![Primitive Roles for Inhibitory Interneurons in Developing Frog Spinal](http://s1.studyres.com/store/data/016693950_1-b1bc72639efe0d4a8003d95740fd479e-300x300.png)
Primitive Roles for Inhibitory Interneurons in Developing Frog Spinal
... (Roberts, 2000; Li et al., 2001). These are shown diagrammatically in Figure 1, where their functions are listed. We have recently established that one class of spinal interneuron with a very characteristic axonal projection pattern, called ascending interneurons (aINs), produces phasic, glycinergic ...
... (Roberts, 2000; Li et al., 2001). These are shown diagrammatically in Figure 1, where their functions are listed. We have recently established that one class of spinal interneuron with a very characteristic axonal projection pattern, called ascending interneurons (aINs), produces phasic, glycinergic ...
Separate Representations of Target and Timing Cue Locations in
... the occurrence of each of these events was therefore predictable. In the memory-guided saccade task, in contrast, these events followed variable intervals ( fixation, 1,000 –1,300 ms; memory, 700 – 1,000 ms) and the occurrence of these events was thus not predictable. The timing-cue and target locat ...
... the occurrence of each of these events was therefore predictable. In the memory-guided saccade task, in contrast, these events followed variable intervals ( fixation, 1,000 –1,300 ms; memory, 700 – 1,000 ms) and the occurrence of these events was thus not predictable. The timing-cue and target locat ...
projecting to oculomotor regions of the pons Activity of monkey
... are true saccades (Robinson and Fuchs 1969). Neurons in the frontal eye field discharge before purposive saccades, even those made in the absence of visual stimuli (Bruce and Goldberg 1985). Monkeys with lesions of the frontal eye field are at first unable to make saccades into the field contralater ...
... are true saccades (Robinson and Fuchs 1969). Neurons in the frontal eye field discharge before purposive saccades, even those made in the absence of visual stimuli (Bruce and Goldberg 1985). Monkeys with lesions of the frontal eye field are at first unable to make saccades into the field contralater ...
Cortical connections of the visuomotor parietooccipital
... action potentials was 1 kHz and that for eye position 100 Hz. Standard visual stimuli (different in form, color, size, orientation, and direction and speed of movement) were used for testing the visual responsiveness of cells in record and for mapping their visual receptive fields. At the end of reco ...
... action potentials was 1 kHz and that for eye position 100 Hz. Standard visual stimuli (different in form, color, size, orientation, and direction and speed of movement) were used for testing the visual responsiveness of cells in record and for mapping their visual receptive fields. At the end of reco ...
Plasticity of Binocularity and Visual Acuity Are Differentially Limited
... mild but reproducible deficit in motor coordination on the rotarod (Kim et al., 2004; Lee et al., 2004). However, this motor coordination phenotype does not appear to affect their performance in the visual water task, as both the constitutive NgR1 mutant and conditional NgR1 mutants display performa ...
... mild but reproducible deficit in motor coordination on the rotarod (Kim et al., 2004; Lee et al., 2004). However, this motor coordination phenotype does not appear to affect their performance in the visual water task, as both the constitutive NgR1 mutant and conditional NgR1 mutants display performa ...
Hedonic Hotspots Regulate Cingulate-driven
... Positive hedonic states are known to attenuate the impact of demanding events on our body and brain, supporting adaptive behavior in response to changes in the environment. We used functional magnetic resonance imaging to examine the neural mechanism of this hedonic regulation. The effect of hedonic ...
... Positive hedonic states are known to attenuate the impact of demanding events on our body and brain, supporting adaptive behavior in response to changes in the environment. We used functional magnetic resonance imaging to examine the neural mechanism of this hedonic regulation. The effect of hedonic ...
Changes in the N1-P2 Complex after Speech
... 3, subjects participated in a fading task designed to emphasize the temporal cue (VOT) to be trained. Fading techniques are often used in training studies because they facilitate learning by providing a reference for listeners (Jamieson & Morosan, 1989). In a fading task, subjects are first presente ...
... 3, subjects participated in a fading task designed to emphasize the temporal cue (VOT) to be trained. Fading techniques are often used in training studies because they facilitate learning by providing a reference for listeners (Jamieson & Morosan, 1989). In a fading task, subjects are first presente ...
Acetaminophen Metabolism in Man, as Determined by High
... through dialysistubing (Union Carbide Corp., Food Products Division) with an air overpressure of 104 kPa (15 psig).The ultrafiltered serum samples were stored at -60 #{176}C ...
... through dialysistubing (Union Carbide Corp., Food Products Division) with an air overpressure of 104 kPa (15 psig).The ultrafiltered serum samples were stored at -60 #{176}C ...
segregation of stimulus phase and intensity coding in the cochlear
... display phase-locked responses (17 of 18) had best frequencies from 7 to 9 kHz, but these accounted for only 13.6% of the neurons sensitive to frequencies in this range. Vector strength as a function of a unit's best frequency is plotted for the magnocellular population in Figure 2. (The value chose ...
