets for the treatment of depression. Previous studies already demonstrated that TMS with a figure-of-eight coil over the left dorsolateral prefrontal cortex (DLPFC) modulates the blood now in the ACC (Paus and Barrett, 2004). Activity in the ACC has also been identifi ...
... relevance of these areas as targets for the treatment of depression. Previous studies already demonstrated that TMS with a figure-of-eight coil over the left dorsolateral prefrontal cortex (DLPFC) modulates the blood now in the ACC (Paus and Barrett, 2004). Activity in the ACC has also been identifi ...
Repetitive Transcranial Magnetic Stimulation (rTMS) for the
... Background: Repetitive Transcranial Magnetic Stimulation (rTMS) has been proposed as a new tool in neurological rehabilitation of victims of traumatic brain injury (TBI). However, its usefulness to treat this condition has never been tested rigorously. The primary goal is to conduct a study protocol ...
... Background: Repetitive Transcranial Magnetic Stimulation (rTMS) has been proposed as a new tool in neurological rehabilitation of victims of traumatic brain injury (TBI). However, its usefulness to treat this condition has never been tested rigorously. The primary goal is to conduct a study protocol ...
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... between primary motor cortex and the adjacent premotor cortex is uncertain. A traditional view is that premotor cortex instructs primary motor cortex, which in turn instructs the spinal cord (Fulton, 1935). However, both premotor and primary motor cortex project directly to the spinal cord in comple ...
... between primary motor cortex and the adjacent premotor cortex is uncertain. A traditional view is that premotor cortex instructs primary motor cortex, which in turn instructs the spinal cord (Fulton, 1935). However, both premotor and primary motor cortex project directly to the spinal cord in comple ...
Long Term Effects of Low Frequency (10 Hz)
... left and right temporo-parietal electrodes (Fig. 1B). Beside these effects, the patient presented a significant clinical improvement, with a progressive decrease of the CDAI score and an endoscopic remission at month 12, associated to an increase of the parasympathetic tone as marked by the elevation ...
... left and right temporo-parietal electrodes (Fig. 1B). Beside these effects, the patient presented a significant clinical improvement, with a progressive decrease of the CDAI score and an endoscopic remission at month 12, associated to an increase of the parasympathetic tone as marked by the elevation ...
Repetitive transcranial magnetic stimulation for the treatment of
... Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive technique used to stimulate the human brain in vivo using very strong, pulsed magnetic fields. The technique involves the delivery of a magnetic pulse to the cortex of a subject through a hand-held stimulating coil applied directl ...
... Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive technique used to stimulate the human brain in vivo using very strong, pulsed magnetic fields. The technique involves the delivery of a magnetic pulse to the cortex of a subject through a hand-held stimulating coil applied directl ...
Locally evoked potentials in slices of the rat nucleus - UvA-DARE
... followed by a small positive component, P1 (Fig. 2A), N2 by a relatively long-lasting positive wave, P2. This field potential could be recorded in all subregions of the Acb, although P2 was most clearly seen in the region surr o u n d i n g the A C and in other border regions of the Acb. T h e posit ...
... followed by a small positive component, P1 (Fig. 2A), N2 by a relatively long-lasting positive wave, P2. This field potential could be recorded in all subregions of the Acb, although P2 was most clearly seen in the region surr o u n d i n g the A C and in other border regions of the Acb. T h e posit ...
Increased responses in trigeminocervical nociceptive neurons to cervical input after
... re¯ex and withdrawal re¯exes in the unparalysed state, and, during muscular paralysis, from the absence of gross ¯uctuations of blood pressure and heart rate. Arterial blood pressure was monitored continuously through the cannulated femoral artery. The animals were paralysed with pancuronium bromide ...
... re¯ex and withdrawal re¯exes in the unparalysed state, and, during muscular paralysis, from the absence of gross ¯uctuations of blood pressure and heart rate. Arterial blood pressure was monitored continuously through the cannulated femoral artery. The animals were paralysed with pancuronium bromide ...
Magnetic muscle stimulation produces fatigue without effort
... importance independent of systemic influences. To determine the fatigue properties of isolated muscles, the muscle is stimulated at a predetermined frequency, and the decline in force produced by a constant stimulus to the muscle is measured. To fatigue human muscles is often less straightforward. T ...
... importance independent of systemic influences. To determine the fatigue properties of isolated muscles, the muscle is stimulated at a predetermined frequency, and the decline in force produced by a constant stimulus to the muscle is measured. To fatigue human muscles is often less straightforward. T ...
Basal Ganglia Subcircuits Distinctively Encode the
... previously recorded during the behavioral performance. The stimulation train was either 25 pulses of 10 ms duration delivered at 5 Hz or 14 Hz, or 25 pulses of 1000 ms duration delivered at 0.5 Hz. Multiple stimulation trains were repeatedly used based on the condition of the animal and quality of c ...
