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Projections from the brain to the spinal cord in the mouse Huazheng
Projections from the brain to the spinal cord in the mouse Huazheng

... were then mounted in a mouse stereotaxic head holder (Kopf Instruments). A 5 µl Hamilton syringe was mounted on a micromanipulator for spinal cord injection. The mouse adaptor was adjusted for optimal exposure of the upper cervical vertebrae. The first and second cervical spinal cord segments were e ...
Long-range GABAergic neurons in the prefrontal cortex modulate
Long-range GABAergic neurons in the prefrontal cortex modulate

... projections from subcortical regions to NAcc elicit aversion. Thus the authors tested whether cortical GABAergic projections could also mediate aversive responses. Indeed, they found that mice refrained from entering a chamber paired with stimulation of GABAergic mPFC fibers in NAcc, suggesting that ...
Effects of acetylcholine on neuronal properties in entorhinal cortex James G. Heys
Effects of acetylcholine on neuronal properties in entorhinal cortex James G. Heys

... there are neurons in the MSDB that express a range of classical neurotransmitters and neurohormones, this review focuses on the population of putative cholinergic neurons expressing choline acetyltransferase (ChAT) and the separate population of GABAergic neurons expressing GAD, which together compr ...
Pergamon - Anatomical Neuropharmacology Unit
Pergamon - Anatomical Neuropharmacology Unit

7 Ghrelin signalling
7 Ghrelin signalling

... First there was the receptor, discovered as the binding site of synthetic compounds that caused the immediate secretion of growth hormone (GH) from the somatotrophic cells of the anterior pituitary. These compounds were developed as potential medicaments aiming to restore body growth (by boosting th ...
Anatomofunctional organization of the ventral primary motor and
Anatomofunctional organization of the ventral primary motor and

... eyes. We further checked whether different types of movements (i.e. scratching, grooming or spontaneous finger flexion movements) were equally effective in triggering neuronal discharge in order to establish whether the activity was related to simple movements or motor acts. Grasping-related respons ...
The Control of Voluntary Eye Movements: New Perspectives
The Control of Voluntary Eye Movements: New Perspectives

... Many important details about this putative gating mechanism remain unknown, but a circuit with these features could account for several properties of pursuit and saccades. If the gating of pursuit and saccades involved shared circuitry in the brain stem, this would provide a straightforward way to c ...
Voltage-Gated Sodium Channels
Voltage-Gated Sodium Channels

... Nav1.6, and Nav1.7 are reduced but to a lesser extent in dorsal root ganglion neurons following injury [15,16]. The injury-mediated loss of mRNA and protein for Nav1.8 and Nav1.9 in axotomized dorsal root ganglion neurons are paralleled by attenuation of their TTX-R currents in these neurons [17–20] ...
Hypocretin-2-Saporin Lesions of the Lateral Hypothalamus Produce
Hypocretin-2-Saporin Lesions of the Lateral Hypothalamus Produce

... determine whether there was a change in the amplitude of the diurnal rhythm of sleep, the ratio of sleep during the light-on period versus the light-off period was calculated (Table 1). ␦ power (0.5– 4 Hz) was calculated using the ICELUS software system (M. Opp, University of Michigan, Ann Arbor, M ...
Voltage-Gated Sodium Channels: Therapeutic Targets
Voltage-Gated Sodium Channels: Therapeutic Targets

The effect of learning on the face selective responses of neurons in
The effect of learning on the face selective responses of neurons in

... responses selective for faces responded much more specifically than this. Further information on and discussion of the extent to which these neurons have selective responses is given by Baylis et al. 1985; and Rolls 1984, 1989a. The non-face stimuli from which the optimal was chosen included sine wa ...
5. Third year activities - LIRA-Lab
5. Third year activities - LIRA-Lab

... neurons discharge during the whole action they code; some are active during the opening of the fingers, some during finger closure, and others only after the contact with the object. A typical example of a grasping neuron is shown in Figure 2. In particular, this neuron fires during precision grip ( ...
On the computational architecture of the neocortex
On the computational architecture of the neocortex

... accurately using chemicals which move both forward and backward through axons has modified and frequently subdivided Brodmann's areas (e.g. the third visual area, Brodmann's area 19, turned out to be composed of more than one area), but the picture of a map-like division of the surface of the brain ...
PVLV: The Primary Value and Learned Value
PVLV: The Primary Value and Learned Value

PLoS Biol. 2016 Oct 10.
PLoS Biol. 2016 Oct 10.

