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Dendritic Computation - UCSD Cognitive Science
Dendritic Computation - UCSD Cognitive Science

... dendrites might be beneficial because they enable the spatial separation of inputs to minimize their interaction. In some cases, however, this possible sublinear summation may actually be advantageous (Agmon-Snir et al. 1998, section on coincidence detection in auditory neurons, p. 519) (see Figure ...
The Time Course and Amplitude of EPSPs Evoked at Synapses
The Time Course and Amplitude of EPSPs Evoked at Synapses

... synapses cannot be obtained from this technique, nor can details of convergence of CA3 pyramidal neurons onto single CA1 neurons or of divergence of CA3 neurons into the CA1 field. A knowledge of the amplitudes and time courses of EPSPs evoked at connections formed between single CA3 and CA1 neurons ...
Isoform-specific expression and function of neuregulin
Isoform-specific expression and function of neuregulin

... are expressed, and identical patterns of expression were observed by analysis of β-gal activity and in situ hybridization (Fig. 2). On E6.5 a broad expression was observed, which on E7.5 was restricted to the rostral portion of the embryo (Fig. 2A,B). Sections demonstrated that staining was associat ...
Self-Organizing Visual Cortex Model using Homeostatic Plasticity
Self-Organizing Visual Cortex Model using Homeostatic Plasticity

... other related plots that show the detailed properties of the network during selforganization will be examined. Chapter 5 presents a discussion and analysis of the experiment results and suggestions for future works related to this topic. Chapter 6 presents the conclusions. ...
CNS 424 Block Educational Framework (Week 1)
CNS 424 Block Educational Framework (Week 1)

... Make a list of the components of the system. Review the basic structure of sympathetic trunk. Describe the source of sympathetic system in the neck and make a list of target organs. Describe the Para vertebral sympathetic ganglia in the abdomen, their locations and target organs. Discuss the relatio ...
Neuronal control of leech behavior - Emory Biology
Neuronal control of leech behavior - Emory Biology

... every soma is visible in segmental ganglia. These properties also make optical recording feasible. 5. Long, easily accessible peripheral nerves allow for stimulation of selected neurons and monitoring of neuronal activity with extracellular electrodes. 6. Most relevant electrical parameters can be m ...
Modulation of premotor circuits controlling locomotor activity by
Modulation of premotor circuits controlling locomotor activity by

... or the modulation of locomotor activity. We focused our attention on dissecting the circuit architecture and function of a conserved class of spinal sensory neurons termed cerebrospinal fluid contacting neurons (CSF-cNs). These neurons lie at the interface between the CSF and spinal interneurons con ...
The Role of Mirror Neurons in Movement
The Role of Mirror Neurons in Movement

... performing a similar action. Some premotor (F5) mirror neurons have also been shown to be corticospinal neurons, meaning that spinal targets are also influenced during action observation. Simultaneous electromyography (EMG) recordings from hand and arm muscles provide important evidence that the act ...
Organization of the Honey Bee Mushroom Body
Organization of the Honey Bee Mushroom Body

... gamma lobes specifically support short-term memory, whereas their vertical lobes are essential for long-term memory. Developmental studies have demonstrated that the Drosophila gamma lobe, like its equivalent in the cockroach Periplaneta americana, is supplied by a special class of intrinsic neuron— ...
FREE Sample Here
FREE Sample Here

... b. the creation of chemical transmitters by electrical energy. c. an exchange of positive and negative ions through the cell membrane. Correct: It is through the exchange of negative and positive ions through the cell membrane that a neuron is capable of “firing,” or releasing neurotransmitters. d. ...
- The Human Brain
- The Human Brain

... 'positive' nature (tremor, involuntary movements, . . .) : they involve an excess of activity : such symptoms hardly can arise from destructive pathology . Pathological examination shows eventually destroyed structures, but it does not reveal which of the surviving regions are responsible for the 'p ...
The Influence of Retinal Afferents Upon the Development of Layers
The Influence of Retinal Afferents Upon the Development of Layers

... is a well defined cell-free zone separating lamina A from the perigeniculate nucleus rostrally and from the medial interlaminar nucleus medially. The border between the medial interlaminar nucleus and the C laminae is less clear, as in a normal animal. In contrast to this, on the side of the survivi ...
melanogaster
melanogaster

... that mimic those observed during ight, and octopamine neurons that project to the optic lobes increase in activity during ight. Using genetic tools to manipulate the activity of octopamine neurons, I nd that they are both necessary and sucient for the ight-induced visual boost. This work provid ...
Sample
Sample

... c. an exchange of positive and negative ions through the cell membrane. Correct: It is through the exchange of negative and positive ions through the cell membrane that a neuron is capable of “firing,” or releasing neurotransmitters. d. a molecular chain reaction. Answer: c Diff: 3 Type: MC Page Ref ...
Orexin/Hypocretin: A Neuropeptide at the Interface of Sleep, Energy
Orexin/Hypocretin: A Neuropeptide at the Interface of Sleep, Energy

