- Cal State LA - Instructional Web Server
... NCBI's sequence databases accept genome data from sequencing projects from around the world and serve as the cornerstone of bioinformatics research. ...
... NCBI's sequence databases accept genome data from sequencing projects from around the world and serve as the cornerstone of bioinformatics research. ...
Microbial Ecology: Where are we now?
... begin with molecular approaches on bacterial characterization (16S rRNA, DGGE, T-RFLP) and a section on typing bacterial pathogens. Followed by the various NGS technologies currently used (targeted amplification, metagenomics, RNA-seq, proteomics, Tn-seq). Included in each section are selected examp ...
... begin with molecular approaches on bacterial characterization (16S rRNA, DGGE, T-RFLP) and a section on typing bacterial pathogens. Followed by the various NGS technologies currently used (targeted amplification, metagenomics, RNA-seq, proteomics, Tn-seq). Included in each section are selected examp ...
The Human Genome Project: Genetic Screening and the
... growing hair, while others are responsible for fighting off disease. These cells work together, enabling our bodies to act as a single entity-the human being.'0 But how do these cells know which tasks to perform and when? In 1953, James Watson and Francis Crick discovered that within the nucleus of ...
... growing hair, while others are responsible for fighting off disease. These cells work together, enabling our bodies to act as a single entity-the human being.'0 But how do these cells know which tasks to perform and when? In 1953, James Watson and Francis Crick discovered that within the nucleus of ...
Horizontal transfer generates genetic variation in an asexual
... coverage for the 612 type 2 SNPs in LS regions, 25 was the average depth for the 261 type 2 SNPs in the core genome, and 28 was the average depth for the 3031 type 1 SNPs in the whole genome. In sum, the type 2 SNPs in the core genome were dispersed with low depths of coverage in sequence contexts ...
... coverage for the 612 type 2 SNPs in LS regions, 25 was the average depth for the 261 type 2 SNPs in the core genome, and 28 was the average depth for the 3031 type 1 SNPs in the whole genome. In sum, the type 2 SNPs in the core genome were dispersed with low depths of coverage in sequence contexts ...
Complete genome sequence of the thermophilic Thermus sp
... Statement (i.e., a direct report exists in the literature), NAS Non-traceable Author Statement (i.e., not directly observed for the living, isolated sample, but based on a generally accepted property for the species, or anecdotal evidence). These evidence codes are from the Gene Ontology project [65 ...
... Statement (i.e., a direct report exists in the literature), NAS Non-traceable Author Statement (i.e., not directly observed for the living, isolated sample, but based on a generally accepted property for the species, or anecdotal evidence). These evidence codes are from the Gene Ontology project [65 ...
Extrapolation to the whole human genome
... density and gene density, as the former type of pseudogenes arises from duplication of the genomic DNA. One could modify such estimates to account for lower gene density on chromosome 22 than on other human chromosomes (Dunham et al., 1999a; Lander et al., 2001; Venter et al., 2001), so the number o ...
... density and gene density, as the former type of pseudogenes arises from duplication of the genomic DNA. One could modify such estimates to account for lower gene density on chromosome 22 than on other human chromosomes (Dunham et al., 1999a; Lander et al., 2001; Venter et al., 2001), so the number o ...
Transposable elements activity reveals punctuated
... new parameter called Density of Insertion (DI), which is the ratio between the number of TE insertions in a genome and its size. We calculated the DI at both divergence thresholds (1%DI and 5%DI). As for mammalian speciation patterns, we also calculated the Rate of Speciation (RS) as the ratio betwe ...
... new parameter called Density of Insertion (DI), which is the ratio between the number of TE insertions in a genome and its size. We calculated the DI at both divergence thresholds (1%DI and 5%DI). As for mammalian speciation patterns, we also calculated the Rate of Speciation (RS) as the ratio betwe ...
Introduction - Stellenbosch University
... 8. thickEnd - The ending position at which the feature is drawn thickly (for example the stop ...
... 8. thickEnd - The ending position at which the feature is drawn thickly (for example the stop ...
Linkage Disequilibrium and Inference of Ancestral
... have been reported that highlight some of the problems and begin to illustrate some of the results of this LD map. Huttley et al. (1999) used data on 5,048 STRs scored in the CEPH families to infer LD within the grandparental generation. They found several regions of the genome in which significant ...
