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Lipoic Acid 100 mg The Universal Antioxidant
Lipoic Acid 100 mg The Universal Antioxidant

... carbohydrates and fats, with a particular role in blood glucose disposal. It is also able to scavenge a number of free radicals. As both a fat and water-soluble, sulfur-containing coenzyme, alpha-lipoic acid functions in the body as part of several multi-enzyme complexes located in the mitochondria. ...
LipidCat+AAmetabolism
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... Double bond moves from cis-3,4 to trans-2,3 via 3,2-enoyl-CoA isomerase reaction Further beta oxidation proceeds until we encounter the next double bond; Cis double bonds at even positions get modified by 2,4-dienoyl-CoA reductase from trans,cis-2,4 to trans-3 3,2-enoyl-CoA isomerase moves tra ...
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ATP – The Energy of Life - Liberation Chiropractic and Wellness

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Two-Metal-Ion Catalysis in Adenylyl Cyclase

... structure, ␤-L-2⬘,3⬘-dd-5⬘-ATP appears to bind as a complex with two metal ions. The first metal (metal A) is coordinated by the pro-R oxygen of the ␣ phosphate, a carboxylate oxygen from each of the invariant aspartic acid residues [Asp396 (D396) and D440], and a water molecule. The four ligands fo ...
A Quick Look at Biochemistry: Lipid Metabolism
A Quick Look at Biochemistry: Lipid Metabolism

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Glycolysis



Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+. The free energy released in this process is used to form the high-energy compounds ATP (adenosine triphosphate) and NADH (reduced nicotinamide adenine dinucleotide).Glycolysis is a determined sequence of ten enzyme-catalyzed reactions. The intermediates provide entry points to glycolysis. For example, most monosaccharides, such as fructose and galactose, can be converted to one of these intermediates. The intermediates may also be directly useful. For example, the intermediate dihydroxyacetone phosphate (DHAP) is a source of the glycerol that combines with fatty acids to form fat.Glycolysis is an oxygen independent metabolic pathway, meaning that it does not use molecular oxygen (i.e. atmospheric oxygen) for any of its reactions. However the products of glycolysis (pyruvate and NADH + H+) are sometimes disposed of using atmospheric oxygen. When molecular oxygen is used in the disposal of the products of glycolysis the process is usually referred to as aerobic, whereas if the disposal uses no oxygen the process is said to be anaerobic. Thus, glycolysis occurs, with variations, in nearly all organisms, both aerobic and anaerobic. The wide occurrence of glycolysis indicates that it is one of the most ancient metabolic pathways. Indeed, the reactions that constitute glycolysis and its parallel pathway, the pentose phosphate pathway, occur metal-catalyzed under the oxygen-free conditions of the Archean oceans, also in the absence of enzymes. Glycolysis could thus have originated from chemical constraints of the prebiotic world.Glycolysis occurs in most organisms in the cytosol of the cell. The most common type of glycolysis is the Embden–Meyerhof–Parnas (EMP pathway), which was discovered by Gustav Embden, Otto Meyerhof, and Jakub Karol Parnas. Glycolysis also refers to other pathways, such as the Entner–Doudoroff pathway and various heterofermentative and homofermentative pathways. However, the discussion here will be limited to the Embden–Meyerhof–Parnas pathway.The entire glycolysis pathway can be separated into two phases: The Preparatory Phase – in which ATP is consumed and is hence also known as the investment phase The Pay Off Phase – in which ATP is produced.↑ ↑ 2.0 2.1 ↑ ↑ ↑ ↑ ↑ ↑
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