Relationship between codon biased genes, microarray expression
... Comparison of CAI and microarray fluorescence values As 85 % of the genes of the R6 and TIGR4 strains have a similarity above 90 %, and a good correlation (r2=0?99) of CAI values among their homologous genes was observed (data not shown), Cy3- (two replicates) and Cy5- (one replicate) labelled cDNA ...
... Comparison of CAI and microarray fluorescence values As 85 % of the genes of the R6 and TIGR4 strains have a similarity above 90 %, and a good correlation (r2=0?99) of CAI values among their homologous genes was observed (data not shown), Cy3- (two replicates) and Cy5- (one replicate) labelled cDNA ...
High resolution crystal structures of unliganded
... Binding of fatty acyl-CoAs to the ACBP occurs with a very high affinity (KD ¼ 1–5 nM). The 30 -phosphate interactions in the CoA end of the ligand account for 40% of the total binding energy,14,15 and only CoA-derivatized fatty acids are bound to ACBP. In the NMR structure of liganded bovine L-ACBP, ...
... Binding of fatty acyl-CoAs to the ACBP occurs with a very high affinity (KD ¼ 1–5 nM). The 30 -phosphate interactions in the CoA end of the ligand account for 40% of the total binding energy,14,15 and only CoA-derivatized fatty acids are bound to ACBP. In the NMR structure of liganded bovine L-ACBP, ...
Comparison of Protein Active Site Structures for
... ligand-defined binding-sites in the CPASS database, the negative impact on the CPASS computational time, and the minimal benefit to functional identification. As an example, the isolated calcium ion (PDB Het ID: CA) is present in 2887 structures in the PDB, which results in a total of 7811 binding s ...
... ligand-defined binding-sites in the CPASS database, the negative impact on the CPASS computational time, and the minimal benefit to functional identification. As an example, the isolated calcium ion (PDB Het ID: CA) is present in 2887 structures in the PDB, which results in a total of 7811 binding s ...
Chapter 1. introduction
... B. Saponification: hydrolysis by NaOH: Glycerol + Soap C. Hydrolysis by Lipases: Glycerol + Fatty acids D. Wax: Fatty acid ester of an alcohol having a higher carbon number ...
... B. Saponification: hydrolysis by NaOH: Glycerol + Soap C. Hydrolysis by Lipases: Glycerol + Fatty acids D. Wax: Fatty acid ester of an alcohol having a higher carbon number ...
Transgenerational epigenetics in the germline cycle
... Epigenetic mechanisms create variably stable changes in gene expression through the establishment of heritable states of chromatin architecture. While many epigenetic phenomena are, by definition, heritably passed through cell division during animal and plant development, evidence suggests that ‘epi ...
... Epigenetic mechanisms create variably stable changes in gene expression through the establishment of heritable states of chromatin architecture. While many epigenetic phenomena are, by definition, heritably passed through cell division during animal and plant development, evidence suggests that ‘epi ...
Stringent Response in Myxococcus xanthus
... Fruiting body formation Starve for amino acids Accumulation of (p)ppGpp Accumulate (p)ppGpp ??Starve for aa Fruiting bodies Is this a causal relationship? Is there a connection between initiation of fruiting body development and (p)ppGpp accumulation? ...
... Fruiting body formation Starve for amino acids Accumulation of (p)ppGpp Accumulate (p)ppGpp ??Starve for aa Fruiting bodies Is this a causal relationship? Is there a connection between initiation of fruiting body development and (p)ppGpp accumulation? ...
Insulin-like growth factor (IGF) signalling is required for early dorso
... IGF-1R signalling is required for normal anterior and CNS development in zebrafish To further characterise the phenotype of DN-IGF-1R expressing embryos, we examined the expression of a number of genes that are critical for normal neural development and for notochord and somite formation. We initial ...
... IGF-1R signalling is required for normal anterior and CNS development in zebrafish To further characterise the phenotype of DN-IGF-1R expressing embryos, we examined the expression of a number of genes that are critical for normal neural development and for notochord and somite formation. We initial ...
Mutation Analysis of the Ornithine Transcarbamylase (OTC) Gene in
... two known and three novel mutations of the OTC gene in five Japanese patients including two neonatal-onset, one late-onset, and two symptomatic female patients. Known nonsense mutations (c.578G>A and c.421C>T) were detected in a neonatal-onset male and a symptomatic female patient, respectively. Mut ...
