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... inputs; the ratio of excitatory to inhibitory synaptic contacts is ⬃10:1, which is unprecedented in the CNS (71). This pattern of synaptic organization, which results in noise assuming the characteristics of signal, allows hypocretinergic neurons to be easily activated, leading to rapid arousal (71) ...
Action Potential
Action Potential

... They send this information along sensory neurons to the brain or ganglia. • Here interneurons connect sensory and motor neurons or make local connections in the brain and spinal cord. ...
Distribution of GABAergic neurons and axon terminals in the
Distribution of GABAergic neurons and axon terminals in the

... Neurons that utilize the neurotransmitter y-aminobutyric acid (GABA) appear to play an important role in generating many of the receptive field properties that distinguish neurons in the striate cortex from those in the lateral geniculate nucleus. When the inhibitory effects of GABA are blocked by t ...
Role of Nitric Oxide on Dopamine Release and Morphine
Role of Nitric Oxide on Dopamine Release and Morphine

... potential failures (Klyachko et al., 2001). These mechanisms may explain how NO modulates DA in NA. However, IbTx known as a BK channel blocker, does not inhibit frequency-dependent effects of SIN-1 (NO donor) on DA release in NA. Several studies reported that NO-mediated DA release was independent ...
Effects of acetylcholine on neuronal properties in entorhinal cortex James G. Heys
Effects of acetylcholine on neuronal properties in entorhinal cortex James G. Heys

... septum and the vertical limb of the diagonal band of Broca (MSDB). To understand how cholinergic neurotransmission can modulate behavior, research has been directed toward identification of the specific cellular mechanisms in EC that can be modulated through cholinergic activity. This review focuses ...
Electrical Interactions via the Extracellular Potential Near Cell Bodies
Electrical Interactions via the Extracellular Potential Near Cell Bodies

... cable theory. Second, we used those currents to compute the extracellular potentials. Third, we used the computed extracellular potentials to compute the transmembrane potential of a cable passing by the cell. Transmembrane currents were first calculated following standard one-dimensional cable theo ...
Forecasting & Demand Planner Module 4 – Basic Concepts
Forecasting & Demand Planner Module 4 – Basic Concepts

... Semiconductors, BP&A Planning, 2003-01-29 ...
THE METABOLISM OF GAMMA AMINOBUTYRIC
THE METABOLISM OF GAMMA AMINOBUTYRIC

... extracts could synthesize about 100 µµmoles of GABA/cm axon/hour while the value for excitatory extracts was about 9 (4) . These values were determined using an assay in which we measured the production of radioactive GABA from high specific-activity glutamate-U- 14 C using an ionexchange procedure ...
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36_LectureSlidesAdde..

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Fine-scale specificity of cortical networks depends on inhibitory cell
Fine-scale specificity of cortical networks depends on inhibitory cell

... of the synaptic currents recorded in neuron pairs can be used to determine whether they share common input on a fine spatial scale. This study showed that fine-scale specificity of inputs to layer 2/3 pyramidal neurons depends on the laminar source of the excitatory input and differs for excitatory ...
Sense Organs
Sense Organs

... of the brain as having numerous “lines” (nerve fibers) feeding information into it, and each line as being “labeled” to represent a certain modality. All the nerve impulses that arrive at the brain are essentially identical, but impulses arriving on one line have a different meaning than impulses ar ...
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Network Self-Organization Explains the Statistics and

... The information processing abilities of neural circuits arise from their synaptic connection patterns. Understanding the laws governing these connectivity patterns is essential for understanding brain function. The overall distribution of synaptic strengths of local excitatory connections in cortex ...
Severe Reduction of Rat Defensive Behavior to a Predator by
Severe Reduction of Rat Defensive Behavior to a Predator by

... nucleus and anterior hypothalamic area [12,14,22]. Although initial hypothalamic chemical stimulation experiments failed to elicit defensive responses [1], patterns of somatomotor and autonomic responses resembling the behavior of animals facing natural threats have now been obtained from a number o ...
PDF
PDF

... To explore further the biological functions of proNGF in the developing PNS, we studied the effects of a cleavage-resistant form of proNGF on two well-characterised populations of NGFdependent neurons cultured at stages throughout late fetal and early postnatal development. The neurons of the trigem ...
Nerve Cell Communication - URMC
Nerve Cell Communication - URMC

