Reaching for the brain: stimulating neural activity as the big leap in
... At the same time, the study also unveils some challenges that still stand in between the successful development of therapies for CNS restoration. Mirroring the time course of axonal regeneration, a therapy would have to induce neuroprotection followed by axonal sprouting, elongation and navigation, ...
... At the same time, the study also unveils some challenges that still stand in between the successful development of therapies for CNS restoration. Mirroring the time course of axonal regeneration, a therapy would have to induce neuroprotection followed by axonal sprouting, elongation and navigation, ...
Electrical stimulation of neural tissue to evoke behavioral responses
... estimate how far from the electrode tip current activates neural tissue mediating behaviors such as eating (Olds, 1958), self-stimulation (Wise, 1972; Fouriezos and Wise, 1984; Milner and Laferriere, 1986), and circling behavior (Yeomans et al., 1984, 1986). The method used by Fouriezos and Wise (19 ...
... estimate how far from the electrode tip current activates neural tissue mediating behaviors such as eating (Olds, 1958), self-stimulation (Wise, 1972; Fouriezos and Wise, 1984; Milner and Laferriere, 1986), and circling behavior (Yeomans et al., 1984, 1986). The method used by Fouriezos and Wise (19 ...
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... undiminished after hundreds of stimulation trials. (ii) Immediately after stimulating, we still could record from single neurons through the same electrode at the same location, the neurons showed no abnormalities in their spike trains, and the neurons were still responsive. (iii) On histology, the ...
... undiminished after hundreds of stimulation trials. (ii) Immediately after stimulating, we still could record from single neurons through the same electrode at the same location, the neurons showed no abnormalities in their spike trains, and the neurons were still responsive. (iii) On histology, the ...
TENS/5.
... erating circuit, Which generates a pulse Waveform having the desired parameters. One or more electrodes positioned ...
... erating circuit, Which generates a pulse Waveform having the desired parameters. One or more electrodes positioned ...
Poster Session Abstract Booklet - The New York Academy of Sciences
... high fidelity recordings, with a good number of extracted features in the principal component analysis (PCA) space. Another group of mice were implanted with the array and subjected to either electrical stimulation of the vagus nerve by delivering a 1 mA current (250 μs biphasic pulse, 50 μs interph ...
... high fidelity recordings, with a good number of extracted features in the principal component analysis (PCA) space. Another group of mice were implanted with the array and subjected to either electrical stimulation of the vagus nerve by delivering a 1 mA current (250 μs biphasic pulse, 50 μs interph ...
Activity-Dependent Regulation of Potassium Currents in an
... current level at time 0, i.e., immediately before the beginning of stimulation (downward arrow). Negative time indicates time before stimulation begins. Dashed lines indicate control values (i.e., 100%). Numbers of measurements are indicated in parentheses under the time axes below the time label; t ...
... current level at time 0, i.e., immediately before the beginning of stimulation (downward arrow). Negative time indicates time before stimulation begins. Dashed lines indicate control values (i.e., 100%). Numbers of measurements are indicated in parentheses under the time axes below the time label; t ...
Cerebellar Unit Activity and the Movement Disruption Induced by
... Sixteen male albino rats of the Wistar strain, about 3 months old, were reduced to 85 % of original body weight (200—250 g) and trained to reach for 20 mg pellets of Larsen's diet into a narrow (11 mm internal diameter) horizontal feeder attached to the front wall of a plexiglass chamber (Megirian e ...
... Sixteen male albino rats of the Wistar strain, about 3 months old, were reduced to 85 % of original body weight (200—250 g) and trained to reach for 20 mg pellets of Larsen's diet into a narrow (11 mm internal diameter) horizontal feeder attached to the front wall of a plexiglass chamber (Megirian e ...
Douglas B. Webster and Molly Webster
... a normally functioning peripheral structure under certain conditions. ...
... a normally functioning peripheral structure under certain conditions. ...
