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DNA/Protein structure-function analysis and prediction - IBIVU
... linkers (hinge loops). The interface between domains in the closed monomer is referred to as the C- (closed) interface. Closed monomers may be opened by mildly denaturing conditions or by mutations that destabilize the closed monomer. Open monomers may dimerize by domain swapping. The domain-swapped ...
... linkers (hinge loops). The interface between domains in the closed monomer is referred to as the C- (closed) interface. Closed monomers may be opened by mildly denaturing conditions or by mutations that destabilize the closed monomer. Open monomers may dimerize by domain swapping. The domain-swapped ...
Abstract - WSU Horticulture
... mutants were drastically compromised in their affinity to calmodulin (CaM), but our unpublished data indicated that the synthetic-peptides corresponding to the mutated CaM-binding domains were able to interact with CaM. These results led us to hypothesize that there is an intramolecular interaction ...
... mutants were drastically compromised in their affinity to calmodulin (CaM), but our unpublished data indicated that the synthetic-peptides corresponding to the mutated CaM-binding domains were able to interact with CaM. These results led us to hypothesize that there is an intramolecular interaction ...
How are bacteria different from viruses?
... something else!) What were the symptoms and how was it treated? ...
... something else!) What were the symptoms and how was it treated? ...
Lecture 5 – Prokaryotic cell structures continued
... that are not associated with human cells. These unique molecules are called pathogen-associated molecular patterns. The pilin in bacterial pili binds to pattern-recognition receptors on a variety of defense cells of the body and triggers innate immune defenses such as inflammation, fever, and phagoc ...
... that are not associated with human cells. These unique molecules are called pathogen-associated molecular patterns. The pilin in bacterial pili binds to pattern-recognition receptors on a variety of defense cells of the body and triggers innate immune defenses such as inflammation, fever, and phagoc ...
microbio 1-3 [4-20
... 20. What protein causes transcription to cease when its product is no longer needed? What RNA sequences have a similar purpose in the regulation of biosynthetic enzymes? The repressor is a protein that stops transcription of an unecessary gene by binding to the operator of the operon [the scribe r ...
... 20. What protein causes transcription to cease when its product is no longer needed? What RNA sequences have a similar purpose in the regulation of biosynthetic enzymes? The repressor is a protein that stops transcription of an unecessary gene by binding to the operator of the operon [the scribe r ...
COMPOSITION OF THE GRAM-POSITIVE PLASMA MEMBRANE
... EtNP = phosphoethanolamine. Note that glycerol phosphate and succinate both carry –ve charges. ...
... EtNP = phosphoethanolamine. Note that glycerol phosphate and succinate both carry –ve charges. ...
Peripheral Membrane Interactions Boost the Engagement by an Anti
... The 4E10 antibody displays an extreme breadth of HIV-1 neutralization and therefore constitutes a model system for structure-guided vaccine design and immunotherapeutics. In this regard, the relevance of auto-reactivity with membrane lipids for the biological function and development of this antibod ...
... The 4E10 antibody displays an extreme breadth of HIV-1 neutralization and therefore constitutes a model system for structure-guided vaccine design and immunotherapeutics. In this regard, the relevance of auto-reactivity with membrane lipids for the biological function and development of this antibod ...
NUCLEATED CELLS…EUKARYOTES The Eukaryota is a domain of
... Paramecium are capable of both sexual and asexual reproduction. Asexual reproduction is the most common, and this is accomplished by the organism dividing transversely. The macronucleus elongates and splits. Under ideal conditions, Paramecium can reproduce asexually two or three times a day. Normall ...
... Paramecium are capable of both sexual and asexual reproduction. Asexual reproduction is the most common, and this is accomplished by the organism dividing transversely. The macronucleus elongates and splits. Under ideal conditions, Paramecium can reproduce asexually two or three times a day. Normall ...
Questions. - hrsbstaff.ednet.ns.ca
... Instructions: Read pages 47-49 and answer the following questions in full sentences. 1. What are two functions of the cell membrane? 2. What would happen if something pierced the cell membrane? 3. What would happen if cells could not exchange materials with their environment? 4. Describe the composi ...
... Instructions: Read pages 47-49 and answer the following questions in full sentences. 1. What are two functions of the cell membrane? 2. What would happen if something pierced the cell membrane? 3. What would happen if cells could not exchange materials with their environment? 4. Describe the composi ...
Gemeinsames Kolloquium
... In contrast to other bacteria but similar to chloroplasts, cyanobacteria harbor six internal compartments (thylakoid lumen, thylakoid membrane, cytoplasm, cytoplasmic membrane, periplasm, outer membrane), and all these compartments appear to harbor a defined subset of proteins. It is, however, still ...
