Chapter 7 Body Systems
... several knobs being activated simultaneously and stimulating different locations on the postsynaptic membrane, producing an action potential ...
... several knobs being activated simultaneously and stimulating different locations on the postsynaptic membrane, producing an action potential ...
Discovery of a Proneurogenic, Neuroprotective
... the number of BrdU+ cells was normalized against the volume of the dentate gyrus. Because we considered both increased proliferation and survival of newborn neurons to be important screening parameters, we conducted our screen over 7 days in order to detect molecules that might augment either proces ...
... the number of BrdU+ cells was normalized against the volume of the dentate gyrus. Because we considered both increased proliferation and survival of newborn neurons to be important screening parameters, we conducted our screen over 7 days in order to detect molecules that might augment either proces ...
An implantable neural probe with monolithically integrated dielectric
... Similarly, silencing (hyperpolarizing) specific neurons within a region can provide information about their roles in both network functions and behavior. This goal cannot be achieved effectively by electrical stimulation since it indiscriminately stimulates neuronal processes, including somata, dend ...
... Similarly, silencing (hyperpolarizing) specific neurons within a region can provide information about their roles in both network functions and behavior. This goal cannot be achieved effectively by electrical stimulation since it indiscriminately stimulates neuronal processes, including somata, dend ...
Receptor Tyrosine Kinases: Molecular Switches Regulating CNS
... only a small number of axons show compensatory sprouting, resulting in poor functional recovery [1–5]. Lack or insufficient trophic support is one of the major determinants attributed to the failure of adult CNS axon regeneration. Growth factors that act both on neurons and glia, mediate a variety o ...
... only a small number of axons show compensatory sprouting, resulting in poor functional recovery [1–5]. Lack or insufficient trophic support is one of the major determinants attributed to the failure of adult CNS axon regeneration. Growth factors that act both on neurons and glia, mediate a variety o ...
View CV as a PDF - Cedars
... 1) Thomsen, G.M., Alkaslasi, M., Vit, J.P., Lawless, G., Godoy, M., Gowing, G., Shelest, O., Svendsen, C.N. Systemic injection of AAV9-GDNF provides modest functional improvements in the SOD1G93A ALS rat but has adverse associated side effects. Submitted, Gene Therapy. 2) Thomsen, G.M., Ma, A., Ko, ...
... 1) Thomsen, G.M., Alkaslasi, M., Vit, J.P., Lawless, G., Godoy, M., Gowing, G., Shelest, O., Svendsen, C.N. Systemic injection of AAV9-GDNF provides modest functional improvements in the SOD1G93A ALS rat but has adverse associated side effects. Submitted, Gene Therapy. 2) Thomsen, G.M., Ma, A., Ko, ...
Extracellular Matrix Molecules and Cell Adhesion Molecules Induce
... LN are used to coat nitrocellulose substrates (see also Fig. 2, E and F). The availability of purified CAMs that induce neurite growth allows a test of the generality of this C kinase result. H7 does not prevent the growth of neurites induced by Con A in CG neurons, suggesting that C kinase function ...
... LN are used to coat nitrocellulose substrates (see also Fig. 2, E and F). The availability of purified CAMs that induce neurite growth allows a test of the generality of this C kinase result. H7 does not prevent the growth of neurites induced by Con A in CG neurons, suggesting that C kinase function ...
Neural analysis of sound frequency in insects
... anatomical organization of the receptor neuron terminals in the central nervous system and on circuitry among interneurons. As in most sensory systems, the central target regions of receptor neurons are related to their positions at the periphery. Auditory receptors form a tonotopic ‘‘map’’ in the c ...
... anatomical organization of the receptor neuron terminals in the central nervous system and on circuitry among interneurons. As in most sensory systems, the central target regions of receptor neurons are related to their positions at the periphery. Auditory receptors form a tonotopic ‘‘map’’ in the c ...
A Feedback Model of Visual Attention
... This theory proposes that visual stimuli compete to be represented by cortical activity. Competition may occur at each stage along the visual information processing pathway. The outcome of the competition is influenced not only by bottom-up, sensory driven, processes but also by top-down, attention- ...