... display phase-locked responses (17 of 18) had best frequencies from 7 to 9 kHz, but these accounted for only 13.6% of the neurons sensitive to frequencies in this range. Vector strength as a function of a unit's best frequency is plotted for the magnocellular population in Figure 2. (The value chose ...
Dynamics of Propofol-Induced Loss of Consciousness Across
... brain structures (Ching et al., 2010; Cimenser et al., 2011; Lewis et al., 2012; Purdon et al., 2013; Akeju et al., 2014). Human EEG studies show predictable, signature changes during anestheticinduced unconsciousness (Purdon et al., 2013). However, local field potentials (LFPs) and EEG signals are ...
... brain structures (Ching et al., 2010; Cimenser et al., 2011; Lewis et al., 2012; Purdon et al., 2013; Akeju et al., 2014). Human EEG studies show predictable, signature changes during anestheticinduced unconsciousness (Purdon et al., 2013). However, local field potentials (LFPs) and EEG signals are ...
- Valiente Lab
... Schizophrenia is a complex disorder that interferes with the function of several brain systems required for cognition and normal social behaviour. Although the most notable clinical aspects of the disease only become apparent during late adolescence or early adulthood, many lines of evidence suggest ...
... Schizophrenia is a complex disorder that interferes with the function of several brain systems required for cognition and normal social behaviour. Although the most notable clinical aspects of the disease only become apparent during late adolescence or early adulthood, many lines of evidence suggest ...
Clinically oriented anatomy of the brainstem
... 1. the examiner is depending on the subjective patient response. 2. sensory examination should not be pressed if the aptient is fatigued. 3. sensory examination of patient without neurological problem should be abbreviated 4. patient should be tested with their eyes closed or covered ...
... 1. the examiner is depending on the subjective patient response. 2. sensory examination should not be pressed if the aptient is fatigued. 3. sensory examination of patient without neurological problem should be abbreviated 4. patient should be tested with their eyes closed or covered ...
Supplementary Information (doc 464K)
... administration of 2mmol/kg L-cysteine on 0-1hr food intake (Supplementary Fig. 2B). Inhibiting the enzyme γCSE, which catalyzes the production of pyruvate, ammonia and hydrogen sulphide from L-cysteine, with PPG (20, 21) did not attenuate the effect of intraperitoneal administration of 2mmol/kg L-cy ...
... administration of 2mmol/kg L-cysteine on 0-1hr food intake (Supplementary Fig. 2B). Inhibiting the enzyme γCSE, which catalyzes the production of pyruvate, ammonia and hydrogen sulphide from L-cysteine, with PPG (20, 21) did not attenuate the effect of intraperitoneal administration of 2mmol/kg L-cy ...
A Circuit for Detection of Interaural Time Differences in the Brain
... and obviated the difficulties of extracellular recordings in the nucleus laminaris. Action potentials from single neurons in the nucleus laminaris are masked by the overwhelming field potential termed the neurophonic (Sullivan and Konishi, 1986). Similar difficulties have been found in recording fro ...
... and obviated the difficulties of extracellular recordings in the nucleus laminaris. Action potentials from single neurons in the nucleus laminaris are masked by the overwhelming field potential termed the neurophonic (Sullivan and Konishi, 1986). Similar difficulties have been found in recording fro ...
Intrinsic laminar lattice connections in primate visual cortex
... the cytochrome patches but are sufficiently similar to suggest that the two systems may be identical. Nevertheless, as described below, this does not appear to be the case. In order to investigate the relationship between these two labels, alternate 40-pm sections were reacted for HRP and cytochrome ...
... the cytochrome patches but are sufficiently similar to suggest that the two systems may be identical. Nevertheless, as described below, this does not appear to be the case. In order to investigate the relationship between these two labels, alternate 40-pm sections were reacted for HRP and cytochrome ...
Central and peripheral chemoreceptors evoke distinct responses in
... Figure 3. (Opposite.) Recording site locations and response profiles of neurons. (a) Dorsal (top) and isometric (bottom) views of 356 colour-coded spheres indicating the responses and stereotaxic coordinates of neurons tested with sequential stimulation of central and peripheral chemoreceptors. Neur ...
... Figure 3. (Opposite.) Recording site locations and response profiles of neurons. (a) Dorsal (top) and isometric (bottom) views of 356 colour-coded spheres indicating the responses and stereotaxic coordinates of neurons tested with sequential stimulation of central and peripheral chemoreceptors. Neur ...
Methods of Studying The Nervous System
... • Routes of drug administration include intragastrically (stomach), intraperitonally (abdomen), intramuscularly, subcutaneuously, or intravenously • These peripheral routes all suffer from the fact that many drugs cannot pass the blood-brain barrier; • This problem can be overcome administering drug ...
... • Routes of drug administration include intragastrically (stomach), intraperitonally (abdomen), intramuscularly, subcutaneuously, or intravenously • These peripheral routes all suffer from the fact that many drugs cannot pass the blood-brain barrier; • This problem can be overcome administering drug ...
