Strain in Protein Structures as Viewed Through Nonrotameric Side
... larger protein structure set and observed that a significant fraction (up to 30%) of particular side-chain types could not be assigned to a rotameric state based on the criterion that rotameric side chains can deviate in each of the 1 and 2 angles by no more than 20° from the closest associated ro ...
... larger protein structure set and observed that a significant fraction (up to 30%) of particular side-chain types could not be assigned to a rotameric state based on the criterion that rotameric side chains can deviate in each of the 1 and 2 angles by no more than 20° from the closest associated ro ...
doc PHGY311
... concerning the daily cycle of light and darkness to body physiology and participates in the organization of circadian rhythms. Other signals perceived by the hypothalamus are visceral afferents that provide information to the central nervous system from peripheral ...
... concerning the daily cycle of light and darkness to body physiology and participates in the organization of circadian rhythms. Other signals perceived by the hypothalamus are visceral afferents that provide information to the central nervous system from peripheral ...
A Symmetric Approach Elucidates Multisensory Information Integration
... cortex, collects the highly-processed inputs conveyed by other associative areas. In this classical view, the sequential processing of information is hierarchical, such that the initial, low-level inputs are transformed into representations and multisensory integration emerges at multiple processing ...
... cortex, collects the highly-processed inputs conveyed by other associative areas. In this classical view, the sequential processing of information is hierarchical, such that the initial, low-level inputs are transformed into representations and multisensory integration emerges at multiple processing ...
How is Epilepsy Diagnosed?
... The brain consists of more than 100 billion nerve cells. These all communicate with one another; some provoke others into sending further messages (excitation), while others tend to block them (inhibition). The proper working of the brain depends on a balance between these: too many nerve cells send ...
... The brain consists of more than 100 billion nerve cells. These all communicate with one another; some provoke others into sending further messages (excitation), while others tend to block them (inhibition). The proper working of the brain depends on a balance between these: too many nerve cells send ...
NMDA receptor blockade causes selective prefrontal
... indicating that the overall effects of NMDAR-blockade may be better represented in regionally-specific intrinsic coupling changes (excitatory, or inhibitory), that affect specific sub-populations rather than extrinsic coupling between regions (56). ERP abnormalities – induced by NMDAR-blockade with ...
... indicating that the overall effects of NMDAR-blockade may be better represented in regionally-specific intrinsic coupling changes (excitatory, or inhibitory), that affect specific sub-populations rather than extrinsic coupling between regions (56). ERP abnormalities – induced by NMDAR-blockade with ...
Cognitive neuroscience of self-regulation failure
... inhibit craving, they show increased activity in regions of the prefrontal cortex (PFC) associated with self-control and reduced cue-reactivity in regions associated with reward processing. Specifically, Volkow and colleagues showed that when cocaine users inhibit their craving in response to cocain ...
... inhibit craving, they show increased activity in regions of the prefrontal cortex (PFC) associated with self-control and reduced cue-reactivity in regions associated with reward processing. Specifically, Volkow and colleagues showed that when cocaine users inhibit their craving in response to cocain ...
Effects of Cannabidiol (CBD) on Regional Cerebral Blood Flow
... applied to assess subjective states. In the second session, the same procedure was performed using the drug that had not been administered in the previous session. Within-subject between-condition rCBF comparisons were performed using statistical parametric mapping (SPM). CBD significantly decreased ...
... applied to assess subjective states. In the second session, the same procedure was performed using the drug that had not been administered in the previous session. Within-subject between-condition rCBF comparisons were performed using statistical parametric mapping (SPM). CBD significantly decreased ...
The role of the Golgi apparatus in neuronal polarity
... of the organelle and its role in protein trafficking. It is a dynamic organelle that receives vesicles containing proteins from the endoplasmic reticulum. As these vesicles traverse through the Golgi, resident proteins add post-translational modifications. The proteins are then trafficked to their d ...
... of the organelle and its role in protein trafficking. It is a dynamic organelle that receives vesicles containing proteins from the endoplasmic reticulum. As these vesicles traverse through the Golgi, resident proteins add post-translational modifications. The proteins are then trafficked to their d ...
What is Nervous System Fatigue and How do I Prevent it
... Nervous system fatigue can be grouped into 2 categories, peripheral and central. Central nervous system (CNS) fatigue is neural fatigue originating in the brain, brain stem, spinal cord, or spinal nerves. The exact mechanism for CNS fatigue remains largely unknown but it appears that acute CNS fatig ...