... This theory proposes that visual stimuli compete to be represented by cortical activity. Competition may occur at each stage along the visual information processing pathway. The outcome of the competition is influenced not only by bottom-up, sensory driven, processes but also by top-down, attention- ...
Response Characteristics of Spinal Cord Dorsal Horn Neurons in
... Hao, Jing-Xia, Ron C. Kupers, and Xiao-Jun Xu. Response characteristics of spinal cord dorsal horn neurons in chronic allodynic rats after spinal cord injury. J Neurophysiol 92: 1391–1399, 2004; 10.1152/jn.00121.2004. The physiological mechanisms of chronic pain in patients with spinal cord injury ( ...
... Hao, Jing-Xia, Ron C. Kupers, and Xiao-Jun Xu. Response characteristics of spinal cord dorsal horn neurons in chronic allodynic rats after spinal cord injury. J Neurophysiol 92: 1391–1399, 2004; 10.1152/jn.00121.2004. The physiological mechanisms of chronic pain in patients with spinal cord injury ( ...
Monkey Models of Recovery of Voluntary Hand
... rootlet (0.2 to 0.3 mm in diameter), and extracellular recordings are made of the discharge of one to a few axons at variable depths and locations in each fascicle (for further details see C. Darian-Smith 2004; C. Darian-Smith and Brown 2000; Darian-Smith and Darian-Smith 2004). Cutaneous receptive ...
... rootlet (0.2 to 0.3 mm in diameter), and extracellular recordings are made of the discharge of one to a few axons at variable depths and locations in each fascicle (for further details see C. Darian-Smith 2004; C. Darian-Smith and Brown 2000; Darian-Smith and Darian-Smith 2004). Cutaneous receptive ...
An Integrate-and-fire Model of Prefrontal Cortex Neuronal Activity during Performance of Goal-directed
... We propose that goal directed behavior is learned by associating states and actions that are separately represented by the population of neurons of individual minicolumns. A state is indicated by the perception of specific sensory stimuli or the perception of reward received, while an action is indic ...
... We propose that goal directed behavior is learned by associating states and actions that are separately represented by the population of neurons of individual minicolumns. A state is indicated by the perception of specific sensory stimuli or the perception of reward received, while an action is indic ...
A Cholinergic Mechanism for Reward Timing within Primary Visual Cortex Please share
... NIH Public Access Author Manuscript Neuron. Author manuscript; available in PMC 2014 February 20. ...
... NIH Public Access Author Manuscript Neuron. Author manuscript; available in PMC 2014 February 20. ...
Electrical Synapses in the Thalamic Reticular Nucleus
... the TRN. The intrinsic firing properties of TRN cells in both mice and rats were similar to previous descriptions (Steriade et al., 1997). The input resistance of the TRN neurons in rats was 166 ⫾ 54 M⍀ (all reported data are means ⫾ SD), and the time constant was 13.1 ⫾ 3.7 msec (n ⫽ 45). The prope ...
... the TRN. The intrinsic firing properties of TRN cells in both mice and rats were similar to previous descriptions (Steriade et al., 1997). The input resistance of the TRN neurons in rats was 166 ⫾ 54 M⍀ (all reported data are means ⫾ SD), and the time constant was 13.1 ⫾ 3.7 msec (n ⫽ 45). The prope ...
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... • Nervous systems process information in three stages: sensory input, integration, and motor output ...
... • Nervous systems process information in three stages: sensory input, integration, and motor output ...
- Stem-cell and Brain Research Institute
... generate a succession of distinct patterns of activation during the processing of an input sequence. The resulting pattern at the end of the presentation of a sequence thus characterizes the sequence and can be used to discriminate between sequences from different temporal structure categories. ...
... generate a succession of distinct patterns of activation during the processing of an input sequence. The resulting pattern at the end of the presentation of a sequence thus characterizes the sequence and can be used to discriminate between sequences from different temporal structure categories. ...
ARCHITECTONICS AND STRUCTURE OF THE CEREBRAL CORTEX
... words, although many pages are devoted to embryological and phylogenetic establishment of the six-layer diagram; but Brodmann's concept has proved to be based on faulty evidence.Sls At the foetal stages at which Brodmann reported the absence of stratification, the cortex, when properly stained by th ...
