Genome Rearrangements Caused by Depletion of Essential DNA
... suppress the formation of chromosome rearrangements, whole chromosome deletions, and gene conversions. We quantified the levels of each type of mutation in 15 strains that exhibited both elevated levels of spontaneous DNA damage and chromosome rearrangements following the depletion of an essential ge ...
... suppress the formation of chromosome rearrangements, whole chromosome deletions, and gene conversions. We quantified the levels of each type of mutation in 15 strains that exhibited both elevated levels of spontaneous DNA damage and chromosome rearrangements following the depletion of an essential ge ...
Document
... Autosomal genes can also exhibit linkage • Detect linkage by generating a double heterozygote and crossing to homozygous recessive (testcross) ...
... Autosomal genes can also exhibit linkage • Detect linkage by generating a double heterozygote and crossing to homozygous recessive (testcross) ...
1 Depleting gene activities in early Drosophila embryos
... from D. St. Johnston and F. Wirtz-Peitz. This line is homozygous for two insertions of a construct containing the maternal tubulin promoter from αTub67C and the 3' UTR from αTub84B. The difference between MTD-Gal4 and mat-tub-Gal4 driver lines is that mattub-Gal4 does not drive expression during ear ...
... from D. St. Johnston and F. Wirtz-Peitz. This line is homozygous for two insertions of a construct containing the maternal tubulin promoter from αTub67C and the 3' UTR from αTub84B. The difference between MTD-Gal4 and mat-tub-Gal4 driver lines is that mattub-Gal4 does not drive expression during ear ...
Plant–nematode interactions
... Genome-wide approaches with plant-parasitic nematodes Broad investigations of the genomes and gene products of plant-parasitic nematodes are also underway. More than 200 000 nematode ESTs from 28 nematode species, excluding C. elegans but including 19 animal- and seven plant-parasitic nematode speci ...
... Genome-wide approaches with plant-parasitic nematodes Broad investigations of the genomes and gene products of plant-parasitic nematodes are also underway. More than 200 000 nematode ESTs from 28 nematode species, excluding C. elegans but including 19 animal- and seven plant-parasitic nematode speci ...
Incomplete penetrance of MHC susceptibility genes
... of genetically susceptible individuals to exhibit a trait. We define as baseline penetrance that which occurs in genetically identical (monozygotic) twins of an index subject with a major histocompatibility complex (MHC)-associated disease or trait. We consider two mechanisms for incomplete baseline ...
... of genetically susceptible individuals to exhibit a trait. We define as baseline penetrance that which occurs in genetically identical (monozygotic) twins of an index subject with a major histocompatibility complex (MHC)-associated disease or trait. We consider two mechanisms for incomplete baseline ...
Article
... between genes from different species—such incompatible genes are usually called ‘‘speciation genes.’’ In diploid F1 hybrids, which contain a complete haploid genome from each species, the presence of compatible alleles can mask the effects of (recessive) incompatible speciation genes. But in the hap ...
... between genes from different species—such incompatible genes are usually called ‘‘speciation genes.’’ In diploid F1 hybrids, which contain a complete haploid genome from each species, the presence of compatible alleles can mask the effects of (recessive) incompatible speciation genes. But in the hap ...
Genome-wide histone modification patterns in
... multicellular organisms, where it plays a key role in control of cell state inheritance (SCHUETTENGRUBER et al. 2007), but is absent in both S. cerevisiae and S. pombe. Similarly, methylation of H3K9, a modification central to heterochromatin formation and control of transposable elements (GREWAL an ...
... multicellular organisms, where it plays a key role in control of cell state inheritance (SCHUETTENGRUBER et al. 2007), but is absent in both S. cerevisiae and S. pombe. Similarly, methylation of H3K9, a modification central to heterochromatin formation and control of transposable elements (GREWAL an ...
Statistical analysis of DNA microarray data
... photodetector voltage, imbalance in total amount of RNA in each sample, difference in uptaking of the dyes, etc. • The objective is is to adjust the gene expression values of all genes so that the ones that are not really differentially expressed have similar values across the array(s). ...