... Nervous system fatigue can be grouped into 2 categories, peripheral and central. Central nervous system (CNS) fatigue is neural fatigue originating in the brain, brain stem, spinal cord, or spinal nerves. The exact mechanism for CNS fatigue remains largely unknown but it appears that acute CNS fatig ...
PDF
... and layer 1, reveal that what appear to be columns in cross section have a variety of shapes and sizes. Ocular dominance columns, one of the textbook examples of columnar organization, are actually slab-like domains; and column width is variable as a function of the visual field; that is, larger in ...
... and layer 1, reveal that what appear to be columns in cross section have a variety of shapes and sizes. Ocular dominance columns, one of the textbook examples of columnar organization, are actually slab-like domains; and column width is variable as a function of the visual field; that is, larger in ...
Morphology, Deep cerebellar nuclei, C. gambianus
... With functional magnetic resonance imaging, the fastigial nucleus (FN) and globose / emboliform are seen to be thin and located close to the gray matter of lobules VIII and IX of the cerebellar cranial lobe [11]. The globose and emboliform nuclei in mammals are collectively referred to as nucleus in ...
... With functional magnetic resonance imaging, the fastigial nucleus (FN) and globose / emboliform are seen to be thin and located close to the gray matter of lobules VIII and IX of the cerebellar cranial lobe [11]. The globose and emboliform nuclei in mammals are collectively referred to as nucleus in ...
Neuronal Interaction Dynamics in Cat Primary Visual Cortex
... temperature, and EEG were monitored during the entire experiment. Respiration was adjusted for an end-tidal C O2 between 3.5 and 4.0%. The body temperature was kept at 37.5°C by means of a feedbackcontrolled heating pad. Contact lenses with artificial pupils (3 mm diameter) were used to cover the ey ...
... temperature, and EEG were monitored during the entire experiment. Respiration was adjusted for an end-tidal C O2 between 3.5 and 4.0%. The body temperature was kept at 37.5°C by means of a feedbackcontrolled heating pad. Contact lenses with artificial pupils (3 mm diameter) were used to cover the ey ...
Figure 1 - Journal of Neuroscience
... functions had broad spectral tuning (approximately three octaves) and were excitatory in the contralateral ear, inhibitory in the ipsilateral ear, and biased toward high frequencies. Responses to interaural time differences and spectral cues were relatively weak. In crossvalidation tests, the first- ...
... functions had broad spectral tuning (approximately three octaves) and were excitatory in the contralateral ear, inhibitory in the ipsilateral ear, and biased toward high frequencies. Responses to interaural time differences and spectral cues were relatively weak. In crossvalidation tests, the first- ...
Memantine is a clinically well tolerated N-methyl-D
... achieved in the treatment of dementia and is essentially devoid of such side effects at doses within the therapeutic range. This has been attributed to memantine’s moderate potency and associated rapid, strongly voltage-dependent blocking kinetics. The aim of this review is to summarise preclinical ...
... achieved in the treatment of dementia and is essentially devoid of such side effects at doses within the therapeutic range. This has been attributed to memantine’s moderate potency and associated rapid, strongly voltage-dependent blocking kinetics. The aim of this review is to summarise preclinical ...
Sensitization of the Trigeminal Sensory System During Different
... Objectives.—To determine if the sensitization of the trigeminal system changes after dural activation of the trigeminal nerve during different stages of the rat estrous cycle. Background.—The specific mechanisms through which ovarian hormones trigger menstrual migraine are currently unknown. Past an ...
... Objectives.—To determine if the sensitization of the trigeminal system changes after dural activation of the trigeminal nerve during different stages of the rat estrous cycle. Background.—The specific mechanisms through which ovarian hormones trigger menstrual migraine are currently unknown. Past an ...
Chapter 2 An Integrative Approach to Psychopathology
... The Interaction of Genetic and Environmental Effects Eric Kandel and Gene-Environment Interactions The Diathesis-Stress Model Examples include blood-injury-injection phobia and alcoholism Reciprocal Gene-Environment Model Examples include depression, divorce, and impulsivity Non-Genomic ...
... The Interaction of Genetic and Environmental Effects Eric Kandel and Gene-Environment Interactions The Diathesis-Stress Model Examples include blood-injury-injection phobia and alcoholism Reciprocal Gene-Environment Model Examples include depression, divorce, and impulsivity Non-Genomic ...
On the computational architecture of the neocortex
... and the remaining neurons all project directly to the cortex with no collaterals (with one exception: see discussion of R E thalamus below). Thus, except for the R E nucleus, the nuclei in the thalamus are not directly connected to each other. Where does the thalamus get its input? Some nuclei in th ...
