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Anatomy and Neuroscience Research Projects for 2013
Anatomy and Neuroscience Research Projects for 2013

... Neural Mechanisms of Bone Pain (Jason Ivanusic) Project 1: Changes in the neuro-chemical phenotype of primary afferent neurons that innervate bone in an animal model of inflammatory bone pain. ................................................................. 21 Project 2: Changes in neurotrophin si ...
Article PDF
Article PDF

Choice Coding in Frontal Cortex during Stimulus
Choice Coding in Frontal Cortex during Stimulus

... specific outcome. In the SO task, the subject was presented with two pictures sequentially and each picture was followed by one of three juices. In the AO task, the subject performed two actions sequentially and each action was followed by one of three juices. The relationship between the predictive ...
Slide 1 - TeacherWeb
Slide 1 - TeacherWeb

... neuron resulting in excitation) or – hyperpolarization (additional negative ions move inside resulting in in hibition). ...
Computational cognitive neuroscience: 10. Prefrontal Cortex (PFC)
Computational cognitive neuroscience: 10. Prefrontal Cortex (PFC)

... At the synapses formed by both of the recurrent excitatory loops there are NMDA and metabotropic glutamate (mGluR) receptors that, once opened by high frequency activity, provide a longer time window of increased excitability so as to keep reverberant activity going. • Recall from the Learning Chapt ...
IV. Model Application: the UAV Autonomous Learning in Unknown
IV. Model Application: the UAV Autonomous Learning in Unknown

... The first and the second authors contributed equally to this work, and serve as co-first authors. ...
damage to oligodendrocytes and axons following endothelin 1
damage to oligodendrocytes and axons following endothelin 1

NIH Public Access
NIH Public Access

... fraction (12/96, 13%) of the neurons showed significant increases in spontaneous firing rate, while 43% (41/96) showed significant decreases (Fig. 1b, c, Supplementary Fig. 1c). The cells with increased firing exhibited narrower spike waveforms than those with decreased firing (Fig. 1c, inset; peak- ...
DNA Replication Precedes Neuronal Cell Death
DNA Replication Precedes Neuronal Cell Death

... fluorescence per nucleus. Thus, a fraction of the cells in Ammon’s horn of patients with Alzheimer’s disease have replicated their genome in the region around the end of the long arm of chromosome 11. To determine whether this apparent DNA replication was unique to chromosome 11, we used a second se ...
Bird Brain: Evolution
Bird Brain: Evolution

... information processing as is performed by the mammalian cortex. Likewise, the avian hyperpallium and arcopallium give rise to major descending projections to premotor and motor neurons of the brain stem and spinal cord, as do mammalian corticobulbar and corticospinal pathways. These avian brain regi ...
the cerebellum - krigolson teaching
the cerebellum - krigolson teaching

... cortical areas. The corticospinal tract contains fast-conducting axons some of which terminate directly on spinal motoneurons while others terminate on spinal interneurons. Groups of cortical neurons can demonstrate firing patterns related to the direction of an intended voluntary movement. Disorder ...
PDF - Molecules and Cells
PDF - Molecules and Cells

... tract of females carrying CG3542-LexA, LexAOP-FLP, ppkGAL4, and UAS-FRT-stop-FRT-mCD8-EGFP. Remarkably, we were only able to detect 2-3 EGFP-positive neurons per female genital tract (Fig. 3F): two in the lateral oviduct (Fig. 3F′) and one in the middle oviduct near the spermatheca (Fig. 3F′′). The ...
Proceedings from the 2015 UK-Korea Neuroscience Symposium
Proceedings from the 2015 UK-Korea Neuroscience Symposium

... controlled method to resolve synapses at the level of LM, termed mammalian GFP reconstitution across synaptic partners (mGRASP), is synapse-specific labeling with two complementary GFP components. mGRASP is based on two non-fluorescent splitGFP fragments (called spGFP1-10 and spGFP11) tethered to sy ...
Auditory Cortical Neurons are Sensitive to Static and Continuously
Auditory Cortical Neurons are Sensitive to Static and Continuously

... 1. The interaural-phase-difference (IPD) sensitivity of single neurons in the primary auditory (AI) cortex of the anesthetized cat was studied at stimulus frequencies ranging from 120 to 2,500 Hz. Best frequencies of the 43 AI cells sensitive to IPD ranged from 190 to 2,400 Hz. 2. A static IPD was p ...
The mechanical control of nervous system development
The mechanical control of nervous system development