... not even subthreshold [26–28]. One possibility is that NIf is responsive to auditory feedback and that these responses are gated off in NIf-HVC synapses. To test for this possibility, we perturbed birds during song with an auditory stimulus (white noise or zebra finch call) that we time-locked to a ...
A neurocomputational model of the mammalian fear
A neurocomputational model of the mammalian fear

... detailed neurocomputational model. The fear system has been extensively studied; the key brain regions involved have been identified, and theories have been developed regarding their functions [37]. It is a particularly interesting case study because of how well linked it is to learning and memory; ...
Review Article Regeneration of Zebrafish CNS
Review Article Regeneration of Zebrafish CNS

... induce neurogenesis after injury, and hence regain functional loss [9–13]. Understanding such a remarkable ability of endogenous regeneration in zebrafish, coupled with the new genetic tools and the commonality of its CNS architecture with that of other higher vertebrates, would be of major biomedic ...
Sound processing by local neural populations in the
Sound processing by local neural populations in the

... until recently, this has been technically impossible to do in vivo, because electrophysiological recording techniques cannot densely probe neurons at this spatial resolution, while optical techniques to monitor neural physiology have been limited to use at the surface of the tissue. Recently, this h ...
PII: S0006-8993(97) - UCSD Cognitive Science
PII: S0006-8993(97) - UCSD Cognitive Science

... In adult monkeys with dorsal rhizotomies extending from the second cervical ŽC 2 . to the fifth thoracic ŽT5 . vertebrae, cortex deprived of its normal inputs regained responsiveness to inputs conveyed by intact peripheral afferents from the face wT.P. Pons, P.E. Garraghty, A.K. Ommaya, J.H. Kaas, E ...
ARTICULOS PUBLICADOS EN REVISTAS ELECTRÓNICAS:  TRABAJO 1:
ARTICULOS PUBLICADOS EN REVISTAS ELECTRÓNICAS: TRABAJO 1:

... 5-HT can also activate excitatory receptors (5HT2A and 5-HT3) in GABA interneurons (Morales and Bloom, 1997; Jakab and Goldman-Rakic, 2000) to increase a synaptic GABA input onto pyramidal neurons (Tanaka and North, 1993; Zhou and Hablitz, 1999; Férézou et al., 2002) However, despite the wealth of i ...
Lesser
Lesser

... University of Wisconsin–Madison. These investigations used a technique called micromapping to record the electrical activity of small patches of neurons in the brains of rats as they were touched lightly on various parts of their bodies. ...
Long thought to be solely the BRAIN`S COORDINATOR of body
Long thought to be solely the BRAIN`S COORDINATOR of body

Brain Stem Involvement in Immune and Aversive Challenge Jakob Paues
Brain Stem Involvement in Immune and Aversive Challenge Jakob Paues

... ability to recognise “friend from foe”. Thus, all our cells express identificationmarkers to show that they belong to our body and those that cannot identify themselves are readily destroyed by sentinel cells of the immune system. One threat to homeostasis is invading pathogens such as viruses or ba ...
The Origin of Electromyograms - Explanations Based on the
The Origin of Electromyograms - Explanations Based on the

Saccade Target Selection in the Superior - Smith
Saccade Target Selection in the Superior - Smith

... neurons in a single-stimulus task and in the search task to determine the extent to which the detailed knowledge of SC function derived from single-stimulus tasks can be generalized to situations requiring target selection. A second aim is to analyze the time course of target/distractor discriminati ...
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Central pattern generator

Central pattern generators (CPGs) are biological neural networks that produce rhythmic patterned outputs without sensory feedback. CPGs have been shown to produce rhythmic outputs resembling normal ""rhythmic motor pattern production"" even in isolation from motor and sensory feedback from limbs and other muscle targets. To be classified as a rhythmic generator, a CPG requires:1. ""two or more processes that interact such that each process sequentially increases and decreases, and 2. that, as a result of this interaction, the system repeatedly returns to its starting condition.
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