... and the remaining neurons all project directly to the cortex with no collaterals (with one exception: see discussion of R E thalamus below). Thus, except for the R E nucleus, the nuclei in the thalamus are not directly connected to each other. Where does the thalamus get its input? Some nuclei in th ...
doc - UCA
... Treatment of an area of pain (joint OR soft tissue) with IFC. Requires quadpolar application (2 channels, surrounding the pain; “X marks the spot”; channel 1 & 2 oriented at 90 degree angles to each other as best you can on a 3D area of tissue or joint) o Acute Pain: use High Beat Freq (> 50Hz) , do ...
... Treatment of an area of pain (joint OR soft tissue) with IFC. Requires quadpolar application (2 channels, surrounding the pain; “X marks the spot”; channel 1 & 2 oriented at 90 degree angles to each other as best you can on a 3D area of tissue or joint) o Acute Pain: use High Beat Freq (> 50Hz) , do ...
Preparation for action: one of the key functions of motor cortex.
... information intervenes during processes of movement preparation or planning, but not during those of movement execution. The use of the preparatory paradigm makes it thus possible, first, to dissociate in time movement planning from its execution and, second, to study selectively preparatory process ...
... information intervenes during processes of movement preparation or planning, but not during those of movement execution. The use of the preparatory paradigm makes it thus possible, first, to dissociate in time movement planning from its execution and, second, to study selectively preparatory process ...
Temporal Patterning of Neural Progenitors in Drosophila
... but instead to close the preceding Krþ temporal identity window (Tran & Doe, 2008). The first four GMCs of NB3-1 lineage produce HB9þ,Isletþ RP motor neurons with a birth order of RP1 ! RP4 ! RP3 ! RP5 (and their non-RP siblings): Hb specifies RP1 and RP4 (high Hb: RP1; low Hb: RP4); Kr specifies RP ...
... but instead to close the preceding Krþ temporal identity window (Tran & Doe, 2008). The first four GMCs of NB3-1 lineage produce HB9þ,Isletþ RP motor neurons with a birth order of RP1 ! RP4 ! RP3 ! RP5 (and their non-RP siblings): Hb specifies RP1 and RP4 (high Hb: RP1; low Hb: RP4); Kr specifies RP ...
Networks of Spiking Neurons: The Third Generation of
... v. In the context of learning one can replace Wu,v by a function Wu,v(t). In addition it has been conjectured that rapid changes of the value of w~,~(t) are also essential for computations in biological neural systems. However for simplicity we view here Wu,v just as a constant. The restriction of W ...
... v. In the context of learning one can replace Wu,v by a function Wu,v(t). In addition it has been conjectured that rapid changes of the value of w~,~(t) are also essential for computations in biological neural systems. However for simplicity we view here Wu,v just as a constant. The restriction of W ...
Electrotherapeutics –Interferential Current
... Treatment of an area of pain (joint OR soft tissue) with IFC. Requires quadpolar application (2 channels, surrounding the pain; “X marks the spot”; channel 1 & 2 oriented at 90 degree angles to each other as best you can on a 3D area of tissue or joint) o Acute Pain: use High Beat Freq (> 50Hz) , do ...
... Treatment of an area of pain (joint OR soft tissue) with IFC. Requires quadpolar application (2 channels, surrounding the pain; “X marks the spot”; channel 1 & 2 oriented at 90 degree angles to each other as best you can on a 3D area of tissue or joint) o Acute Pain: use High Beat Freq (> 50Hz) , do ...
Branched thalamic afferents - the Sherman Lab
... The implied value of an efference copy is that it provides information of body movements, information needed to distinguish actual changes in the environment from those that are self-induced. One advantage of efference copy over proprioceptive feedback of bodily movements is that its signal is earli ...
... The implied value of an efference copy is that it provides information of body movements, information needed to distinguish actual changes in the environment from those that are self-induced. One advantage of efference copy over proprioceptive feedback of bodily movements is that its signal is earli ...
On the computational architecture of the neocortex
... and the remaining neurons all project directly to the cortex with no collaterals (with one exception: see discussion of R E thalamus below). Thus, except for the R E nucleus, the nuclei in the thalamus are not directly connected to each other. Where does the thalamus get its input? Some nuclei in th ...
... and the remaining neurons all project directly to the cortex with no collaterals (with one exception: see discussion of R E thalamus below). Thus, except for the R E nucleus, the nuclei in the thalamus are not directly connected to each other. Where does the thalamus get its input? Some nuclei in th ...
Clinical neurochemistry
Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.