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Visual pathway class..
Visual pathway class..

... • We do not have a descriptive or mechanistic model that predicts response properties of downstream visual areas, or behavior. • A descriptive model would vastly transform technology: the primate visual system is far superior to anything that engineers can build. • A mechanistic model is the ultimat ...
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... • “Noise…poses a fundamental problem for information processing and affects all aspects of nervous-system function.” (Faisal et al, 2008) • In the context of the “neural code”… – For rate code: “variations in inter-spike intervals might be considered unwanted noise.” – For temporal code: “variabilit ...
Embodied Cognition and Mirror Neurons
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... An overlap between brain areas active in two different tasks does not imply an overlap between the neural mechanisms involved in performing those tasks. Several neural populations coexist in a single brain area, and the results cannot rule out that the observed overlap derives from the activity of t ...
The evolution of nervous system centralization
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Manual for the mind - Hardware
Manual for the mind - Hardware

... Wernicke’s Area through the Temporal, Parietal and Frontal Lobes. Allows for coordinated, comprehensible speech. Damage may result in: - Conduction Aphasia - Where auditory comprehension and speech articulation are preserved, but people find it difficult to repeat heard speech. ...
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Review of Thoracic and Abdominal Autonomics

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Columnar Organization of Dendrites and Axons of Single and
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... recorded around the conditioned neurons (Fig. 2). The authors concluded that only the operant-conditioned neurons possessing significantly increased firing rates take the lead as “master neurons”, that exhibit most prominent volitionally driven modulations in a small neural network. Such on-going pr ...
Smell and Taste
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... inhibition follow the tuning of thalamic inputs, and tighten the tuning of excitatory cells by eliminating responses to stimuli that evoke concurrent inhibition and excitation. Feed-forward inhibition and recurrent excitation are all evoked locally, from V1 cells preferring nearby orientations and f ...
membrane potential
membrane potential

... Figure 37.UN01a ...
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Synaptic gating



Synaptic gating is the ability of neural circuits to gate inputs by either suppressing or facilitating specific synaptic activity. Selective inhibition of certain synapses has been studied thoroughly (see Gate theory of pain), and recent studies have supported the existence of permissively gated synaptic transmission. In general, synaptic gating involves a mechanism of central control over neuronal output. It includes a sort of gatekeeper neuron, which has the ability to influence transmission of information to selected targets independently of the parts of the synapse upon which it exerts its action (see also neuromodulation).Bistable neurons have the ability to oscillate between a hyperpolarized (down state) and a depolarized (up state) resting membrane potential without firing an action potential. These neurons can thus be referred to as up/down neurons. According to one model, this ability is linked to the presence of NMDA and AMPA glutamate receptors. External stimulation of the NMDA receptors is responsible for moving the neuron from the down state to the up state, while the stimulation of AMPA receptors allows the neuron to reach and surpass the threshold potential. Neurons that have this bistable ability have the potential to be gated because outside gatekeeper neurons can modulate the membrane potential of the gated neuron by selectively shifting them from the up state to the down state. Such mechanisms have been observed in the nucleus accumbens, with gatekeepers originating in the cortex, thalamus and basal ganglia.
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