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cellular mechanisms of classical and operant conditioning A model
cellular mechanisms of classical and operant conditioning A model

... A fundamental problem in neuroscience is to understand events occurring within individual neurons and within networks that contribute to learning and memory. For example, what cellular processes detect the coincidence between stimuli during classical conditioning, or between behavior and consequence ...
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... into three distinct neural phases in which each phase reflects a “state” of the oscillating network rather than a particular configuration of the motor output. In other words, a cycle phase in this context means a recurring episode when one or more groups of neurons in the network discharge a charac ...
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Thalamocortical neuron loss and localized astrocytosis in the Cln3
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... result of a mutation in the CLN3 gene, located in the p12.1 region of chromosome 16 (International Batten Disease Consortium, 1995). This most frequently occurring form of NCL has an age of onset between 4 and 10 years and typically results in premature death before the age of 30 (Gardiner, 2002). T ...
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ANS: c, p. 46, F, LO=2.1, (1) - test bank and solution manual for your
ANS: c, p. 46, F, LO=2.1, (1) - test bank and solution manual for your

... Correct. There are more positively charged ions inside the cell than outside. b) larger than c) negative compared to Incorrect. During resting potential, the inside is more negatively charged. d) smaller than ANS: a, p. 49, C, LO=2.1, (2) APA: LO 1.2 35. When a neuron fires, it fires in a(n) _______ ...
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... town Vilnius, then part of Poland, to work in the University Neurology Clinic. As the tides of war changed, Olszewski was forced to work ‘underground’ in a civilian army hospital, where he was relatively safe from enemy search parties. Firm ties between the Polish neurological community at Vilnius a ...
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... cortex, pre-motor cortex, and portions of the somatosensory dorsal parietal cortex); (ii) the dorsolateral portion of the postcommissural putamen and a small rim of the head of the caudate; and (iii) the lateral two-thirds of the globus pallidus (GPe and GPi) and a small portion of the substantia ni ...
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CREB Regulation of Eukaryotic Gene Expression

... specific function was in the development of learning and memory. Seminal work done by Kandel and coworkers in the sea slug, Aplysia, found that primitive forms of motor neuron memory were dependent on CREB activity [27]. CREB mediates the development of memories by initiating transcription events re ...
The cortical column: a structure without a function
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... also denotes the periodic termination of anatomical projections within or between cortical areas. In many instances, periodic projections have a consistent relationship with some architectural feature, such as the cytochrome oxidase patches in V1 or the stripes in V2. These tissue compartments appea ...
Neural mechanism of rapid eye movement sleep generation
Neural mechanism of rapid eye movement sleep generation

... oscillatory mode occurs because of the inactivation and activation of low threshold calcium channels present in thalamocortical principal relay neurons. The low threshold calcium channels (low threshold or low membrane voltage for opening) conduct calcium current when the neuron is in a hyperpolariz ...
to eat or to sleep? orexin in the regulation of feeding and wakefulness
to eat or to sleep? orexin in the regulation of feeding and wakefulness

... ■ Abstract Orexin-A and orexin-B are neuropeptides originally identified as endogenous ligands for two orphan G-protein–coupled receptors. Orexin neuropeptides (also known as hypocretins) are produced by a small group of neurons in the lateral hypothalamic and perifornical areas, a region classicall ...
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Channelrhodopsin



Channelrhodopsins are a subfamily of retinylidene proteins (rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes. Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants have been cloned from other algal species, and more are expected.
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