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Direct somatic lineage conversion - Philosophical Transactions of
Direct somatic lineage conversion - Philosophical Transactions of

kwanPNAS08
kwanPNAS08

1. If a significant amount of Cl - entered the body of a motor neuron
1. If a significant amount of Cl - entered the body of a motor neuron

... 68. Roughly 75% of spinal nerves carry only sensory information. 69. The spinal cord is directly connected to the cerebrum. 70. Cutting the ventral roots would affect sensation but not motor control. 71. The spinal cord ends at the level of the S2 vertebra. 72. The spinal cord is primarily composed ...
Modulation of Cortical Activation and Behavioral Arousal by
Modulation of Cortical Activation and Behavioral Arousal by

... pontine tegmentum.14–17 In the brainstem, cholinergic neurons are distributed within the medullary reticular formation from where brainstem and descending projections emerge and within the pontomesencephalic tegmentum in the laterodorsal and pedunculopontine tegmental nuclei (LDTg and PPTg) from whe ...
Sequential Development of Electrical and Chemical Synaptic
Sequential Development of Electrical and Chemical Synaptic

... Neuronal circuits form during embryonic life, even before synapses are completely mature. Developmental changes can be quantitative (e.g., connections become stronger and more reliable) or qualitative (e.g., synapses form, are lost, or switch from electrical to chemical or from excitatory to inhibit ...
The mirror neuron system and the consequences of its
The mirror neuron system and the consequences of its

... dorsolateral prefrontal cortex during imitative learning - there are two functionally divided sectors in the frontal component of the human MNS, of which only one is properly mirror  The so called forward model draws the conclusion that the ventral part might have a functional significance during i ...
Mirror neurons in monkey area F5 do not adapt to the observation of
Mirror neurons in monkey area F5 do not adapt to the observation of

... action stimuli’ has made them unsuitable for repetition suppression studies. However, we have recently established that F5 mirror neurons respond not only to ‘naturalistic’ stimuli, but also to filmed actions36. Hence, we could use a well-controlled stimulus, namely the repeated presentation of one a ...
PPT
PPT

...  Each neuron is connected to other nodes with an associated weight (strength) which typically multiplies the signal transmitted  Each neuron has a single threshold value  Weighted sum of all the inputs coming into the neuron is formed and the threshold is subtracted from this value = activation  ...
5-NeuralNetworks
5-NeuralNetworks

... networks (single layer) developed in the 1950’s. • Backpropagation: More complex algorithm for learning multi-layer neural networks developed in the 1980’s. ...
What's a cerebellar circuit doing in the auditory system?
What's a cerebellar circuit doing in the auditory system?

... information through parallel fiber inputs in a cerebellum-like circuit. Synapses between parallel fibers and their targets show long-term potentiation (LTP) and long-term depression (LTD), whereas those between auditory nerve fibers and their targets do not. This paper discusses the integration of a ...
Jukic et al. SUPPLEMANTARY SUPLEMENTARY METHODS En1+/
Jukic et al. SUPPLEMANTARY SUPLEMENTARY METHODS En1+/

... En1+/Otx2 mutants The generation and genotyping of En1+/Otx2 mice has been reported earlier (Broccoli, et al 1999; Brodski, et al 2003). Mutants were kept on a CD-1 genetic background. For lithium and carbamazepine repetitive OFT experiments mutants were backcrossed for 6 generations to a Black Swis ...
post-peer-review-non-publishers
post-peer-review-non-publishers

... Internal circadian clocks are important regulators of mammalian biology, acting to coordinate physiology and behaviour in line with daily changes in the environment. At present, synchronisation of the circadian system to the solar cycle is believed to rely on a quantitative assessment of total ambie ...
morphometric parameters of the structures of the medulla oblongata
morphometric parameters of the structures of the medulla oblongata

... teratoma are located in their typical places in the medulla oblongata and are presented by spherical undifferentiated nerve cells. The solitary nucleus and spinal nucleus of the trigeminal nerve have not clear contours. These nucleus are presented by spherical and spindle single neurons. The average ...
A visual motion detection circuit suggested by Drosophila
A visual motion detection circuit suggested by Drosophila

... containing 379 neurons and 8,637 chemical synaptic contacts, within the Drosophila optic medulla. By matching reconstructed neurons to examples from light microscopy, we assigned neurons to cell types and assembled a connectome of the repeating module of the medulla. Within this module, we identifie ...
76-4-ET-V1-S1__etvs_..
76-4-ET-V1-S1__etvs_..

... numerous and conspicuous cells forming the bulk of gastrodermis. These resemble the epithelio-muscle cells of epidermis in all respects except that their basal contractile processes are single, much more delicate and oriented at right angles to the long axis of body next to mesogloea, thus forming a ...
part ii: the animal mind - Neural and Mental Evolution
part ii: the animal mind - Neural and Mental Evolution

... Battistuzzi et al., 2004). The archaebacteria are believed to have been chemoautotrophs that obtained substrates and energy from abiotic organic resources of the early Earth and depended mainly on anaerobic metabolism. The proliferation of photoautotrophs, the cyanobacteria (blue-green algae), which ...
Lecta5 - University of Waterloo
Lecta5 - University of Waterloo

... holds a licensed electronic subscription. These materials are provided to HLTH 340 students for their exclusive use though a non-public courseware system (UWLEARN) and the images are restricted to the use of HLTH 340 students. Reproduction, transmittal, copying, or posting of these images by student ...
In a galaxy not too far away - Utrecht University Repository
In a galaxy not too far away - Utrecht University Repository

9.14 Lecture 7: The Neural Tube Forms in the Embryo, and CNS
9.14 Lecture 7: The Neural Tube Forms in the Embryo, and CNS

... There was an amazing evolution of major functions dependent originally on olfactory inputs and their projections to the endbrain: • Learned object preferences; identification of desired (good) and abhored (bad) things • Place learning: Identification and memory of good places and bad places ...
Nerve activates contraction
Nerve activates contraction

... Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings ...
Objectives 35 - U
Objectives 35 - U

... striatum; internal capsule grows between these structures leaving bridges of gray matter - putamen and globus pallidus have different connections, but are physically attached 2. General connections - basal ganglia have few projections downstream to brainstem and spinal cord - instead, they affect mo ...
Thermosensory processing in the Drosophila brain
Thermosensory processing in the Drosophila brain

11 - Dr. Jerry Cronin
11 - Dr. Jerry Cronin

... receptor and acts through an intracellular second messenger • Promotes long-lasting effects • Examples: biogenic amines, neuropeptides, and dissolved gases ...
Histamine reduces firing and bursting of anterior and intralaminar
Histamine reduces firing and bursting of anterior and intralaminar

... The predominating effect of histamine on thalamic neurons consisted in a suppression of the firing rate, accompanied by a reduction of bursts that were possibly induced by low-threshold Ca++ spikes. The inhibition of firing could be caused by a direct postsynaptic hyperpolarization or by a reduction ...
Notes for attendees
Notes for attendees

... O. HUMAN MICROBIOME PROJECT - sum total of all the microbes of human body “the Other Genome” - Major Environmental Factors 1. 800,000,000,000,000 - Cells in Human Body…..American Academy Microbiology 80,000,000,000,000 - Human Cells…..~220 different types 720,000,000,000,000 - Human Microbiome - Bac ...
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Channelrhodopsin



Channelrhodopsins are a subfamily of retinylidene proteins (rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes. Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants have been cloned from other algal species, and more are expected.
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