... two known and three novel mutations of the OTC gene in five Japanese patients including two neonatal-onset, one late-onset, and two symptomatic female patients. Known nonsense mutations (c.578G>A and c.421C>T) were detected in a neonatal-onset male and a symptomatic female patient, respectively. Mut ...
カイコの油蚕変異体に関する
... by white eggs and eyes and translucent larval skin, results from a single base deletion in an ATP-binding cassette (ABC) transporter gene. In addition, an amino acid transporter is responsible for the os (sex-linked translucent) mutant (Kiuchi et al., 2011). These findings indicate that membrane tra ...
... by white eggs and eyes and translucent larval skin, results from a single base deletion in an ATP-binding cassette (ABC) transporter gene. In addition, an amino acid transporter is responsible for the os (sex-linked translucent) mutant (Kiuchi et al., 2011). These findings indicate that membrane tra ...
Regulatory Genes Controlling MPG7 Expression
... is accomplished by the selective expression of genes required for exogenous nitrogen source utilization only in the absence of glutamine or ammonia (Crawford and Arst, 1993). In Escherichia coli and Salmonella typhimurium, NR is a complex process involving a number of regulatory genes, such as rpoN/ ...
... is accomplished by the selective expression of genes required for exogenous nitrogen source utilization only in the absence of glutamine or ammonia (Crawford and Arst, 1993). In Escherichia coli and Salmonella typhimurium, NR is a complex process involving a number of regulatory genes, such as rpoN/ ...
MOD ODN - rci.rutgers.edu
... (PEI), as the delivery agent and the green fluorescent (GFP) gene as an easily quantified model target. Fluorescence measurements indicate the level of downregulation of GFP, which in turn is dependent on the mechanism of complex formation and dissociation that we have assessed with biophysical meas ...
... (PEI), as the delivery agent and the green fluorescent (GFP) gene as an easily quantified model target. Fluorescence measurements indicate the level of downregulation of GFP, which in turn is dependent on the mechanism of complex formation and dissociation that we have assessed with biophysical meas ...
The sequence of a gene encoding convicilin from pea
... pea seeds, in addition to legumin and vicilin [1]. It can be purified from both legumin and vicilin, and it consists solely of polypeptides of Mr approx. 71 000. It does not thus contain polypeptides found in either of the two major storage proteins [2]. On the other hand, convicilin is antigenicall ...
... pea seeds, in addition to legumin and vicilin [1]. It can be purified from both legumin and vicilin, and it consists solely of polypeptides of Mr approx. 71 000. It does not thus contain polypeptides found in either of the two major storage proteins [2]. On the other hand, convicilin is antigenicall ...
Syntabulin, a motor protein linker, controls dorsal
... disorganized vegetal microtubule array formation, and subsequently displays ventralization (Mei et al., 2009). Furthermore, a ubiquitin ligase, tripartite motif-containing 36 (trim36), is localized to the vegetal cortex of Xenopus oocytes, and when depleted causes defective vegetal microtubule array ...
... disorganized vegetal microtubule array formation, and subsequently displays ventralization (Mei et al., 2009). Furthermore, a ubiquitin ligase, tripartite motif-containing 36 (trim36), is localized to the vegetal cortex of Xenopus oocytes, and when depleted causes defective vegetal microtubule array ...
Nucleic Acids
... 20.1 What Are Nucleosides and Nucleotides? Controlled hydrolysis of nucleic acids yields three types of simpler building blocks: heterocyclic aromatic amine bases, the monosaccharide d-ribose or 2-deoxy-d-ribose (Section 17.3), and phosphate ions. Figure 20.1 shows the five heterocyclic aromatic ami ...
... 20.1 What Are Nucleosides and Nucleotides? Controlled hydrolysis of nucleic acids yields three types of simpler building blocks: heterocyclic aromatic amine bases, the monosaccharide d-ribose or 2-deoxy-d-ribose (Section 17.3), and phosphate ions. Figure 20.1 shows the five heterocyclic aromatic ami ...
A Simple Introduction to NCBI BLAST
... of the model fruit fly Drosophila melanogaster) contains region(s) with sequence similarity to any known genes. The unknown sequence is an 11,000 base pair (bp) fragment of genomic DNA, and the objective of gene annotation is to find and precisely map the coding regions of any genes in this part of ...
