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Fluid Mosaic model
The fluid mosaic model describes the structure of _____________________________________
and as the name suggests indicates that the cell membrane is not _________________________.
(it has the consistency of olive oil).
Functions of the plasma membrane:
1. ______________________ : Contains the contents of the cell
2. ______________________ : Regulates movement of substances in/out of the cell (selectively
permeable)
3. _______________________: Allows cells to identify surrounding cells
4. _______________________: junctions and surfaces to attach to either ________________ or
____________________ ___
5. _______________________: converts a mechanical or chemical stimulus to a cell into a specific
cellular response
6. _______________________: Cells rely on thousands of different enzymes to allow metabolism.
Structure of the cell membrane:
A sandwich of hydrophobic with two slices of hydrophilic !!
The components of the membrane are:
_________________________
____________________________________
_________________________
_____________________________________
Phospholipids: The major component of the cell membrane
_______________________with a phosphate
come together to make a fluid membrane
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Fluid Mosaic Model
A liposome is a small vesicle with an _______________________ compartment surrounded by a
_____________________________.
__________________________ bonds occur between the phosphate heads and keep the phospholipids
together to make a cell membrane.
Integral Proteins:
 Proteins surrounded by phospholipids which go through the membrane
 Functions: serve as ion ________________, _______________________________, or
_______________________.
 Must have hydrophobic and hydrophilic regions
 Can be globular or membrane (other tertiary structures)
Peripheral proteins:
 Proteins which attach to the membrane
 Predominately interact with _______________________________
 Can attach by weak _________________________________
Glycoproteins
 GLYCOPROTEINS found on the _______________________ of the membrane
 Serve as recognition sites for chemicals
 Involved in cell to cell _______________________________
Glycolipids
 Between phospholipids
 Face extracellular fluid and serve as “cell identifiers”
Cholesterol
 Involved in keeping membrane “fluid”
Fluidity: The more fluid the membrane, the easier it is for a protein to change its conformation. Too
much fluidity permits too many molecules to diffuse in and out of a cell.
Factors affecting Fluidity:
1. Temperature: the bilayer becomes more fluid as temperature increases
2. Double bonds: double bonds form kinks in the tail, therefore increasing fluidity.
3. Fatty acid length: Longer fatty acids tails have more intermolecular attractions reducing fluidity
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Fluid Mosaic Model