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Heterogeneity of GABAergic Cells in Cat Visual Cortex
Heterogeneity of GABAergic Cells in Cat Visual Cortex

... and glutaraldehyde) gave strong background staining. Elution of the antibodies by electrophoresis was difficult in tissue sections fixed with fixatives 1, 2, or 3, which also yielded inconsistent immunocytochemical reactions for some antisera, most notably those against GAD and VIP. ...
Excitation of Ventral Tegmental Area Dopaminergic and
Excitation of Ventral Tegmental Area Dopaminergic and

... This work was supported by a grant from the Medical Faculty of the Heinrich-Heine University (R.E.B). We thank Dr. Robert McCarley, Dr. Mahesh Thakkar, and Dr. Radhika Basheer for helpful comments on this manuscript and Claudia Wittrock and Annette Scherer for excellent technical assistance. Corresp ...
- Wiley Online Library
- Wiley Online Library

... Wiederanders, 1994). In a previous study (Nakanishi et al., 1994), we found that CE was greatly expressed in both neurons and microglia from the aged rat brain, although it was barely detectable in the normal young rat brain. We also showed the alteration in immunostaining pattern of CE in neurons f ...
Chapter 14 PowerPoint - Hillsborough Community College
Chapter 14 PowerPoint - Hillsborough Community College

... • Two arms of ANS: – Parasympathetic division: promotes maintenance functions, conserves energy – Sympathetic division: mobilizes body during activity ...
Chapter 1: The Muscle Spindle and the Central
Chapter 1: The Muscle Spindle and the Central

... important of these is the Golgi tendon organ (GTO). The GTO lies within tendinous muscle tissue. Each GTO is connected in series with small bundles of extrafusal muscle fibers (10 to 15). Its primary function is to detect changes in tension on the tendon from muscle pull or from external force (see ...
Lack of response suppression follows repeated ventral tegmental
Lack of response suppression follows repeated ventral tegmental

... main psychoactive component of marijuana, D 9-tetrahydrocannabinol, alters DA activity in the brain reward system originating in the ventral tegmental area (VTA) and projecting to the nucleus accumbens. 11 Accordingly, D 9-tetrahydrocannabinol and other cannabinoids increase VTA DA neuron firing in ...
Anatomy Review
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Central nervous system control of food intake and body
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... Adiposity negative feedback. Introduced more than 50 years ago, the ‘adiposity negative-feedback’ model of energy homeostasis is founded on the premise that circulating signals inform the brain of changes in body fat mass and that in response to this input, the brain mounts adaptive adjustments of e ...
Full version (PDF file)
Full version (PDF file)

... the neocortex of rodents and primates, including humans. The possible neuroprotective role of calretinin and the presumed “resistance” of calretinin-expressing interneurons to various pathological processes are also discussed. Key words Calcium-binding ...
Autonomic nervous system
Autonomic nervous system

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Definition of Neuronal Circuitry Controlling the Activity of Phrenic
Definition of Neuronal Circuitry Controlling the Activity of Phrenic

... Eugene, OR; 1:250) to localize PRV-Bablu or either PRV-152 or PRV-154, respectively. Sections were then washed thoroughly in PBS before being incubated in affinity-purified secondary antibodies raised in donkey that were conjugated to either the C Y3 (red) or C Y2 (green) carbocyanine (Jackson Immun ...
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1 Spiking Neurons
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... These classical results show that the experimenter as an external observer can evaluate and classify neuronal firing by a spike count measure – but is this really the code used by neurons in the brain? In other words, is a neuron which receives signals from a sensory neuron only looking at and react ...
PAIN CONTROL THEORIES
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The Nervous System
The Nervous System

... – Where is respiratory control center? – Where is cardiovascular control center? ...
Dopamine is one of major neurotransmitters in the brain
Dopamine is one of major neurotransmitters in the brain

... Ephrin is a membrane bound ligand that has been shown to play an important role in the specification of neuron targeting in the central nervous system. It interacts with the Eph Receptor in a contact dependant manner. Studies by Feldheim and colleagues indicated that these molecules result in repul ...
embryonic development of the leech nervous system
embryonic development of the leech nervous system

... differentiation of two identified pressure sensory (P) neurons, the Pn and Pv neurons. In the adult leech the P neurons have distinctive cell body locations in the central nervous system (CNS), different peripheral axon branching patterns, and different receptive field territories in the skin. The e ...
Integrator or coincidence detector? The role of the cortical neuron
Integrator or coincidence detector? The role of the cortical neuron

