Ref ID: 368
... toxic forms. We have correlated drug resistance in neuroblastoma (NB) cell lines with mRNA overexpression of g-glutamylcysteine synthetase (g-GCS) and GSH-s-transferase µ (GSTµ), that code for glutathione synthesis and utilization enzymes. METHODS: We studied 20 NB cell lines containing 10 sensitive ...
... toxic forms. We have correlated drug resistance in neuroblastoma (NB) cell lines with mRNA overexpression of g-glutamylcysteine synthetase (g-GCS) and GSH-s-transferase µ (GSTµ), that code for glutathione synthesis and utilization enzymes. METHODS: We studied 20 NB cell lines containing 10 sensitive ...
Biochemistry Biochemistry is the science concerned the chemical
... The aim of the class: the determination of the initial velocity and Michaelis constant in reaction catalysed by saccharase Theoretical basis: the enzyme-catalyzed reaction, the definitions of initial velocity, maximal velocity and Michaelis constant, the Michaelis-Menten equation, the standard units ...
... The aim of the class: the determination of the initial velocity and Michaelis constant in reaction catalysed by saccharase Theoretical basis: the enzyme-catalyzed reaction, the definitions of initial velocity, maximal velocity and Michaelis constant, the Michaelis-Menten equation, the standard units ...
Biochemistry Biochemistry is the science concerned the chemical
... The aim of the class: the determination of the initial velocity and Michaelis constant in reaction catalysed by saccharase Theoretical basis: the enzyme-catalyzed reaction, the definitions of initial velocity, maximal velocity and Michaelis constant, the Michaelis-Menten equation, the standard unit ...
... The aim of the class: the determination of the initial velocity and Michaelis constant in reaction catalysed by saccharase Theoretical basis: the enzyme-catalyzed reaction, the definitions of initial velocity, maximal velocity and Michaelis constant, the Michaelis-Menten equation, the standard unit ...
Identification of GNB – IMViC Tests
... are governed by biological catalysts called enzymes. Fermentations are energy-producing biochemical reactions in which organic molecules serve both as electron acceptors and donors. The ability of microorganisms to ferment carbohydrates and the types of products formed are very useful in identificat ...
... are governed by biological catalysts called enzymes. Fermentations are energy-producing biochemical reactions in which organic molecules serve both as electron acceptors and donors. The ability of microorganisms to ferment carbohydrates and the types of products formed are very useful in identificat ...
Biochemistry Biochemistry is the science concerned the chemical
... The aim of the class: the determination of the initial velocity and Michaelis constant in reaction catalysed by saccharase Theoretical basis: the enzyme-catalyzed reaction, the definitions of initial velocity, maximal velocity and Michaelis constant, the Michaelis-Menten equation, the standard units ...
... The aim of the class: the determination of the initial velocity and Michaelis constant in reaction catalysed by saccharase Theoretical basis: the enzyme-catalyzed reaction, the definitions of initial velocity, maximal velocity and Michaelis constant, the Michaelis-Menten equation, the standard units ...
Enzyme - Rubin Gulaboski
... Different versions of the same enzyme (often made by alternative splicing) are called isoenzymes or isozymes General classes of enzymes ...
... Different versions of the same enzyme (often made by alternative splicing) are called isoenzymes or isozymes General classes of enzymes ...
Biology Unit - The Connected Hub
... Clearly, not all of the ___’s energy that becomes stored in the _______ will end up in the fox. Only around ______ is passed on to the next stage in each food chain. Energy is lost at each stage because of a number of reasons: 1) Each organism has to ____, keep warm etc 2) Energy is lost through fae ...
... Clearly, not all of the ___’s energy that becomes stored in the _______ will end up in the fox. Only around ______ is passed on to the next stage in each food chain. Energy is lost at each stage because of a number of reasons: 1) Each organism has to ____, keep warm etc 2) Energy is lost through fae ...
Oxidation of C`4-labeled Carbohydrate
... high respiration, and a respiratory quotient which is intermediate between 0.7 and 1.0 are some of the biochemical properties which are noted quite constantly in a high proportion of ma lignant tumors (6). In his classical studies of tumor metabolism Warburg (53) placed great emphasis upon the relat ...
... high respiration, and a respiratory quotient which is intermediate between 0.7 and 1.0 are some of the biochemical properties which are noted quite constantly in a high proportion of ma lignant tumors (6). In his classical studies of tumor metabolism Warburg (53) placed great emphasis upon the relat ...
Additional data file
... Aromatic aminotransferase, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism Putative protein of unknown function with similarity to aldo/keto reductases; YMR041C is not an essential gene Aromatic aminotransferase, expression is regulated by general control of amino acid ...