...  Place the pink impulse card on the neuron and move it along the axon to the terminal branches.  When the impulse reaches the terminal branches, the receiving neuron becomes a sending neuron that releases its neurotransmitters to send messages to other neurons. 13. Which part of a neuron receives ...
Nerve Cell Communication - URMC
Nerve Cell Communication - URMC

...  Place the pink impulse card on the neuron and move it along the axon to the terminal branches.  When the impulse reaches the terminal branches, the receiving neuron becomes a sending neuron that releases its neurotransmitters to send messages to other neurons. 13. Which part of a neuron receives ...
Reduced Levels of Acetylcholine Receptor Expression in Chick
Reduced Levels of Acetylcholine Receptor Expression in Chick

... precedes the time of synapse formation in the ciliary ganglion (Jacob, 199 1). In early developing chick embryos, the AON is quite accessible since the nucleus lies bilaterally near the surface along the midline region of the dorsal mesencephalon. For the surgery, a small hole was made in the blunt ...
Congenital blindness affects diencephalic but not mesencephalic
Congenital blindness affects diencephalic but not mesencephalic

... 2006) and project to striate and extrastriate visual areas (White and Munoz 2011). Therefore, the retinotectal system is considered to be part of the visual pathway. Although the superior colliculus is retinotopically organized (DuBois and Cohen 2000; Sylvester et al. 2007; Limbrick-Oldfield et al. ...
How the prefrontal executive got its stripes
How the prefrontal executive got its stripes

... The relational rules of the structural model, and specialized and complementary pathways to distinct prefrontal sectors. (a) Feedback pathways originate in an area with less elaborate laminar structure than the destination (brown neurons); feedforward describes pathways that have the opposite relati ...
Signal Propagation and Logic Gating in Networks of Integrate
Signal Propagation and Logic Gating in Networks of Integrate

... fluctuations around the mean (there are 200 ⫾ 14 connections per neuron) that allow for more cells in higher layers. The number 33 was chosen as a compromise between maximizing the number of neurons in each layer and the number of layers that satisfy the prescribed conditions (sometimes for layer 6, ...
WAPT - Human Anatomy
WAPT - Human Anatomy

... Define the following terms: grey matter, white matter, tract, nerve, nucleus, ganglion, decussation, cortex, central nervous system, peripheral nervous system, autonomic nervous system and somatic nervous system List the components of the central and peripheral nervous systems List the support cells ...
Genesis and Control of the Respiratory Rhythm in Adult
Genesis and Control of the Respiratory Rhythm in Adult

... On the basis of recordings of the activity of brain stem neurons that were rhythmically active in phase with respiration, six different types of neurons have been defined on the basis of their firing patterns, their membrane potential changes, and their synaptic inputs (1, 17). As shown in Fig. 2A, ...
Reverse engineering the lordosis behavior circuit.
Reverse engineering the lordosis behavior circuit.

... two gene products, estrogen receptor-alpha and estrogen receptorbeta, to affect numerous genes (Fig. 2). These estrogen-responsive genes have two properties: estrogens elevate their mRNA levels, and their gene products foster female sex behaviors. One line of reasoning follows: (i) Estrogens turn on ...
WAPT - Human Anatomy
WAPT - Human Anatomy

... Define the following terms: grey matter, white matter, tract, nerve, nucleus, ganglion, decussation, cortex, central nervous system, peripheral nervous system, autonomic nervous system and somatic nervous system List the components of the central and peripheral nervous systems List the support cells ...
Biology: Life on Earth 8/e
Biology: Life on Earth 8/e

... Figure E38-5 (part 1) Biology: Life on Earth 8/e ©2008 Pearson Prentice Hall, Inc. ...
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Neuroanatomy



Neuroanatomy is the study of the anatomy and stereotyped organization of nervous systems. In contrast to animals with radial symmetry, whose nervous system consists of a distributed network of cells, animals with bilateral symmetry have segregated, defined nervous systems, and thus we can make much more precise statements about their neuroanatomy. In vertebrates, the nervous system is segregated into the internal structure of the brain and spinal cord (together called the central nervous system, or CNS) and the routes of the nerves that connect to the rest of the body (known as the peripheral nervous system, or PNS). The delineation of distinct structures and regions of the nervous system has been critical in investigating how it works. For example, much of what neuroscientists have learned comes from observing how damage or ""lesions"" to specific brain areas affects behavior or other neural functions.For information about the composition of animal nervous systems, see nervous system. For information about the typical structure of the human nervous system, see human brain or peripheral nervous system. This article discusses information pertinent to the study of neuroanatomy.
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