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LAB 3 Bacterial Staining Techniques II I. Differential Stains: Gram
LAB 3 Bacterial Staining Techniques II I. Differential Stains: Gram

... commonly used in the microbiology laboratory that differentiates bacteria on the basis of their cell wall structure. Most bacteria can be divided into two groups based on the composition of their cell wall: 1) Gram-positive cell walls have a thick peptidoglycan layer beyond the plasma membrane. Char ...
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... is often difficult to distinguish one from another since a single association may have positive or negative depending on the environmental circumstances. The partners that establish a symbiotic association are called host and symbiont. The host organism is defined as the provider of resources or the ...
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... Journal of Applied Microbiology. 83(6): 737-750. Sharp, K., and Walker, H., 2003. A microbiological survey of communal kitchens used by undergraduate students. International Journal of ...
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... blood coagulation to their advantage. Staphylococcus aureus is one of these microorganisms. S. aureus is a bacterium that causes a multitude of infections like wound infections but also lethal diseases such as meningitis and sepsis. Many people get infected with this bacteria. In fact, about 90% of ...
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... medium with peptone, yeast extract and glucose was employed. Incubation withpolymyxin B. Bacteria were suspended in 1 ml10 mM-Tris/HClbuffer, pH 7.2, which, in the case of halophilic bacteria, was supplemented with up to 25% (w/v) NaCl to prevent lysis. Samples (0.25 ml) of this suspension were incu ...
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... medium with peptone, yeast extract and glucose was employed. Incubation withpolymyxin B. Bacteria were suspended in 1 ml10 mM-Tris/HClbuffer, pH 7.2, which, in the case of halophilic bacteria, was supplemented with up to 25% (w/v) NaCl to prevent lysis. Samples (0.25 ml) of this suspension were incu ...
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... Class 5. Oral microbiology – Bacteria causing inflammations and abscesses within the oral cavity; Gram-positive facultative cocci (genus Staphylococcus, Streptococcus and Enterococcus). Identification of staphylococci in selective-differential medium – mannitol salt agar (Chapman’s medium). Mannito ...
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...  Many antibiotics, including penicillins, inhibit the synthesis of cross-links in peptidoglycans, preventing the formation of a functional wall, particularly in gram-positive species.  These drugs are a very selective treatment because they cripple many species of bacteria without affecting humans ...
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... 2.1. Biosynthesis of Kdo2-lipid A E. coli is the most favoured Gram-negative bacterium for studies of LPS biosynthesis. The first stage of the biosynthetic pathway is the synthesis of Kdo2-lipid A [3,13]. The pathway is mediated by nine enzymes (Table 1) and takes place in the cytoplasm and on the in ...
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... strategy for identification of such targets via a bioinformatics approach. In our first study we compared proteins with unknown and hypothetical function of the spirochete Treponema pallidum to five other pathogens also causing chronic or persistent infections in humans (Yersinia pestis, Neisseria g ...
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... • An important feature of nearly all prokaryotic cells is their cell wall, which maintains cell shape, provides physical protection, and prevents the cell from bursting in a hypotonic environment • Eukaryote cell walls are made of cellulose or chitin • Bacterial cell walls contain peptidoglycan, a n ...
LIN, a Novel Type of U-Box/WD40 Protein
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... identify the LIN gene in Medicago truncatula and Lotus japonicus, showing that it codes for a predicted E3 ubiquitin ligase containing a highly conserved U-box and WD40 repeat domains. Ubiquitin-mediated protein degradation is a universal mechanism to regulate many biological processes by eliminatin ...
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... aminoglycosides are frequently used for the treatment of such infection but strains of Pseudomonas aeruginosa and other bacterial species resistant to aminoglycoside are now been reported in Nigeria and this is probably because gentamicin and other aminoglycosides is traditionally considered in this ...
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Trimeric autotransporter adhesin



In molecular biology, trimeric autotransporter adhesins (TAAs), are proteins found on the outer membrane of Gram-negative bacteria. Bacteria use TAAs in order to infect their host cells via a process called cell adhesion. TAAs also go by another name, oligomeric coiled-coil adhesins, which is shortened to OCAs. In essence, they are virulence factors, factors that make the bacteria harmful and infective to the host organism.TAAs are just one of many methods bacteria use to infect their hosts, infection resulting in diseases such as pneumonia, sepsis, and meningitis. Most bacteria infect their host through a method named the secretion pathway. TAAs are part of the secretion pathway, to be more specific the type Vc secretion system.Trimeric autotransporter adhesins have a unique structure. The structure they hold is crucial to their function. They all appear to have a head-stalk-anchor structure. Each TAA is made up of three identical proteins, hence the name trimeric. Once the membrane anchor has been inserted into the outer membrane, the passenger domain passes through it into the host extracellular environment autonomously, hence the description of autotransporter. The head domain, once assembled, then adheres to an element of the host extracellular matrix, for example, collagen, fibronectin, etc.
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