... Aromatic aminotransferase, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism Putative protein of unknown function with similarity to aldo/keto reductases; YMR041C is not an essential gene Aromatic aminotransferase, expression is regulated by general control of amino acid ...
igcse_enzyme_ppt
... Cheese is made by adding an enzyme called rennet after bacteria have produced lactic acid ...
... Cheese is made by adding an enzyme called rennet after bacteria have produced lactic acid ...
Chemical constituents
... Nucleotides and nucleic acids - The basic components of nucleotides. Mononucleotides : ATP (adenosine triphosphate) as an energy carrier. Dinucleotides : NAD (nicotinamide adenine dinucleotide) as a coenzyme. Polynucleotides : RNA (ribonucleic acid) and DNA (deoxyribonucleic acid). Inorganic compone ...
... Nucleotides and nucleic acids - The basic components of nucleotides. Mononucleotides : ATP (adenosine triphosphate) as an energy carrier. Dinucleotides : NAD (nicotinamide adenine dinucleotide) as a coenzyme. Polynucleotides : RNA (ribonucleic acid) and DNA (deoxyribonucleic acid). Inorganic compone ...
Targeting Cancer Metabolism
... mutations and alterations in several metabolism-related enzymes—isocitrate dehydrogenase 1 (IDH1), isocitrate dehydrogenase 2 (IDH2), succinate dehydrogenase (SDH), fumarate hydratase (FH), and pyruvate kinase M2 (PKM2)—has renewed interest in cancer metabolism and renewed hope of taking therapeutic ...
... mutations and alterations in several metabolism-related enzymes—isocitrate dehydrogenase 1 (IDH1), isocitrate dehydrogenase 2 (IDH2), succinate dehydrogenase (SDH), fumarate hydratase (FH), and pyruvate kinase M2 (PKM2)—has renewed interest in cancer metabolism and renewed hope of taking therapeutic ...
Acid/Base: Salicylate Toxicity
... An acidic pH promotes the movement of salicylate into the tissues ...
... An acidic pH promotes the movement of salicylate into the tissues ...
Short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency
... from fatty acids to glucose as fuel. It has been proposed that, as in other tissues, this occurs in the β-cell through conversion of glucose, via pyruvate carboxylase, oxaloacetate, citrate and acetyl-CoA, to malonyl-CoA which, by inhibiting CPT I (outer membrane carnitine palmitoyltransferase I), b ...
... from fatty acids to glucose as fuel. It has been proposed that, as in other tissues, this occurs in the β-cell through conversion of glucose, via pyruvate carboxylase, oxaloacetate, citrate and acetyl-CoA, to malonyl-CoA which, by inhibiting CPT I (outer membrane carnitine palmitoyltransferase I), b ...
F214: Communication, Homeostasis and Energy
... ethanol into ethanal (acetaldehyde) • The enzyme aldehyde dehydrogenase then converts ethanal (acetaldehyde) into ethanoate (acetate) • This can then be combined with coenzyme A to form Acetyl Coenzyme A, which then enters the Kreb’s cycle and be metabolised to produce ATP • Ethanol is therefore a s ...
... ethanol into ethanal (acetaldehyde) • The enzyme aldehyde dehydrogenase then converts ethanal (acetaldehyde) into ethanoate (acetate) • This can then be combined with coenzyme A to form Acetyl Coenzyme A, which then enters the Kreb’s cycle and be metabolised to produce ATP • Ethanol is therefore a s ...
Biological Oxidation
... Energy from Cytosolic NADH In contrast to oxidation of mitochondrial NADH, cytosolic NADH when oxidized via the electron transport system gives rise to 2 equivalents of ATP if it is oxidized by the glycerol phosphate shuttle and 3 ATPs if it proceeds via the malate aspartate shuttle. The glycerol p ...
... Energy from Cytosolic NADH In contrast to oxidation of mitochondrial NADH, cytosolic NADH when oxidized via the electron transport system gives rise to 2 equivalents of ATP if it is oxidized by the glycerol phosphate shuttle and 3 ATPs if it proceeds via the malate aspartate shuttle. The glycerol p ...
23.1 The Citric Acid Cycle
... Karen C. Timberlake General, Organic, and Biological Chemistry: Structures of Life, 5/e Karen C. Timberlake ...
... Karen C. Timberlake General, Organic, and Biological Chemistry: Structures of Life, 5/e Karen C. Timberlake ...
Functions of the liver Assessment and interpretation of liver function
... • Most abundant protein • Normal plasma conc- 3 - 5 g% • Daily production -12-15 g/d ...