... have been reported that highlight some of the problems and begin to illustrate some of the results of this LD map. Huttley et al. (1999) used data on 5,048 STRs scored in the CEPH families to infer LD within the grandparental generation. They found several regions of the genome in which significant ...
Powerpoint summary
... Johann Friedrich Miescher isolated and analyzed DNA as a macromolecule for the first time. ...
... Johann Friedrich Miescher isolated and analyzed DNA as a macromolecule for the first time. ...
(base) sequence of the genome might reflect biological information
... (ProQuest: ... denotes formulae omitted.) 1. INTRODUCTION It was well known that there were structural hierarchies in the genome, such as the chromosome, nucleosome, ORF (open reading frame) and so on [1]. Among them, much attention have been paid to the ORF, and many research projects were being pe ...
... (ProQuest: ... denotes formulae omitted.) 1. INTRODUCTION It was well known that there were structural hierarchies in the genome, such as the chromosome, nucleosome, ORF (open reading frame) and so on [1]. Among them, much attention have been paid to the ORF, and many research projects were being pe ...
Genomic Sequence Data - G3: Genes | Genomes | Genetics
... that may contribute to disease in humans or other organisms21,22. These pathogens are generally isolated from diseased tissue samples and thus are found as subsets of complex metagenomic data that also includes host sequence and, commonly, non-pathogenic commensal microflora. Viral DNA or RNA typica ...
... that may contribute to disease in humans or other organisms21,22. These pathogens are generally isolated from diseased tissue samples and thus are found as subsets of complex metagenomic data that also includes host sequence and, commonly, non-pathogenic commensal microflora. Viral DNA or RNA typica ...
software development and application in bioinformatics: single
... This thesis incorporates two projects, one in assessing software availability and application in detecting SNPs for next generation sequencing, and the other in software engineering of a social networking environment for use in biomedical informatics. SNP Detection: The study on variations in DNA se ...
... This thesis incorporates two projects, one in assessing software availability and application in detecting SNPs for next generation sequencing, and the other in software engineering of a social networking environment for use in biomedical informatics. SNP Detection: The study on variations in DNA se ...
VCS: Tool for Visualizing Copy Number Variation and Single Nucleotide Polymorphism
... filtrated by adjusting the criteria with different log2 ratio values for different research purposes. In addition, user can draw a Manhattan plot which easily can define appropriate significance value, and can perform the comparison among samples selected in this menu. The input file needs matrix fo ...
... filtrated by adjusting the criteria with different log2 ratio values for different research purposes. In addition, user can draw a Manhattan plot which easily can define appropriate significance value, and can perform the comparison among samples selected in this menu. The input file needs matrix fo ...
Query Results
... Currently, only the pair NlaIII-BsmFI is available. In the near future, other enzyme pairs such as the one used in Long-SAGE will be added. ...
... Currently, only the pair NlaIII-BsmFI is available. In the near future, other enzyme pairs such as the one used in Long-SAGE will be added. ...
the list of 56 genes that the American College of Medical Genetics and Genomics
... here as incidental findings, the analysis may not be technically equivalent to examining these genes as a primary finding. For example, clinical sequencing could have areas of diminished or absent coverage in the genes examined for incidental findings that would be filled in by Sanger sequencing or ...
... here as incidental findings, the analysis may not be technically equivalent to examining these genes as a primary finding. For example, clinical sequencing could have areas of diminished or absent coverage in the genes examined for incidental findings that would be filled in by Sanger sequencing or ...
In Silico method for identification of MHC class I
... This study is the first attempt to describe MHC class I like molecules of many mammals, including ones that have not previously been studied, in an in silico manner. The automated BLAST method we describe here consists of a blast search with the sequences of exon2 and exon3 which together form the ...
... This study is the first attempt to describe MHC class I like molecules of many mammals, including ones that have not previously been studied, in an in silico manner. The automated BLAST method we describe here consists of a blast search with the sequences of exon2 and exon3 which together form the ...
