
1 Introduction to Neurobiology Rudolf Cardinal NST 1B
... is required to bring the neuron to threshold and fire an AP. However, if enough EPSPs arrive at the neuron and are close enough to each other in space and time (and overcome any inhibition from IPSPs) they may sum and trigger an AP. In this way the postsynaptic neuron can integrate information from ...
... is required to bring the neuron to threshold and fire an AP. However, if enough EPSPs arrive at the neuron and are close enough to each other in space and time (and overcome any inhibition from IPSPs) they may sum and trigger an AP. In this way the postsynaptic neuron can integrate information from ...
View Full PDF - Biochemical Society Transactions
... determine the exact function of UCP2, it nonetheless suggests that UCP2 can fulfil more general functions than U C P l and UCP3. T h e role of UCP2 has yet to be fully delineated, even though two recent studies carried out in UCP2-- mice have suggested that this protein could be involved in the prod ...
... determine the exact function of UCP2, it nonetheless suggests that UCP2 can fulfil more general functions than U C P l and UCP3. T h e role of UCP2 has yet to be fully delineated, even though two recent studies carried out in UCP2-- mice have suggested that this protein could be involved in the prod ...
What are the physical and perceptual dimensions of light
... “Body Worlds and the Brain is now at Science World at TELUS World of Science for a limited time. This all-new version of Dr. Gunther von Hagens’ world-famous exhibition looks at the body in a previously unseen way! With over 200 authentic human specimens, and highlights on recent neuroscience findin ...
... “Body Worlds and the Brain is now at Science World at TELUS World of Science for a limited time. This all-new version of Dr. Gunther von Hagens’ world-famous exhibition looks at the body in a previously unseen way! With over 200 authentic human specimens, and highlights on recent neuroscience findin ...
File chapter 2 vocab pp
... electrical impulse generated by the movement of positively charged atoms in and out of channels in the axon’s membrane. ...
... electrical impulse generated by the movement of positively charged atoms in and out of channels in the axon’s membrane. ...
Session 3
... •Photoreceptors sense light through phototransduction. •They are located at the back of the eye, next to the pigment cells which prevent light scattering and are involved in metabolic maintenance of the photoreceptors. •Two major types: •Rods: Rod shaped, very sensitive to light, low acuity, slow te ...
... •Photoreceptors sense light through phototransduction. •They are located at the back of the eye, next to the pigment cells which prevent light scattering and are involved in metabolic maintenance of the photoreceptors. •Two major types: •Rods: Rod shaped, very sensitive to light, low acuity, slow te ...
NGF is the trophic factor that promotes cell survival
... The apoptotic pathway is conserved in worms and humans ...
... The apoptotic pathway is conserved in worms and humans ...
nervous system physiology 1
... long axons: Axonal Projection Neurons = principal neurons or Golgi type I cells short axons restricted to one region of the brain = interneurons/intrinsic neurons or Golgi type II cells absence of a conventional axon – anaxonal neurons (e.g. amacrine cell in the retina - from the Greek for “no large ...
... long axons: Axonal Projection Neurons = principal neurons or Golgi type I cells short axons restricted to one region of the brain = interneurons/intrinsic neurons or Golgi type II cells absence of a conventional axon – anaxonal neurons (e.g. amacrine cell in the retina - from the Greek for “no large ...
Diseases and Disorders of the Nervous System
... have residual neurological deficit & > 25% require chronic care • Includes all disorders in which an area of the brain is transiently or permanently affected by ischemia or bleeding and one or more of the cerebral blood vessels are involved in the pathological process • Ischemic stroke: accounts for ...
... have residual neurological deficit & > 25% require chronic care • Includes all disorders in which an area of the brain is transiently or permanently affected by ischemia or bleeding and one or more of the cerebral blood vessels are involved in the pathological process • Ischemic stroke: accounts for ...
Unit 3A: Neural Processing and the Endocrine System Introduction
... 2. Biological psychologists study the linkage and interplay between the body and the mind. 3. Even more broadly, there is a biopsychosocial component. This concept believes we do the things we do because of (1) our bodies, (2) our minds or thinking, and (3) the culture that we live in. Neurons 1. Ne ...
... 2. Biological psychologists study the linkage and interplay between the body and the mind. 3. Even more broadly, there is a biopsychosocial component. This concept believes we do the things we do because of (1) our bodies, (2) our minds or thinking, and (3) the culture that we live in. Neurons 1. Ne ...
PDF
... signalling is widely believed to be regulated in an autocrine feedback loop by another Egfr ligand, Spitz, and the Egfr inhibitor Argos. On p. 2893, however, Laura Nilson and colleagues challenge this view by showing that the SpitzArgos feedback loop is not required for dorsal appendage patterning a ...
... signalling is widely believed to be regulated in an autocrine feedback loop by another Egfr ligand, Spitz, and the Egfr inhibitor Argos. On p. 2893, however, Laura Nilson and colleagues challenge this view by showing that the SpitzArgos feedback loop is not required for dorsal appendage patterning a ...
Brain matters in multiple sclerosis
... http://www.nationalmssociety.org/about-multiple-sclerosis/what-we-know-about-ms /what-is-ms/myelin/index.aspx Miller DH, Barkhof F, Frank JA, Parker GJ, Thompson AJ. Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance. Brain. 2002 ...
... http://www.nationalmssociety.org/about-multiple-sclerosis/what-we-know-about-ms /what-is-ms/myelin/index.aspx Miller DH, Barkhof F, Frank JA, Parker GJ, Thompson AJ. Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance. Brain. 2002 ...