... states as well as feeding behavior and reward processes. Orexin deficiency results in narcolepsy in humans, dogs, and rodents, suggesting that the orexin system is particularly important for maintenance of wakefulness. In addition, orexin deficiency also cause abnormalities in energy homeostasis and ...
Distribution of Agrin mRNAs in the Chick Embryo Nervous System
Distribution of Agrin mRNAs in the Chick Embryo Nervous System

... agrin-like molecules on the surface of the motor axon (Cohen and Godfrey, 1992). Thus, agrin appears to be involved in neuromuscular synaptogenesis from the time axons contact muscle cells. In addition to agrin’s localization in the synaptic basal lamina, agrin-like proteins are also present in most ...
Propofol Inhibits Neuronal Firing Activities in the Caudal
Propofol Inhibits Neuronal Firing Activities in the Caudal

... Some neuronal firings are of high frequency and some are of low frequency. This indicates that different types of neurons exist in the CVLM and possibly display different firing patterns or functions. For example, much evidence demonstrates that projecting neurons in the CVLM can transmit electrical ...
General and cell type specific mechanisms target
General and cell type specific mechanisms target

... Author for correspondence (e-mail: [email protected]) Accepted 27 July 2006 ...
Estradiol, Substance P, and the PI3K-Akt
Estradiol, Substance P, and the PI3K-Akt

... functioning system for pain perception helps avoid unrecognized infection, injury, and selfmutilation that would reduce one’s lifespan (Dubin & Patapoutian, 2010). However, under certain conditions the system can produce pathological chronic pain that persists beyond the original injury and becomes ...
- Journal of Vestibular Research
- Journal of Vestibular Research

... mammalian species (Table 3). Reactive synaptogenesis has often been suggested as a possible explanation for vestibular compensation; although there is evidence to support its occurrence in frog (for example, 66,67), the evidence from lower mammalian species (for example, 5 ,68) suggests that these c ...
Section Summary
Section Summary

... • The physiological characteristics of the cells that constitute our bodies evolved long ago, when these cells floated freely in the ocean. • In essence, what the evolutionary process has accomplished is the ability to make our own seawater for bathing our cells, to add to this seawater the oxygen a ...
Primate amygdala neurons evaluate the progress of self
Primate amygdala neurons evaluate the progress of self

... sequence ended with a spend choice). However, the relationship between spend probability and sequence progress varied between interest rate conditions, reflecting the animals’ preferences for different sequence lengths (Figure 1C). The animals typically preferred shorter sequences when interest was ...
Neural Networks
Neural Networks

... SNIPE: This manuscript frequently incorporates Snipe. Shaded Snipe-paragraphs like this one are scattered among large parts of the manuscript, providing information on how to implement their context in Snipe. This also implies that those who do not want to use Snipe, just have to skip the shaded Sn ...
Prefrontal Projections to the Thalamic Reticular Nucleus
Prefrontal Projections to the Thalamic Reticular Nucleus

... Surgical procedures. One week after the MRI, the monkeys were anesthetized with ketamine hydrochloride (10 –15 mg/kg, i.m.) followed by gas anesthetic (isoflurane), until a surgical level of anesthesia was accomplished. Surgery was performed under aseptic conditions while heart rate, muscle tone, re ...
Table of Contents
Table of Contents

... are mediated by the GABAA receptor, a GABA-gated chloride channel (Schofield et al., 1987). In vertebrate neurons, chloride ions are pumped out of the cell; thus, activation of GABA receptors will permit chloride to diffuse into the cell, hyperpolarize the membrane and decrease the excitability of t ...
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Circumventricular organs

Circumventricular organs (CVOs) are structures in the brain that are characterized by their extensive vasculature and lack of a normal blood brain barrier (BBB). The CVOs allow for the linkage between the central nervous system and peripheral blood flow; additionally they are an integral part of neuroendocrine function. The lack of a blood brain barrier allows the CVOs to act as an alternative route for peptides and hormones in the neural tissue to the peripheral blood stream, while still protecting it from toxic substances. CVOs can be classified into (a) sensory and (b) secretory organs. The sensory organs include the area postrema (AP), the subfornical organ (SFO) and the vascular organ of lamina terminalis. They have the ability to sense plasma molecules and then pass that information into other regions of the brain. Through this, they provide direct information to the autonomic nervous system from the systemic circulation. The secretory organs include the subcommissural organ (SCO), the posterior pituitary, the pineal gland, the median eminence and the intermediate lobe of the pituitary gland. These organs are responsible for secreting hormones and glycoproteins into the peripheral vascular system using feedback from both the brain environment and external stimuli.All of the circumventricular organs, besides the SCO, contain extensive vasculature and fenestrated capillaries which leads to a ‘leaky’ BBB at the site of the organs. Furthermore, all CVOs contain neural tissue, allowing them to play a role in the neuroendocrine system. It is highly debated if the choroid plexus can be included as a CVO. It has a high concentration of fenestrated capillaries, but its lack of neural tissue and its primary role of producing cerebrospinal fluid (CSF) usually excludes the choroid plexus from the CVO classification.Research has also linked CVOs to body fluid regulation, cardiovascular functions, immune responses, thirst, feeding behavior and reproductive behavior.
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