"Frontmatter". In: Plant Genomics and Proteomics
... size in plants. Despite this enormous variation in DNA content per cell, it is generally accepted that most plants have about the same number of genes and a similar genetic blueprint controlling growth and development. As indicated in the opening paragraph, the wealth of data for many processes, suc ...
... size in plants. Despite this enormous variation in DNA content per cell, it is generally accepted that most plants have about the same number of genes and a similar genetic blueprint controlling growth and development. As indicated in the opening paragraph, the wealth of data for many processes, suc ...
Two groups of human herpesvirus 6 identified by sequence
... studies of this virus DNA have shown that the organization of conserved genes and their encoded amino acid sequences are more related to those of human cytomegalovirus (HCMV) than those of the other human herpesviruses (Lawrence et al., 1990; Neipel et aL, 1991). However, these viruses are distant r ...
... studies of this virus DNA have shown that the organization of conserved genes and their encoded amino acid sequences are more related to those of human cytomegalovirus (HCMV) than those of the other human herpesviruses (Lawrence et al., 1990; Neipel et aL, 1991). However, these viruses are distant r ...
Exceptionally high levels of recombination
... The first draft of the honey bee genome sequence and improved genetic maps are utilized to analyze a genome displaying 10 times higher levels of recombination (19 cM/Mb) than previously analyzed genomes of higher eukaryotes. The exceptionally high recombination rate is distributed genome-wide, but v ...
... The first draft of the honey bee genome sequence and improved genetic maps are utilized to analyze a genome displaying 10 times higher levels of recombination (19 cM/Mb) than previously analyzed genomes of higher eukaryotes. The exceptionally high recombination rate is distributed genome-wide, but v ...
Evaluation of the phylogenetic position of the planctomycete
... They are supposed to have very strong resolving power in evaluating close and intermediate evolutionary distances, i.e. the relationships between species and between major lineages (Wolf et al., 2002). Besides concatenation of protein sequences, three different methods to infer phylogeny from coding ...
... They are supposed to have very strong resolving power in evaluating close and intermediate evolutionary distances, i.e. the relationships between species and between major lineages (Wolf et al., 2002). Besides concatenation of protein sequences, three different methods to infer phylogeny from coding ...
Biotechnology Timeline
... in science as a child when he received a chemistry set for Christmas. ...
... in science as a child when he received a chemistry set for Christmas. ...
Article A Distinct Mitochondrial Genome with DUI
... posterior probability of 0.99 (figs. 1 and 2). For 16S, these phylogenetic analyses were repeated on the same sequences with the 127-bp indel replaced by a single nucleotide to treat the indel as a single insertion/deletion event rather than an accumulation of events affecting single nucleotides. In ...
... posterior probability of 0.99 (figs. 1 and 2). For 16S, these phylogenetic analyses were repeated on the same sequences with the 127-bp indel replaced by a single nucleotide to treat the indel as a single insertion/deletion event rather than an accumulation of events affecting single nucleotides. In ...
Bioinformatics: Bringing it all together
... needs of bench scientists don't always coincide with those of professional bioinformaticians producing tools for whole-genome analyses. Genome projects require programs that can efficiently, if not very accurately, process huge amounts of sequence data, but the biologist in the lab is often interest ...
... needs of bench scientists don't always coincide with those of professional bioinformaticians producing tools for whole-genome analyses. Genome projects require programs that can efficiently, if not very accurately, process huge amounts of sequence data, but the biologist in the lab is often interest ...
Human Genome Project
The Human Genome Project (HGP) is an international scientific research project with the goal of determining the sequence of chemical base pairs which make up human DNA, and of identifying and mapping all of the genes of the human genome from both a physical and functional standpoint. It remains the world's largest collaborative biological project. The project was proposed and funded by the US government; planning started in 1984, got underway in 1990, and was declared complete in 2003. A parallel project was conducted outside of government by the Celera Corporation, or Celera Genomics, which was formally launched in 1998. Most of the government-sponsored sequencing was performed in twenty universities and research centers in the United States, the United Kingdom, Japan, France, Germany, and China.The Human Genome Project originally aimed to map the nucleotides contained in a human haploid reference genome (more than three billion). The ""genome"" of any given individual is unique; mapping ""the human genome"" involves sequencing multiple variations of each gene.