... • Most abundant protein • Normal plasma conc- 3 - 5 g% • Daily production -12-15 g/d ...
Cholesterol Synthesis Regulation of cholesterol synthesis pathway
... Fatty acids absorbed into blood through stomach wall stimulate gall bladder to contract, releasing bile. ...
... Fatty acids absorbed into blood through stomach wall stimulate gall bladder to contract, releasing bile. ...
Executive Stress Formula
... Wobenzym N has proven to be a safe and useful product. In the human body, hundreds of chemical reactions occur during the course of normal metabolic processes. Many chemical reactions require significant energy in order to take place, and therefore need a catalyst to allow the reaction to proceed. T ...
... Wobenzym N has proven to be a safe and useful product. In the human body, hundreds of chemical reactions occur during the course of normal metabolic processes. Many chemical reactions require significant energy in order to take place, and therefore need a catalyst to allow the reaction to proceed. T ...
1 CHRONIC LIVER DISEASES DERANGEMENTS OF HEPATIC
... The liver also produces a wide variety of secretory glycoproteins. Some of them are very important for the clinicians for example ceruloplasmin, alpha antitrypsin and most other alpha and beta globulins. While the site of albumin catabolism is uncertain, the removal of terminal sialic acid residues ...
... The liver also produces a wide variety of secretory glycoproteins. Some of them are very important for the clinicians for example ceruloplasmin, alpha antitrypsin and most other alpha and beta globulins. While the site of albumin catabolism is uncertain, the removal of terminal sialic acid residues ...
Slide 1
... a point is reached where increase in substrates concentration does not affect the reaction rate because of • A.Enzymes get denatured at higher substrate conc. • All the active sites on enzyme molecule are occupied. ...
... a point is reached where increase in substrates concentration does not affect the reaction rate because of • A.Enzymes get denatured at higher substrate conc. • All the active sites on enzyme molecule are occupied. ...
T-cell metabolism in autoimmune disease
... In this context, it is important to consider kinetics of cellular responses, in that glucose and glutamine are rapidly available and are easy to metabolize. Fatty acids may be more important for long-term energy storage. As signaling molecules and membrane building blocks, they play a compulsory rol ...
... In this context, it is important to consider kinetics of cellular responses, in that glucose and glutamine are rapidly available and are easy to metabolize. Fatty acids may be more important for long-term energy storage. As signaling molecules and membrane building blocks, they play a compulsory rol ...
Glycolysis
Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+. The free energy released in this process is used to form the high-energy compounds ATP (adenosine triphosphate) and NADH (reduced nicotinamide adenine dinucleotide).Glycolysis is a determined sequence of ten enzyme-catalyzed reactions. The intermediates provide entry points to glycolysis. For example, most monosaccharides, such as fructose and galactose, can be converted to one of these intermediates. The intermediates may also be directly useful. For example, the intermediate dihydroxyacetone phosphate (DHAP) is a source of the glycerol that combines with fatty acids to form fat.Glycolysis is an oxygen independent metabolic pathway, meaning that it does not use molecular oxygen (i.e. atmospheric oxygen) for any of its reactions. However the products of glycolysis (pyruvate and NADH + H+) are sometimes disposed of using atmospheric oxygen. When molecular oxygen is used in the disposal of the products of glycolysis the process is usually referred to as aerobic, whereas if the disposal uses no oxygen the process is said to be anaerobic. Thus, glycolysis occurs, with variations, in nearly all organisms, both aerobic and anaerobic. The wide occurrence of glycolysis indicates that it is one of the most ancient metabolic pathways. Indeed, the reactions that constitute glycolysis and its parallel pathway, the pentose phosphate pathway, occur metal-catalyzed under the oxygen-free conditions of the Archean oceans, also in the absence of enzymes. Glycolysis could thus have originated from chemical constraints of the prebiotic world.Glycolysis occurs in most organisms in the cytosol of the cell. The most common type of glycolysis is the Embden–Meyerhof–Parnas (EMP pathway), which was discovered by Gustav Embden, Otto Meyerhof, and Jakub Karol Parnas. Glycolysis also refers to other pathways, such as the Entner–Doudoroff pathway and various heterofermentative and homofermentative pathways. However, the discussion here will be limited to the Embden–Meyerhof–Parnas pathway.The entire glycolysis pathway can be separated into two phases: The Preparatory Phase – in which ATP is consumed and is hence also known as the investment phase The Pay Off Phase – in which ATP is produced.↑ ↑ 2.0 2.1 ↑ ↑ ↑ ↑ ↑ ↑