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The postsynaptic NMDA-receptor–PSD-95
The postsynaptic NMDA-receptor–PSD-95

... the PSD and functions as a glutamategated calcium-permeable ion channel. NMDARs are anchored in the PSD by interactions between the cytoplasmic Cterminal tails of their NR2 subunits and the PDZ domains (orange) of PSD-95, an abundant PSD protein that forms a two-dimensional lattice immediately under ...
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... and in turn the small GTP-binding protein, RAS. Recruitment of RAF-1 to the plasma membrane by RAS leads to its activation triggering the MAPK cascade and cell proliferation. Binding of an ...
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Clinical neurochemistry



Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.
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