... of the model fruit fly Drosophila melanogaster) contains region(s) with sequence similarity to any known genes. The unknown sequence is an 11,000 base pair (bp) fragment of genomic DNA, and the objective of gene annotation is to find and precisely map the coding regions of any genes in this part of ...
Thesis-1965R-K29r
... attempt to obtain information on the structure, composition and function of the nucleolus. Information on the possible connections of the nucleolus with the mitotic cycle and cytoplasm was also obtained. Pub I ications since the year 1959 were consulted. The materials used were chiefly periodicals a ...
... attempt to obtain information on the structure, composition and function of the nucleolus. Information on the possible connections of the nucleolus with the mitotic cycle and cytoplasm was also obtained. Pub I ications since the year 1959 were consulted. The materials used were chiefly periodicals a ...
Finding of a novel fungal immunomodulatory protein coding
... australe hypothetical immunomodulatory protein (right block), inferred from contig c13717 in this study. Key descriptions for each row same as in figure 2. Interestingly, the immunomodulatory protein from Tai. camphoratus was isolated by Sheu et al. (2009) from a mycelium extract and reported as a g ...
... australe hypothetical immunomodulatory protein (right block), inferred from contig c13717 in this study. Key descriptions for each row same as in figure 2. Interestingly, the immunomodulatory protein from Tai. camphoratus was isolated by Sheu et al. (2009) from a mycelium extract and reported as a g ...
Identification of Both Shared and Distinct Proteins in the Major and
... have been identified. Here, the human U11/U12 small nuclear ribonucleoprotein (snRNP), a subunit of the minor (U12-dependent) spliceosome, was isolated. Twenty U11/U12 proteins were identified, including subsets unique to the minor spliceosome or common to both spliceosomes. Common proteins include ...
... have been identified. Here, the human U11/U12 small nuclear ribonucleoprotein (snRNP), a subunit of the minor (U12-dependent) spliceosome, was isolated. Twenty U11/U12 proteins were identified, including subsets unique to the minor spliceosome or common to both spliceosomes. Common proteins include ...
proposal for complex variants
... 1) to reduce the necessity to submit new Genbank sequences for every small change observed within a larger change 2) to allow easy comparison between different complex changes. 3) to provide a description format, which can be generated and interpreted by dedicated software tools, such as Mutalyzer ( ...
... 1) to reduce the necessity to submit new Genbank sequences for every small change observed within a larger change 2) to allow easy comparison between different complex changes. 3) to provide a description format, which can be generated and interpreted by dedicated software tools, such as Mutalyzer ( ...
Evolutionary aspects of recombination in RNA viruses
... genomes of accumulated deleterious changes (Muller, 1964) and to create or spread beneficial combinations of mutations in an efficient manner (Fisher, 1930 ; Muller, 1932), two processes which are not available to clonal organisms. Two distinct but not mutually exclusive types of genetic exchange op ...
... genomes of accumulated deleterious changes (Muller, 1964) and to create or spread beneficial combinations of mutations in an efficient manner (Fisher, 1930 ; Muller, 1932), two processes which are not available to clonal organisms. Two distinct but not mutually exclusive types of genetic exchange op ...
Survey of Conserved Alternative Splicing Events
... any transcript. We compared the exon-intron structures of each transcript and genome and identified AS events. Identification of Conserved AS Events We surveyed for conserved AS events based on the positions of alternatively spliced introns during multiple alignments of amino acid sequences. We used ...
... any transcript. We compared the exon-intron structures of each transcript and genome and identified AS events. Identification of Conserved AS Events We surveyed for conserved AS events based on the positions of alternatively spliced introns during multiple alignments of amino acid sequences. We used ...
Received June 19, 1964.
... nucleotides by the pathway proposed in the Introduction. The observed greater conversion of orotic acid than either aspartic or carbamyl aspartic acids to -RNA is predicted by its position in the metabolic sequence, although comparisons are somewhat difficult because only the DL-forms of the latter ...
... nucleotides by the pathway proposed in the Introduction. The observed greater conversion of orotic acid than either aspartic or carbamyl aspartic acids to -RNA is predicted by its position in the metabolic sequence, although comparisons are somewhat difficult because only the DL-forms of the latter ...