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the nervous sys. The function of neuron & Glia
the nervous sys. The function of neuron & Glia

... sure the ion concentrations recover to their original quantities, a Na/K pump within the membrane moves Na out and K in. Because the pump is moving ions against their concentration gradients requires energy (breakdown of stored ATP. 2. Recall that after Na channels have been activated and open a few ...
Chapter 39
Chapter 39

... A. A synapse may occur between neurons or a neuron and a muscle cell 1. The neuron that ends at the synapse is the presynaptic neuron; the neuron that begins at a synapse is the postsynaptic neuron 2. Signals across synapses can be electrical or chemical a) Electrical synapses involve very close con ...
Nervous System Student Notes File
Nervous System Student Notes File

... neurotransmitters that open Na+ gates triggering depolarization c) _________________________________________________ (IPSP) are caused by neurotransmitters which open K+ or Cl- gates causing hyperpolarization d) A single EPSP is rarely strong enough to trigger an action potential, although and addit ...
Neurons
Neurons

... • Ca++ entry triggers release of some vesicles of transmitter chemical • Transmitter diffuses across synaptic cleft • Transmitter binds to receptors on surface of postsynaptic cell • Interaction of transmitter and receptor leads to temporary change in postsynaptic cell’s probability of undergoing an ...
Neuronal signaling and synapses
Neuronal signaling and synapses

... *can be small molecules, larger peptides, or diffusible gases *first chemical synapse to be described was the neuromuscular junction (a nervemuscle synapse in which the neurotransmitter is acetylcholine, or Ach) -a single presynaptic terminal (usu. an axon) on the postsynaptic membrane (usu. A dendr ...
Neuron Function 2
Neuron Function 2

... 1. An arriving action potential depolarizes the synaptic knob 2. Ca+2 ions enter the cytoplasm of the synaptic knob. 3. ACh release occurs through diffusion and exocytosis of neurotransmitter vesicles 4. ACh diffuses across the synaptic cleft and binds to receptors on the postsynaptic membrane. ...
13. What determines the magnitude of the graded potential? (p. 240)
13. What determines the magnitude of the graded potential? (p. 240)

... are located) and travel down to the axon terminal where they are housed in vesicles until signaled for release. When the appropriate signal (action potential) arrives, neurotransmitter is released via exocytosis. The neurotransmitter then travels by diffusion to the postsynaptic membrane where it op ...
Anatomy and Physiology 241 Lecture Objectives The Nervous
Anatomy and Physiology 241 Lecture Objectives The Nervous

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PSYCH 2230
PSYCH 2230

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Chapter 12
Chapter 12

... 32. Define the anatomic, chemical, enzymatic, and receptor components of a chemical synapse. 33. Go through the sequence of events that allow an action potential on an axon to be transmitted into a graded potential on a postsynaptic membrane. Excitatory and Inhibitory Postsynaptic Potentials 34. Ind ...
Chapter 10
Chapter 10

... Nerve impulses pass from neuron to neuron at synapses ...
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Signature Assignment, Action Potential Graphing, Biology 231

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... as sclerosis, plaques, or lesions, can slow down or completely prevent the transmission of signals between nerve cells. Messages from the brain and spinal cord cannot reach other parts of the body. Damage, or scarring, occurs in many places throughout the central nervous system, hence the term "Mult ...
chapter29_Sections 6
chapter29_Sections 6

... • Action potentials cannot pass directly from a neuron to another cell • Chemicals relay signals from a neurons (presynaptic cell) to another neuron, muscle or gland (postsynaptic cell) across a fluid-filled synaptic cleft • synapse • Region where a neuron’s axon terminals transmit signals to anothe ...
Neurons and Neurotransmission - Milton
Neurons and Neurotransmission - Milton

... “One-third of humanity has perished from the plague. 2.3 billion people have died, and countless more are quickly moving towards the final stages of the disease. There is reason to believe that in a short time, nearly everyone on Earth will be infected. The virus continues to spread exponentially, a ...
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... • Let’s consider a stimulus at the dendrite of a neuron. The stimulus reaches the dendrite (postsynaptic neuron) from the axon (presynaptic neuron) with the help of a NT. • The NT leads to opening of simple ligand-gated channels that are present in the postsynaptic membrane, either Na+ or K+ channel ...
Synapses and neuronal signalling
Synapses and neuronal signalling

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Nervous System
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How Neurons Talk to Each Other
How Neurons Talk to Each Other

... energy, which is provided by another protein molecule, proton ATPase (V-ATPase), that pumps protons into the vesicles – a process that is fuelled by adenosine triphosphate (ATP). The pumps, in turn, use the resulting concentration gradient for the uptake of neurotransmitters. In addition to these pr ...
Neurones & the Action Potential
Neurones & the Action Potential

... Contribution of Active Transport There are different numbers of potassium ions (K+) and sodium ions (Na+) on either side of the membrane. Even when a nerve cell is not conducting an impulse, for each ATP molecule that’s hydrolysed, it is actively transporting 3 molecules Na+ out of the cell and 2 m ...
bioii ch10 ppt
bioii ch10 ppt

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Assignment: Sensing mechanical changes in firing neurons
Assignment: Sensing mechanical changes in firing neurons

... Volts/meter. When an action potential travels down the axon, deviations from this resting potential in the order of 100 milliVolts occur, causing a strong change in electrical field strength over this membrane. It is our hypothesis that this change in electrical field causes small mechanical deforma ...
Myers Module Four
Myers Module Four

... Neuron stimulation causes a brief change in electrical charge. If strong enough, this produces depolarization and an action potential. This depolarization produces another action potential a little farther along the axon. Gates in this neighbouring area are now open, and sodium ions rush in. The sod ...
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End-plate potential



End plate potentials (EPPs) are the depolarizations of skeletal muscle fibers caused by neurotransmitters binding to the postsynaptic membrane in the neuromuscular junction. They are called ""end plates"" because the postsynaptic terminals of muscle fibers have a large, saucer-like appearance. When an action potential reaches the axon terminal of a motor neuron, vesicles carrying neurotransmitters (mostly acetylcholine) are exocytosed and the contents are released into the neuromuscular junction. These neurotransmitters bind to receptors on the postsynaptic membrane and lead to its depolarization. In the absence of an action potential, acetylcholine vesicles spontaneously leak into the neuromuscular junction and cause very small depolarizations in the postsynaptic membrane. This small response (~0.5mV) is called a miniature end plate potential (MEPP) and is generated by one acetylcholine-containing vesicle. It represents the smallest possible depolarization which can be induced in a muscle.
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