Review Article Regeneration of Zebrafish CNS
... 2.2. Formation of Neural Tube and Generation of A-P and DV Pattern in Spinal Cord. Neural ectoderm once specified would form neural plate and then neural rod and eventually neural tube. Subsequent to neural plate formation, these plates would converge to form neural keel, followed by the formation o ...
... 2.2. Formation of Neural Tube and Generation of A-P and DV Pattern in Spinal Cord. Neural ectoderm once specified would form neural plate and then neural rod and eventually neural tube. Subsequent to neural plate formation, these plates would converge to form neural keel, followed by the formation o ...
Development of replication-defective herpes simplex viral vectors for
... This thesis describes the development of a highly efficient method for in vivo gene silencing in dorsal root ganglia (DRG) using replication-defective herpes simplex viral (HSV1) vectors by identifying and evaluating various approaches to induce RNAi, i.e. expression of individual short-hairpin RNAs ...
... This thesis describes the development of a highly efficient method for in vivo gene silencing in dorsal root ganglia (DRG) using replication-defective herpes simplex viral (HSV1) vectors by identifying and evaluating various approaches to induce RNAi, i.e. expression of individual short-hairpin RNAs ...
Gut Microbiota: A Modulator of Brain Plasticity and Cognitive
... breakdown of pancreatic enzymes which adversely alters gut function [46]. Other age-related factors such a decline in salivary function, digestion, and dentition may also affect the GI microbiome through time [47]. Additionally, age-related neurone degeneration within the enteric nervous system can ...
... breakdown of pancreatic enzymes which adversely alters gut function [46]. Other age-related factors such a decline in salivary function, digestion, and dentition may also affect the GI microbiome through time [47]. Additionally, age-related neurone degeneration within the enteric nervous system can ...
Changes in the connections of the main olfactory bulb after mitral
... mouse were studied with iontophoretic injections of biotinylated dextran amine. To sort efferences from mitral cells and tufted cells, the Purkinje cell degeneration (PCD) mouse was used. This mutant animal undergoes a specific neurodegeneration of mitral cells, whereas tufted cells do not degenerate ...
... mouse were studied with iontophoretic injections of biotinylated dextran amine. To sort efferences from mitral cells and tufted cells, the Purkinje cell degeneration (PCD) mouse was used. This mutant animal undergoes a specific neurodegeneration of mitral cells, whereas tufted cells do not degenerate ...
A zebrafish model of CLN2 disease is deficient in
... Tripeptidyl peptidase 1 (TPP1) deficiency causes CLN2 disease, late infantile (or classic late infantile neuronal ceroid lipofuscinosis), a paediatric neurodegenerative disease of autosomal recessive inheritance. Patients suffer from blindness, ataxia, epilepsy and cognitive defects, with MRI indica ...
... Tripeptidyl peptidase 1 (TPP1) deficiency causes CLN2 disease, late infantile (or classic late infantile neuronal ceroid lipofuscinosis), a paediatric neurodegenerative disease of autosomal recessive inheritance. Patients suffer from blindness, ataxia, epilepsy and cognitive defects, with MRI indica ...
No Binocular Rivalry in the LGN of Alert Macaque Monkeys
... refer here to the physiological ability to drive an LGN cell, and not the perceptual state of the animal.) From human psychophysics (Levelt, 1965), it is known that reducing contrast to one eye during rivalry increases the fraction of time that eye is suppressed. The entire set of seven conditions w ...
... refer here to the physiological ability to drive an LGN cell, and not the perceptual state of the animal.) From human psychophysics (Levelt, 1965), it is known that reducing contrast to one eye during rivalry increases the fraction of time that eye is suppressed. The entire set of seven conditions w ...
Dietary protein for athletes - Inside Outside Wellness Center
... the intensity of the exercise performed by the subjects in studies in which protein requirements were elevated (Friedman and Lemon 1989; Lemon et al. 1992; Meredith et al. 1989; Tarnopolsky et al. 1988, 1992) was greater than that in studies in which requirements were reduced (Butterfield and Callow ...
... the intensity of the exercise performed by the subjects in studies in which protein requirements were elevated (Friedman and Lemon 1989; Lemon et al. 1992; Meredith et al. 1989; Tarnopolsky et al. 1988, 1992) was greater than that in studies in which requirements were reduced (Butterfield and Callow ...
The Morphology of Physiologically Identified GABAergic Neurons in
... reticular nucleus include in their terminal ramifications the dorsal thalamic nucleus from which they receive inputs (Jones, 1975). The thalamocortical axons have been demonstrated to give off collaterals in the reticular nucleus by intracellular injections in relay neurons of the dorsal lateral gen ...
... reticular nucleus include in their terminal ramifications the dorsal thalamic nucleus from which they receive inputs (Jones, 1975). The thalamocortical axons have been demonstrated to give off collaterals in the reticular nucleus by intracellular injections in relay neurons of the dorsal lateral gen ...
Clinical neurochemistry
![](https://commons.wikimedia.org/wiki/Special:FilePath/Neuron_with_mHtt_inclusion.jpg?width=300)
Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.