... previously recorded during the behavioral performance. The stimulation train was either 25 pulses of 10 ms duration delivered at 5 Hz or 14 Hz, or 25 pulses of 1000 ms duration delivered at 0.5 Hz. Multiple stimulation trains were repeatedly used based on the condition of the animal and quality of c ...
Psychosurgery: past, present, and future
... the surgery fell to the hands of non-surgeons as well as nonphysicians. Electroconvulsive treatment (another controversial somatic therapy in psychiatry) was used for anesthesia, and then an instrument resembling an ice pick was inserted into the orbital roof and swept across the prefrontal cortex. ...
... the surgery fell to the hands of non-surgeons as well as nonphysicians. Electroconvulsive treatment (another controversial somatic therapy in psychiatry) was used for anesthesia, and then an instrument resembling an ice pick was inserted into the orbital roof and swept across the prefrontal cortex. ...
No Slide Title
... Muscle contraction mechanisms: recruitment : activation of an increasing number of motor units within a muscle on contraction ...
... Muscle contraction mechanisms: recruitment : activation of an increasing number of motor units within a muscle on contraction ...
Stimulation of GABAergic neurons of the lateral septum and its effect
... of the medial septum that project in the dorsal hippocampus through optogenetics. This stimulation, if done at theta frequencies (6 to 12Hz), caused theta oscillations which were measured through electrophysiological recordings from the hippocampus. Their interest in theta frequencies in the hippoca ...
... of the medial septum that project in the dorsal hippocampus through optogenetics. This stimulation, if done at theta frequencies (6 to 12Hz), caused theta oscillations which were measured through electrophysiological recordings from the hippocampus. Their interest in theta frequencies in the hippoca ...
Interactions Between the Lateral Hypothalamus and the
... recording was made from PAG neurons using a glass electrode (8-12 Ma) filled with 2 gm% pontamine skyblue dye in 0.5 M sodium acetate glued to another glass electode filled with 3 mM NT. Tungsten stimulating electrodes with tip diameters of 8-l 5 pm were placed in the LH and in the nucleus raphe mag ...
... recording was made from PAG neurons using a glass electrode (8-12 Ma) filled with 2 gm% pontamine skyblue dye in 0.5 M sodium acetate glued to another glass electode filled with 3 mM NT. Tungsten stimulating electrodes with tip diameters of 8-l 5 pm were placed in the LH and in the nucleus raphe mag ...
Occipital Nerve Stimulation Suppresses Nociception
... • ONS is an emerging therapy for chronic daily headache (e.g. chronic migraine) • Migraine pain may result from sensitization of the trigeminal nucleus caudalis • This study quantifies the effects of ONS on these neurons in a rat model of central trigeminal sensitization ...
... • ONS is an emerging therapy for chronic daily headache (e.g. chronic migraine) • Migraine pain may result from sensitization of the trigeminal nucleus caudalis • This study quantifies the effects of ONS on these neurons in a rat model of central trigeminal sensitization ...
A phase I trial of deep brain stimulation of memory
... assessment was the Alzheimer’s Disease Assessment Scale, Cognitive Subscale (ADAS-Cog).40 This was chosen due to its widespread use in clinical dementia trials as well as algorithms to predict rate of decline in AD patients as a function of baseline scores.41,42 It includes components assessing decl ...
... assessment was the Alzheimer’s Disease Assessment Scale, Cognitive Subscale (ADAS-Cog).40 This was chosen due to its widespread use in clinical dementia trials as well as algorithms to predict rate of decline in AD patients as a function of baseline scores.41,42 It includes components assessing decl ...
Properties of ventromedial hypothalamic neurons with axons
... (arrows) at an interval of 2.0 ms; (~) blockage of antidromic response by spontaneously generated spike (arrow head, T). Antidromic response to the second pulse ~ f t e r an interval of 5.0 ms) showed that the neuron was not lost; 4~)response to triggered stimuli with a delay larger than the critica ...
... (arrows) at an interval of 2.0 ms; (~) blockage of antidromic response by spontaneously generated spike (arrow head, T). Antidromic response to the second pulse ~ f t e r an interval of 5.0 ms) showed that the neuron was not lost; 4~)response to triggered stimuli with a delay larger than the critica ...
Transcranial Magnetic Stimulation: A Neuroscientific Probe of
... Additionally, spTMS or short trains of TMS during real-time EEG or other brain imaging methods can be used to activate a given cortical region and assess the distributed effects on the basis of transsynaptic corticocortical and corticosubcortical effects. Although this approach has yet to be applied ...
... Additionally, spTMS or short trains of TMS during real-time EEG or other brain imaging methods can be used to activate a given cortical region and assess the distributed effects on the basis of transsynaptic corticocortical and corticosubcortical effects. Although this approach has yet to be applied ...