PDF
... signalling is widely believed to be regulated in an autocrine feedback loop by another Egfr ligand, Spitz, and the Egfr inhibitor Argos. On p. 2893, however, Laura Nilson and colleagues challenge this view by showing that the SpitzArgos feedback loop is not required for dorsal appendage patterning a ...
... signalling is widely believed to be regulated in an autocrine feedback loop by another Egfr ligand, Spitz, and the Egfr inhibitor Argos. On p. 2893, however, Laura Nilson and colleagues challenge this view by showing that the SpitzArgos feedback loop is not required for dorsal appendage patterning a ...
PDF
... signalling is widely believed to be regulated in an autocrine feedback loop by another Egfr ligand, Spitz, and the Egfr inhibitor Argos. On p. 2893, however, Laura Nilson and colleagues challenge this view by showing that the SpitzArgos feedback loop is not required for dorsal appendage patterning a ...
... signalling is widely believed to be regulated in an autocrine feedback loop by another Egfr ligand, Spitz, and the Egfr inhibitor Argos. On p. 2893, however, Laura Nilson and colleagues challenge this view by showing that the SpitzArgos feedback loop is not required for dorsal appendage patterning a ...
Peripheral Nervous System
... Dendrites- receive messages, impulses, and send them to the cell body. Axons- send messages away from the cell body. ...
... Dendrites- receive messages, impulses, and send them to the cell body. Axons- send messages away from the cell body. ...
Chapter 40
... Short term memory allows recalling information for a few minutes and it may be based on reverberating circuits. ...
... Short term memory allows recalling information for a few minutes and it may be based on reverberating circuits. ...
PNS and Transmission
... Transmission • Transmission is carried out by molecules called neurotransmitters. These are stored in vesicles in the axon terminals. • Impulse reaches terminal opens calcium channels Calcium enters the terminal vesicles move toward membrane for exocytosis neurotransmitters are released and ...
... Transmission • Transmission is carried out by molecules called neurotransmitters. These are stored in vesicles in the axon terminals. • Impulse reaches terminal opens calcium channels Calcium enters the terminal vesicles move toward membrane for exocytosis neurotransmitters are released and ...
Inhibitory Control of Hippocampal Inhibitory Neurons
... Distribution of neurons specialized for inhibiting inhibitory neurons, and their role played in the operation of hippocampus ...
... Distribution of neurons specialized for inhibiting inhibitory neurons, and their role played in the operation of hippocampus ...
Chp 7 (part 1)
... ANATOMY CHP 7 Nervous System I. Introduction A. Nervous System: the master controlling and communication system of the body 1. Every thought, action and emotion reflects its activity 2. Electrical Impulses are used to communicate 3. They are very rapid and have immediate response B. The Nervous Syst ...
... ANATOMY CHP 7 Nervous System I. Introduction A. Nervous System: the master controlling and communication system of the body 1. Every thought, action and emotion reflects its activity 2. Electrical Impulses are used to communicate 3. They are very rapid and have immediate response B. The Nervous Syst ...
Control of Movement
... Partially inactivated voltage-dependent Na and Ca channels -> hyperpolarisation -> activation -> it’s easier to depolarise it -> AP -> inhibit the other cell -> hyperpolarisation etc. ...
... Partially inactivated voltage-dependent Na and Ca channels -> hyperpolarisation -> activation -> it’s easier to depolarise it -> AP -> inhibit the other cell -> hyperpolarisation etc. ...
Function - Webster Elementary School
... Two kinds1. Type I - Inherited genetic condition (mutation) where person’s Pancreas cannot make enough insulin (the hormone that brings glucose sugar from the bloodstream into our cells) - usually shows up early in life 3 – 10 y.o. - Glucose in blood builds up and becomes toxic to organs - Causes se ...
... Two kinds1. Type I - Inherited genetic condition (mutation) where person’s Pancreas cannot make enough insulin (the hormone that brings glucose sugar from the bloodstream into our cells) - usually shows up early in life 3 – 10 y.o. - Glucose in blood builds up and becomes toxic to organs - Causes se ...
November 13th Notes (Nervous System)
... integral part of your body’s communication system. It plays an important role in the smooth functioning of the body. The nervous system is a complex network of cells which are specialized in function. ...
... integral part of your body’s communication system. It plays an important role in the smooth functioning of the body. The nervous system is a complex network of cells which are specialized in function. ...
Unit 3A Notes
... 2. Biological psychologists study the linkage and interplay between the body and the mind. 3. Even more broadly, there is a biopsychosocial component. This concept believes we do the things we do because of (1) our bodies, (2) our minds or thinking, and (3) the culture that we live in. 2. Neurons 1. ...
... 2. Biological psychologists study the linkage and interplay between the body and the mind. 3. Even more broadly, there is a biopsychosocial component. This concept believes we do the things we do because of (1) our bodies, (2) our minds or thinking, and (3) the culture that we live in. 2. Neurons 1. ...
Peripheral nervous system
... • Saltatory connection - action potentials jumping from node to node in myelinated axons ...
... • Saltatory connection - action potentials jumping from node to node in myelinated axons ...
P312Ch04C_BeyondV1
... (From Popular Science, March, 2013) Lobes have been characterized for clarity. You should remember the previous view. This is shown to give you some exposure to the variety of ways the brain areas may be represented. ...
... (From Popular Science, March, 2013) Lobes have been characterized for clarity. You should remember the previous view. This is shown to give you some exposure to the variety of ways the brain areas may be represented. ...
Optogenetics

Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.