... clarity of the simulation shown in pane/s A and B, the number of PSPs has been kept small and their size large. The of action potentials. Coincidence value of both parameters is not crucial for the qualitative difference observed. detection, by contrast, implies that most PSPs do not actually contri ...
Nerve
Nerve

... Astrocytes • Functions • Help form blood-brain barrier (prevent unwanted materials from entering brain) • Regulate chemical composition of fluid within the brain • Help regulate synaptic transmission • Strengthen and organize nervous tissue in CNS • Replace damaged neurons • Assist with neuronal dev ...
Teacher Materials - Scope, Sequence, and Coordination
Teacher Materials - Scope, Sequence, and Coordination

... own species and others, as well as environmental changes; these responses can be either innate or learned. The broad patterns of behavior exhibited by animals have evolved to ensure reproductive success. Animals often live in unpredictable environments, and so their behavior must be flexible enough ...
Differential responses in three thalamic nuclei in moderately
Differential responses in three thalamic nuclei in moderately

... In vivo imaging techniques have indicated for many years that there is loss of white matter after human traumatic brain injury (TBI) and that the loss is inversely related to cognitive outcome. However, correlated, quantitative evidence for loss of neurons from either the cerebral cortex or the dien ...
lmmunocytochemical Mapping of 18236, A Brain
lmmunocytochemical Mapping of 18236, A Brain

... two-thirds of the lB236 mRNA sequence, and the amino acid sequence deduced from it corresponds to the carboxy-terminal half of the protein. In “Northern” blotting analyses, 1 B236 mRNA is found to be unequally distributed in the adult rat brain, with an abundarice roughly following a caudalto-rostra ...
The Brain of the Planarian as the Ancestor of the Human Brain
The Brain of the Planarian as the Ancestor of the Human Brain

... of the cell membrane, another major advance first developed in the planarian. The planarian eye The pair of planarian eyes is dismissed by most authors of biology textbooks and other scholarly works as mere 'eyespots', yet these organs have remarkable features of primordial true eyes even if a compl ...
A Fast, Reciprocal Pathway between the Lateral Geniculate Nucleus
A Fast, Reciprocal Pathway between the Lateral Geniculate Nucleus

... in oxygen). Temperature, expired CO2, electrocardiogram (ECG), electroencephalogram (EEG), heart rate, and arterial oxygen saturation were monitored continuously. Proper anesthetic depth was assessed by monitoring the EEG for changes in slow-wave/spindle activity and the ECG and expired CO2. If chan ...
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Circumventricular organs

Circumventricular organs (CVOs) are structures in the brain that are characterized by their extensive vasculature and lack of a normal blood brain barrier (BBB). The CVOs allow for the linkage between the central nervous system and peripheral blood flow; additionally they are an integral part of neuroendocrine function. The lack of a blood brain barrier allows the CVOs to act as an alternative route for peptides and hormones in the neural tissue to the peripheral blood stream, while still protecting it from toxic substances. CVOs can be classified into (a) sensory and (b) secretory organs. The sensory organs include the area postrema (AP), the subfornical organ (SFO) and the vascular organ of lamina terminalis. They have the ability to sense plasma molecules and then pass that information into other regions of the brain. Through this, they provide direct information to the autonomic nervous system from the systemic circulation. The secretory organs include the subcommissural organ (SCO), the posterior pituitary, the pineal gland, the median eminence and the intermediate lobe of the pituitary gland. These organs are responsible for secreting hormones and glycoproteins into the peripheral vascular system using feedback from both the brain environment and external stimuli.All of the circumventricular organs, besides the SCO, contain extensive vasculature and fenestrated capillaries which leads to a ‘leaky’ BBB at the site of the organs. Furthermore, all CVOs contain neural tissue, allowing them to play a role in the neuroendocrine system. It is highly debated if the choroid plexus can be included as a CVO. It has a high concentration of fenestrated capillaries, but its lack of neural tissue and its primary role of producing cerebrospinal fluid (CSF) usually excludes the choroid plexus from the CVO classification.Research has also linked CVOs to body fluid regulation, cardiovascular functions, immune responses, thirst, feeding behavior and reproductive behavior.
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