... photodetector voltage, imbalance in total amount of RNA in each sample, difference in uptaking of the dyes, etc. • The objective is is to adjust the gene expression values of all genes so that the ones that are not really differentially expressed have similar values across the array(s). ...
Article Purifying Selection Maintains Dosage
... genes, dosage imbalances have been avoided entirely by preserving the Y chromosome allele through strong selection (Bellott et al. 2014; Cortez et al. 2014). These recent findings have raised a number of new questions about the selective forces that shape degeneration and gene loss across the Y chro ...
... genes, dosage imbalances have been avoided entirely by preserving the Y chromosome allele through strong selection (Bellott et al. 2014; Cortez et al. 2014). These recent findings have raised a number of new questions about the selective forces that shape degeneration and gene loss across the Y chro ...
The Arabidopsis RAD51 paralogs RAD51B, RAD51D and XRCC2
... mutants refer to those of Arabidopsis. Both rad51c and xrcc3 knockout mutants are hypersensitive to DNA damaging agents and sterile with striking meiotic chromosome fragmentation, suggesting that RAD51C and XRCC3 are involved in mitotic DNA repair by somatic and meiotic recombination (Bleuyard & Whi ...
... mutants refer to those of Arabidopsis. Both rad51c and xrcc3 knockout mutants are hypersensitive to DNA damaging agents and sterile with striking meiotic chromosome fragmentation, suggesting that RAD51C and XRCC3 are involved in mitotic DNA repair by somatic and meiotic recombination (Bleuyard & Whi ...
Microarrays
... microarrays represent another alternative (e.g., xMAP technology from Luminex [15,16])). Even though, all these elements are essential building blocks of a good MDM, most challenging and most important task is to enable and demonstrate that the developed tool can perform as required in the scope of ...
... microarrays represent another alternative (e.g., xMAP technology from Luminex [15,16])). Even though, all these elements are essential building blocks of a good MDM, most challenging and most important task is to enable and demonstrate that the developed tool can perform as required in the scope of ...
Get
... GENEdreams commented “it is the right of every parent to choose whether or not to have a baby with or without a disability and to desire the best possible health outcomes for their children. If most parents decide against having a child with a disability, there will be more money available to help t ...
... GENEdreams commented “it is the right of every parent to choose whether or not to have a baby with or without a disability and to desire the best possible health outcomes for their children. If most parents decide against having a child with a disability, there will be more money available to help t ...
Networks in leaf development
... sequences that promote the expression of FIL throughout the leaf primordium and repress FIL expression on the adaxial side of the leaf primordium. This demonstrates that FIL is actively excluded from the adaxial domain [32]. The role of YABBY genes in abaxial specification is not clear, however, bec ...
... sequences that promote the expression of FIL throughout the leaf primordium and repress FIL expression on the adaxial side of the leaf primordium. This demonstrates that FIL is actively excluded from the adaxial domain [32]. The role of YABBY genes in abaxial specification is not clear, however, bec ...
No more than 14: the end of the amphioxus Hox cluster
... temporal Colinearity. Genes at the 3’ end of the cluster are expressed, and pattern, the anterior end of the embryos, whilst genes at the 5’ end of the cluster pattern the posterior [3]. Mammalian genomes contain four Hox clusters, with a selection of 13 Hox paralogous groups (PG1 to PG13), originat ...
... temporal Colinearity. Genes at the 3’ end of the cluster are expressed, and pattern, the anterior end of the embryos, whilst genes at the 5’ end of the cluster pattern the posterior [3]. Mammalian genomes contain four Hox clusters, with a selection of 13 Hox paralogous groups (PG1 to PG13), originat ...
to the complete text - David Moore`s World of Fungi
... intervals are about the same size then these classes will also contain about the same number of progeny, as in our theoretical example, above. The progeny frequencies can, obviously, be used to calculate the recombination frequencies and map the genes. But there is an important piece of information ...
