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Bad Fish
Bad Fish

... potentials in axons of large neurons obtained from squid in the presence of this new toxin. You found after depolarizing, the membrane potential remained positive for an extended length of time and the repolarization was often extremely ...
Excitable Cells and Action Potentials
Excitable Cells and Action Potentials

... Ranvier. These nodes are very important since they are necessary openings for the ionic fluxes generating a new spike to boost the decrementing voltage of a prior impulse. This happens because these nodes have a high density of Na+ channels but no voltage-gated K+ channels. An AP that is generated, ...
Complex Cell-like Direction Selectivity through Spike
Complex Cell-like Direction Selectivity through Spike

... Synaptic currents in the model were calculated using a kinetic model of synaptic transmission [33] with model parameters fitted to whole-cell recorded AMPA (a-amino3-hydroxy-5- methyl-4-isoxazole proprionic acid) currents (see Methods for more details). Other inputs representing background activity ...
Removing some `A` from AI: Embodied Cultured Networks
Removing some `A` from AI: Embodied Cultured Networks

... shows averaged firing rate over all 60 electrodes following two stimulations separated by a time interval. At short ISI's, the response of the network following stimulation was enhanced; at longer intervals, the response was depressed. Furthermore, the variance of the data for each ISI was relativel ...
Thyroid Hormones
Thyroid Hormones

... increase. Treatment is relatively simple to apply. Due to their hydrophilic nature, they can mix up well in solution. Reduction of congenital hypothyroidism with small amount of medicine in the order of micrograms ...
Slides - Mathematics of Networks meetings
Slides - Mathematics of Networks meetings

... Work started as an individual basic research project, motivated by a critical look at modeling biological neurons, rather than using popular connectionist models Biological characteristics of the model needed to include: - Action potential “Signals” in the form of spikes of fixed amplitude - Modelin ...
class_2015_readinglist
class_2015_readinglist

... leads to more differential responses in more functional modules. We demonstrate that, in a single experiment, a multitude of distinct regions can be identified across the whole brain, even within the visual cortex, including areas V1, V4 and V5. This differentiation is based entirely on the differen ...
An Introduction to the Nervous System
An Introduction to the Nervous System

... the membrane’s permeability to these ions is very low • Na+ has only a small effect on the normal resting potential, making it just ...
Chapter 12 The Nervous System
Chapter 12 The Nervous System

... y All of the information from our senses is sorted and interpreted in the cerebrum. y Controls voluntary muscles that control movement and speech y Memories are stored in this area. y Decisions are made here ...
Transformation from temporal to rate coding in a somatosensory
Transformation from temporal to rate coding in a somatosensory

... An implementation of a POm±cortex phase-locked loop that is consistent with the ®ndings presented here is based on a simple closed-loop thalamocortical circuit20 that includes cortical inhibition20,21, cortical oscillatory mechanisms22±24 and thalamic gating25. Brie¯y, this circuit establishes a neg ...
Functional Connections of the Visual Cortex Studied by Cross
Functional Connections of the Visual Cortex Studied by Cross

... neuronal response properties is a central problem in visual physiology. To this end, numerous studies have been undertaken to determine the neuronal connectivities underlying cortical responses. The cross-correlation technique first introduced into neurophysiology by Perkel et al. ( 1967a, b) presen ...
Electrical Synapses between Dopaminergic Neurons of the
Electrical Synapses between Dopaminergic Neurons of the

... an intercellular communication. Recent studies report the expression of connexins (Cx) in DA neurons in juvenile rats (Leung et al., 2002) but also an absence of dye coupling in these cells (Lin et al., 2003). Thus, gap junctional communication between DA neurons remains to be clarified. Furthermore ...
3-Biological Bases-table - Miami Beach Senior High School
3-Biological Bases-table - Miami Beach Senior High School

... The endocrine system is another type of communication system that uses a set of glands which produce hormones (like neurotransmitters) that circulate through the bloodstream, enabling communication. Hypothalamus- part of the brain that links the brain to the endocrine system through control of the p ...
Neuroscience and Behavior Term Explanation
Neuroscience and Behavior Term Explanation

Memory formation: from network structure to neural dynamics
Memory formation: from network structure to neural dynamics



... Members of a protein family often share a high degree of amino acid similarity, as well as common protein motifs. A comparison of the core amino acids of the KIF21A and KIF21B motor domains to previously identified KLPs reveals that KIF21A and KIF21B are most similar to each other and a Caenorhabdit ...
File
File

... ▪ Parasympathetic Nervous System ▪ division of the autonomic nervous system that calms the body, conserving its energy ...
View PDF - Nedivi Lab
View PDF - Nedivi Lab

... be cell type specific. cpg15 is also expressed when target-derived tro- GPI-linked CPG15 and that the smaller protein is a soluble form of phic support is crucial for protection from apoptosis used to match CPG15. To determine whether both CPG15 forms are expressed in vivo and at neuron number with ...
PDF file
PDF file

... on Hebbian learning — cofiring of the pre-synaptic activity ṗ and the post-synaptic activity y of the firing neuron. It has been proved that the general-purpose DP can incrementally grows a generative DN to simulate any given finite automaton (FA)on the fly, [28], provided that the Z area of the DN ...
SPP 1665: Resolving and manipulating neuronal networks in the
SPP 1665: Resolving and manipulating neuronal networks in the

... The nervous system is vulnerable to perturbations during specific developmental periods. Insults during such susceptible time windows can have long-term consequences, including the development of neurological diseases such as epilepsy. Here we report that a pharmacological intervention timed during ...
Neural and Voluntary Control of Breathing
Neural and Voluntary Control of Breathing

... • Currently, we understand there are three neural circuits (nuclei) within the brain stem which influence breathing – Dorsal respiratory group – Ventral respiratory group – Pontine respiratory group • Higher brain centers may also influence these nuclei in the brain stem to modify breathing // cereb ...
Accurate reconstruction of neuronal morphology
Accurate reconstruction of neuronal morphology

... that can be dissolved in 1M potassium acetate, and slight warming may be required to get the substance fully dissolved. To fill a neuron, biocytin needs to be ejected with current pulses at the end of the recording. Positive current pulses of 200 ms duration and an amplitude of 1 to 4 nA applied for ...
Neural Oscillations
Neural Oscillations

... receive only local inhibition (two spikes instead of four) – Here the timing of I spikes does not affect the range of delays over which the synchrony is stable – System in general is more tricky and can have some weird aperiodic or high frequency solutions – On the other hand non-homogeneous network ...
Stem cell biology and drug discovery | BMC Biology | Full Text
Stem cell biology and drug discovery | BMC Biology | Full Text

... of motor neurons and other neurons in developing mouse spinal cord. They established a key role for sonic hedgehog-regulated signaling, and went on to show that the differentiation of motor neurons could be recapitu­ lated in culture by adding retinoic acid to mouse ESCs to generate spinal cord prog ...
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Channelrhodopsin



Channelrhodopsins are a subfamily of retinylidene proteins (rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes. Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants have been cloned from other algal species, and more are expected.
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