... words, although many pages are devoted to embryological and phylogenetic establishment of the six-layer diagram; but Brodmann's concept has proved to be based on faulty evidence.Sls At the foetal stages at which Brodmann reported the absence of stratification, the cortex, when properly stained by th ...
Gee JNeuro 2012 - Stanford University
... CT and CC neurons, respectively). In fact, the distributions of h-current from CT and CC neurons were completely nonoverlapping (Fig. 1C). Thus, we could define a threshold level of h-current that would unambiguously separate CT and CC neurons. We refer to layer V pyramidal neurons above this thresh ...
... CT and CC neurons, respectively). In fact, the distributions of h-current from CT and CC neurons were completely nonoverlapping (Fig. 1C). Thus, we could define a threshold level of h-current that would unambiguously separate CT and CC neurons. We refer to layer V pyramidal neurons above this thresh ...
Cranial Nerves
... muscle of the eye, which also controls the movement of the eye. These axons convey nerve impulses for proprioception. Cranial Nerve V is the trigeminal nerve, and likes its name has 3 branches, ophthalmic, maxillary, and mandibular. This cranial nerve conveys impulses for touch, pain, and temperatur ...
... muscle of the eye, which also controls the movement of the eye. These axons convey nerve impulses for proprioception. Cranial Nerve V is the trigeminal nerve, and likes its name has 3 branches, ophthalmic, maxillary, and mandibular. This cranial nerve conveys impulses for touch, pain, and temperatur ...
Ch 48 Nervous System
... • A thick band of axons, the corpus callosum – Provides communication between the right and ...
... • A thick band of axons, the corpus callosum – Provides communication between the right and ...
A Review of Cell Assemblies by Huyck and
... In a more complex form, two groups of cells can code for specific features, say lines of two given angles; activation of varying numbers or varying degrees of each set can represent an intermediate feature (Hubel and Wiesel, 1962). The degree of overlap is a topological issue (see Section 3.2) that ...
... In a more complex form, two groups of cells can code for specific features, say lines of two given angles; activation of varying numbers or varying degrees of each set can represent an intermediate feature (Hubel and Wiesel, 1962). The degree of overlap is a topological issue (see Section 3.2) that ...
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... Neocortical pyramidal neurons have a spike initiation zone in the apical dendrite [10,11,12,14,19]. The dendritic spike generated in this location is composed of an initial fast component that has been shown to be mediated by voltage-sensitive Na+ channels followed by a slower Ca2+-dependent compone ...
... Neocortical pyramidal neurons have a spike initiation zone in the apical dendrite [10,11,12,14,19]. The dendritic spike generated in this location is composed of an initial fast component that has been shown to be mediated by voltage-sensitive Na+ channels followed by a slower Ca2+-dependent compone ...
Lemniscal recurrent and transcortical influences on
... applied to the ML should induce a double discharge in the DCN, the first being produced through recurrent collaterals of activated lemniscal axons and the second by the activation of the thalamo-corticoDCN loop. This would imply that the corticofugal discharges excite lemniscal neurons,1., 15., 24., ...
... applied to the ML should induce a double discharge in the DCN, the first being produced through recurrent collaterals of activated lemniscal axons and the second by the activation of the thalamo-corticoDCN loop. This would imply that the corticofugal discharges excite lemniscal neurons,1., 15., 24., ...
Full Text
... they show activated Nodal/Activin, FGF and WNT pathways and have the potential for long-term maintenance in undifferentiated state and generation of three germ layer derivatives (Sato et al., 2004, Thomson et al., 1998, Xiao et al., 2006). Similar to LIF in mESCs, Activin A is sufficient and necessa ...
... they show activated Nodal/Activin, FGF and WNT pathways and have the potential for long-term maintenance in undifferentiated state and generation of three germ layer derivatives (Sato et al., 2004, Thomson et al., 1998, Xiao et al., 2006). Similar to LIF in mESCs, Activin A is sufficient and necessa ...
Nervous System Anatomy: Spinal Cord
... & other muscles of the lower leg & foot Formed from branches of the Tibial & Common Peroneal nn. Innervates skin of lower leg & foot ...
... & other muscles of the lower leg & foot Formed from branches of the Tibial & Common Peroneal nn. Innervates skin of lower leg & foot ...