... intervals are about the same size then these classes will also contain about the same number of progeny, as in our theoretical example, above. The progeny frequencies can, obviously, be used to calculate the recombination frequencies and map the genes. But there is an important piece of information ...
Comparative Analysis Using DNA Microarrays: Sensitivity
... Therefore, to get the most bang for the buck, it is imperative to understand the role of uncertainty in measurement… ...
... Therefore, to get the most bang for the buck, it is imperative to understand the role of uncertainty in measurement… ...
Antibiotic resistance genes and identification of staphylococci
... tetracycline resistance determinants reveals a great diffusion of this type of resistance. The carriage of multiple tet genes was commonly found in individual Gram-positive bacteria (Schwarz et al., 1998; Huys et al., 2005; Rizzotti et al., 2005). The high incidence of tet(K) and tet(M) genes in the ...
... tetracycline resistance determinants reveals a great diffusion of this type of resistance. The carriage of multiple tet genes was commonly found in individual Gram-positive bacteria (Schwarz et al., 1998; Huys et al., 2005; Rizzotti et al., 2005). The high incidence of tet(K) and tet(M) genes in the ...
sacB - GENI
... We have designed the core of a curriculum, based on genetic complementation of defined E. coli mutants, that enables true experimentation in the classroom The modular format allows testing completely different genes every semester but does so with repetitive sets of protocols and materials Consisten ...
... We have designed the core of a curriculum, based on genetic complementation of defined E. coli mutants, that enables true experimentation in the classroom The modular format allows testing completely different genes every semester but does so with repetitive sets of protocols and materials Consisten ...
Flowering-Time Genes Modulate the Response to
... had been introgressed into the Col background (Lee et al. 1993, 1994), was crossed to a different 35S::LFY line generated in the Col background (DW151.2.5C). Except for 35S::LFY transgenics in the Nossen background, typical homozygous 35S::LFY plants in the Col and Ler backgrounds self-fertilize onl ...
... had been introgressed into the Col background (Lee et al. 1993, 1994), was crossed to a different 35S::LFY line generated in the Col background (DW151.2.5C). Except for 35S::LFY transgenics in the Nossen background, typical homozygous 35S::LFY plants in the Col and Ler backgrounds self-fertilize onl ...
gene duplication in the evolution of sexual dimorphism
... whole-body hybridizations. The detection of sex-bias depends on the statistical approach and power of a given experimental design, which may partly explain differences among studies in the number of sex-biased genes identified. Furthermore, because evolutionarily recent gene duplicates are expected ...
... whole-body hybridizations. The detection of sex-bias depends on the statistical approach and power of a given experimental design, which may partly explain differences among studies in the number of sex-biased genes identified. Furthermore, because evolutionarily recent gene duplicates are expected ...
Trachemys scripta elegans Red-Eared Turtle ( Fc)
... events to generate multiple y genes that eventually differentiated into g and ε. It is highly likely that y evolved to ε because of their similar genetic structures. IgG has three constant domains and a hinge region encoded by a separate exon, which has been thought to be condensed into CH2 of IgY ( ...
... events to generate multiple y genes that eventually differentiated into g and ε. It is highly likely that y evolved to ε because of their similar genetic structures. IgG has three constant domains and a hinge region encoded by a separate exon, which has been thought to be condensed into CH2 of IgY ( ...
Essential gene
Essential genes are those genes of an organism that are thought to be critical for its survival. However, being essential is highly dependent on the circumstances in which an organism lives. For instance, a gene required to digest starch is only essential if starch is the only source of energy. Recently, systematic attempts have been made to identify those genes that are absolutely required to maintain life, provided that all nutrients are available. Such experiments have led to the conclusion that the absolutely required number of genes for bacteria is on the order of about 250-300. These essential genes encode proteins to maintain a central metabolism, replicate DNA, translate genes into proteins, maintain a basic cellular structure, and mediate transport processes into and out of the cell. Most genes are not essential but convey selective advantages and increased fitness.