... In contrast to other bacteria but similar to chloroplasts, cyanobacteria harbor six internal compartments (thylakoid lumen, thylakoid membrane, cytoplasm, cytoplasmic membrane, periplasm, outer membrane), and all these compartments appear to harbor a defined subset of proteins. It is, however, still ...
Slide ()
... Vectorial discharge of a secretory polypeptide across the ER membrane mediated by a cleavable N-terminal insertion signal. The cotranslational passage of a polypeptide, such as a secretory or lysosomal protein, into the ER lumen is represented in a simplified form that does not include any molecular ...
... Vectorial discharge of a secretory polypeptide across the ER membrane mediated by a cleavable N-terminal insertion signal. The cotranslational passage of a polypeptide, such as a secretory or lysosomal protein, into the ER lumen is represented in a simplified form that does not include any molecular ...
Study Questions for Biophysics: A Physiological Approach
... 6. If membrane electric fields are strong enough to cause molecular dissociation, how do agonists ever bind to membrane protein receptors? 7. During the propagation of the action potential down a membrane by local current circuits, is the downstream channel that opens more likely to be a sodium chan ...
... 6. If membrane electric fields are strong enough to cause molecular dissociation, how do agonists ever bind to membrane protein receptors? 7. During the propagation of the action potential down a membrane by local current circuits, is the downstream channel that opens more likely to be a sodium chan ...
Kingdoms and Domains 18.3
... • Domain of all organisms whose cells have nuclei, including protists, plants, fungi, and animals. ...
... • Domain of all organisms whose cells have nuclei, including protists, plants, fungi, and animals. ...
Fluid Mosaic model
... Fluid Mosaic model The fluid mosaic model describes the structure of _____________________________________ and as the name suggests indicates that the cell membrane is not _________________________. (it has the consistency of olive oil). Functions of the plasma membrane: 1. ______________________ : ...
... Fluid Mosaic model The fluid mosaic model describes the structure of _____________________________________ and as the name suggests indicates that the cell membrane is not _________________________. (it has the consistency of olive oil). Functions of the plasma membrane: 1. ______________________ : ...
Plasma Membrane
... Active transport: molecules move against the concentration gradient (low to high) ...
... Active transport: molecules move against the concentration gradient (low to high) ...
Cell Extraction and Lysis Extraction kits - protein
... the membrane fraction before SDS-PAGE/Western analysis of COX4. A negligible amount of protein was found in all debris fractions. Abbreviations: AchE = acetylcholinesterase, COX4 = cytochrome oxidase subunit 4, hsp90 = heat shock protein 90, M = solubilised membrane protein fraction and H = hydrophi ...
... the membrane fraction before SDS-PAGE/Western analysis of COX4. A negligible amount of protein was found in all debris fractions. Abbreviations: AchE = acetylcholinesterase, COX4 = cytochrome oxidase subunit 4, hsp90 = heat shock protein 90, M = solubilised membrane protein fraction and H = hydrophi ...
I. Characteristics of amino acids and folding of nascent polypeptides
... Post-translational process: After translation of the SS-containing precursor polypeptide, SecA binds to it (at the SS) while in the cytoplasm; an additional chaperone like SecB may also bind to other regions of the polypeptide to keep it from folding. The SecA-precursor protein complex then binds t ...
... Post-translational process: After translation of the SS-containing precursor polypeptide, SecA binds to it (at the SS) while in the cytoplasm; an additional chaperone like SecB may also bind to other regions of the polypeptide to keep it from folding. The SecA-precursor protein complex then binds t ...
Trimeric autotransporter adhesin
![](https://commons.wikimedia.org/wiki/Special:FilePath/Taabasic1.jpg?width=300)
In molecular biology, trimeric autotransporter adhesins (TAAs), are proteins found on the outer membrane of Gram-negative bacteria. Bacteria use TAAs in order to infect their host cells via a process called cell adhesion. TAAs also go by another name, oligomeric coiled-coil adhesins, which is shortened to OCAs. In essence, they are virulence factors, factors that make the bacteria harmful and infective to the host organism.TAAs are just one of many methods bacteria use to infect their hosts, infection resulting in diseases such as pneumonia, sepsis, and meningitis. Most bacteria infect their host through a method named the secretion pathway. TAAs are part of the secretion pathway, to be more specific the type Vc secretion system.Trimeric autotransporter adhesins have a unique structure. The structure they hold is crucial to their function. They all appear to have a head-stalk-anchor structure. Each TAA is made up of three identical proteins, hence the name trimeric. Once the membrane anchor has been inserted into the outer membrane, the passenger domain passes through it into the host extracellular environment autonomously, hence the description of autotransporter. The head domain, once assembled, then adheres to an element of the host extracellular matrix, for example, collagen, fibronectin, etc.