... One of these processes turns into an axon, which usually grows over long distances, while the others become dendrites. Forces (tension) might not only be involved in the generation of axons (Bray, 1984). Many neuronal cell types adapt their morphology, and particularly the number, lengths and branch ...
The Neurophysiological Basis of Learning and Memory in Advanced
The Neurophysiological Basis of Learning and Memory in Advanced

... (Figures 24.4A and 24.4B), a muscarinic receptor antagonist that also blocks the synaptic potential at the neuromuscular junctions of the octopus arm.34 Hexamethonium also blocked both spontaneous and evoked spiking activity recorded from the large neuron axonal bundles (Figures 24.4B and 24.4D). As ...
Opposite rheological properties of neuronal microcompartments
Opposite rheological properties of neuronal microcompartments

... power law exponent b (Fig. 3D) of both microcompartments were statistically similar for short (Dt 5 850 ms) and long (Dt 5 12 s) force pulses. These results demonstrate that the mechanical behaviors of somas and neurites are time-scale independent, within the range probed. We then measured the force ...
The Design and Function of Cochlear Implants
The Design and Function of Cochlear Implants

... in the temporal bone above the ear. The signals then pass to an array of electrodes inside the cochlea. Target cells in the spiral ganglion are separated from the electrodes by a bony partition. Scott N.’s device uses the continuous interleaved sampling, or CIS, strategy to convert acoustic signals ...
Processing of complex stimuli and natural scenes in the visual cortex
Processing of complex stimuli and natural scenes in the visual cortex

... artificial laboratory stimuli. Consequently, most experiments conducted in the past decades have relied on using simplified artificial stimuli. Starting with the work of Hubel and Wiesel [3] important insight has been obtained by using these stimuli. Models arising from such studies continue to shap ...
The Peripheral Nervous System
The Peripheral Nervous System

... • These messages are relayed through one of two divisions, the somatic nervous system or the autonomic nervous system. ...
Models of signal processing in human hearing
Models of signal processing in human hearing

... doi:10.1016/j.aeue.2005.03.016 ...
Signals Conveyed in the Pulvinar Pathway from Superior Colliculus
Signals Conveyed in the Pulvinar Pathway from Superior Colliculus

... to the stimulated structure. It is worth noting that, although successful The fixation task (Fig. 2 A) was used to map visual receptive fields, to orthodromic/antidromic activation provides clear evidence of conneccompare visual responsivity under passive (fixation) versus active (sactivity, the fai ...
Document
Document

... If we move our electrode around the module, we will find that these two characteristics— orientation sensitivity and ocular dominance—vary systematically and are arranged at right angles to each other. (See Figure 6.29.) ...
Sensory Pathways
Sensory Pathways

... • Levels of Processing and Motor Control • Integrative centers in the brain • Perform more elaborate processing • As we move from medulla oblongata to cerebral cortex, motor patterns become increasingly complex and variable ...
Combinatorial Marking of Cells and Organelles with Split
Combinatorial Marking of Cells and Organelles with Split

... HSN fluorescence was weak and rarely seen when split GFP was generated from these promoters ...
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Nervous system network models

Network of human nervous system comprises nodes (for example, neurons) that are connected by links (for example, synapses). The connectivity may be viewed anatomically, functionally, or electrophysiologically. These are presented in several Wikipedia articles that include Connectionism (a.k.a. Parallel Distributed Processing (PDP)), Biological neural network, Artificial neural network (a.k.a. Neural network), Computational neuroscience, as well as in several books by Ascoli, G. A. (2002), Sterratt, D., Graham, B., Gillies, A., & Willshaw, D. (2011), Gerstner, W., & Kistler, W. (2002), and Rumelhart, J. L., McClelland, J. L., and PDP Research Group (1986) among others. The focus of this article is a comprehensive view of modeling a neural network (technically neuronal network based on neuron model). Once an approach based on the perspective and connectivity is chosen, the models are developed at microscopic (ion and neuron), mesoscopic (functional or population), or macroscopic (system) levels. Computational modeling refers to models that are developed using computing tools.
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