D22 - Viktor`s Notes for the Neurosurgery Resident
... facilitation) – more muscle fibers are responding. – postactivation facilitation is followed by longer-lasting period of depression, maximal between 2 and 4 min after conditioning exercise period and lasting for 10 min (postactivation exhaustion). miniature endplate potentials have subnormal ampli ...
... facilitation) – more muscle fibers are responding. – postactivation facilitation is followed by longer-lasting period of depression, maximal between 2 and 4 min after conditioning exercise period and lasting for 10 min (postactivation exhaustion). miniature endplate potentials have subnormal ampli ...
A multiple regression model of normal central and peripheral motor
... are 0.9 ms shorter than for electrical root stimulation, equivalent to a distance of about 4.5 cm if a nerve conduction velocity of 50 m/s is assumed.27 This suggests that the MATS coil excites spinal roots at a more distal point than standard coils, so that CMCT-M determined using MATS-based root l ...
... are 0.9 ms shorter than for electrical root stimulation, equivalent to a distance of about 4.5 cm if a nerve conduction velocity of 50 m/s is assumed.27 This suggests that the MATS coil excites spinal roots at a more distal point than standard coils, so that CMCT-M determined using MATS-based root l ...
Potential Utility of Optogenetics in the Study of
... underpinnings of depression-like behavior in animal depression models, as well as the antidepressant-like effects of DBS in these models. This approach has already been used to understand DBS action in Parkinson’s disease: optogenetic studies of rodent Parkinson’s models indicate that the therapeuti ...
... underpinnings of depression-like behavior in animal depression models, as well as the antidepressant-like effects of DBS in these models. This approach has already been used to understand DBS action in Parkinson’s disease: optogenetic studies of rodent Parkinson’s models indicate that the therapeuti ...
Cochlear Implant 1
... transforming acoustic pressure waves (sound) to neural impulses which in turn leads to hearing impairment. Hair cells damage might cause by diseases (e.g meningitis, Meniere’s). If large number of hair cells or auditory neurons throughout the cochlea are damaged, then the person with such a loss is ...
... transforming acoustic pressure waves (sound) to neural impulses which in turn leads to hearing impairment. Hair cells damage might cause by diseases (e.g meningitis, Meniere’s). If large number of hair cells or auditory neurons throughout the cochlea are damaged, then the person with such a loss is ...
Deep Brain Stimulation Does Not Silence Neurons in Subthalamic
... The functional lesion hypothesis received support from studies in humans and in a primate model of Parkinson’s disease in which high-frequency stimulation in the STN was seen to inhibit activity in surrounding cell bodies for periods of up to several seconds (Filali et al. 2004; Meissner et al. 2005 ...
... The functional lesion hypothesis received support from studies in humans and in a primate model of Parkinson’s disease in which high-frequency stimulation in the STN was seen to inhibit activity in surrounding cell bodies for periods of up to several seconds (Filali et al. 2004; Meissner et al. 2005 ...
Efficacy of repetitive transcranial magnetic stimulation (rTMS) in the
... fields of 1-10 mT are produced [5]. rTMS takes advantage of these laws of physics, composing a fluctuating magnetic field at a set frequency which induces an electrical current in brain tissue when positioned close to the scalp. The stimulation causes an electric activity in the brain cortex and dep ...
... fields of 1-10 mT are produced [5]. rTMS takes advantage of these laws of physics, composing a fluctuating magnetic field at a set frequency which induces an electrical current in brain tissue when positioned close to the scalp. The stimulation causes an electric activity in the brain cortex and dep ...
before ethics and morality
... What is ethical and moral behavior? What is moral education? Without a definition of the former, a curriculum for the latter cannot be developed. The diversity of ethical and moral behavior reflects the diversity of human societies. What is ethical and moral behavior for one may be unethical and imm ...
... What is ethical and moral behavior? What is moral education? Without a definition of the former, a curriculum for the latter cannot be developed. The diversity of ethical and moral behavior reflects the diversity of human societies. What is ethical and moral behavior for one may be unethical and imm ...
Erection - abuad lms
... tumescence(NPT). Absence of nocturnal erection is commonly used to distinguish between physical and psychological causes of erectile dysfunction and impotence. ...
... tumescence(NPT). Absence of nocturnal erection is commonly used to distinguish between physical and psychological causes of erectile dysfunction and impotence. ...
Shedding Light on the Role of Ventral Tegmental Area Dopamine in
... neurons to support instrumental responding in the absence of food reward using a procedure similar to electrical intracranial self-stimulation. In this paradigm, active-lever presses were followed only by optical stimulation of the VTA. ChR2 mice did not develop a preference for the active lever (Ad ...
... neurons to support instrumental responding in the absence of food reward using a procedure similar to electrical intracranial self-stimulation. In this paradigm, active-lever presses were followed only by optical stimulation of the VTA. ChR2 mice did not develop a preference for the active lever (Ad ...
Functional Specialization Within the Cat Red Nucleus
... electrical stimulation. Stimulus-triggered averaging has some practical advantages over spike-triggered averaging. One advantage is that the experimental demands are less because single units do not need to be isolated for a prolonged averaging period. A second advantage is that stimulation has a re ...
... electrical stimulation. Stimulus-triggered averaging has some practical advantages over spike-triggered averaging. One advantage is that the experimental demands are less because single units do not need to be isolated for a prolonged averaging period. A second advantage is that stimulation has a re ...
Principles of Electrical Currents
... causing a thermal effect. AC has a zero net charge (ZNC). The DC may have long term adverse physiological effects) ...
... causing a thermal effect. AC has a zero net charge (ZNC). The DC may have long term adverse physiological effects) ...
Deep transcranial magnetic stimulation add
... wrists, saying he wanted to be admitted to the hospital ...
... wrists, saying he wanted to be admitted to the hospital ...
English - SciELO México
... structures, such as amygdaloid complex and hippocampus. In the Wistar rat, 2-heptanone produces anxiety-like behavior and an increased firing rate of basal amygdaline neurons. However, it is unknown whether 2-heptanone modifies the responsivity of medial amygdalinehippocampal connection. Therefore, ...
... structures, such as amygdaloid complex and hippocampus. In the Wistar rat, 2-heptanone produces anxiety-like behavior and an increased firing rate of basal amygdaline neurons. However, it is unknown whether 2-heptanone modifies the responsivity of medial amygdalinehippocampal connection. Therefore, ...
An alarm pheromone increases the responsivity of
... structures, such as amygdaloid complex and hippocampus. In the Wistar rat, 2-heptanone produces anxiety-like behavior and an increased firing rate of basal amygdaline neurons. However, it is unknown whether 2-heptanone modifies the responsivity of medial amygdalinehippocampal connection. Therefore, ...
... structures, such as amygdaloid complex and hippocampus. In the Wistar rat, 2-heptanone produces anxiety-like behavior and an increased firing rate of basal amygdaline neurons. However, it is unknown whether 2-heptanone modifies the responsivity of medial amygdalinehippocampal connection. Therefore, ...
PREFERENTIAL POTENTIATION OF WEAKER INPUTS TO PRIMARY
... The ability of the brain to store information and adapt to changes in the sensory environment stem from the capability of neurons to change their communication with other neurons (“synaptic plasticity”). However, the ability of synapses to change (e.g., strengthen) is profoundly influenced by variou ...
... The ability of the brain to store information and adapt to changes in the sensory environment stem from the capability of neurons to change their communication with other neurons (“synaptic plasticity”). However, the ability of synapses to change (e.g., strengthen) is profoundly influenced by variou ...
Implantable microcoils for intracortical magnetic
... is required, it is well established that prolonged implantation into the cortex induces a foreign body response that can lead to the formation of a high-impedance glial sheath around the implant with a resultant increase in distance to targeted neurons (11, 12). Migration of neurons away from the im ...
... is required, it is well established that prolonged implantation into the cortex induces a foreign body response that can lead to the formation of a high-impedance glial sheath around the implant with a resultant increase in distance to targeted neurons (11, 12). Migration of neurons away from the im ...