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For lecture notes click here
For lecture notes click here

...  important as an energy reserve, because they can provide large amounts of ATP  They are insoluble, so lipids can be stored in compact droplets in the cytosol (This storage method saves space, but when the lipid droplets are large, it is difficult for water-soluble enzymes to get at them. Lipid re ...
exam1ans_2007
exam1ans_2007

... stabilizing/destabilizing the folded form of the protein relative to the other three choices. Sample answer: Electrostatic effects involve attraction and repulsion of charged groups in proteins (e.g. Asp and Lys). This is largely an enthalpic (ΔH) effect. It has very little influence on stabilizing ...
lec4-5-biosynthesis_specificity
lec4-5-biosynthesis_specificity

... • a good 3-D structure should be available • It is often based on molecular graphics or more advanced molecular modeling (structure-based computational design techniques) • Such models place an emphasis on enthalpic interactions and omit entropic contributions ...
Chapter 1 Non-Canonical Amino Acids in Protein Engineering
Chapter 1 Non-Canonical Amino Acids in Protein Engineering

c - SchoolRack
c - SchoolRack

... molecule. (Do not confuse this functional group with the hydroxide ion, OH–.) Figure 4.10 ...
SOURCES OF OUR OBJECTIONS Series A
SOURCES OF OUR OBJECTIONS Series A

... Proteins are chains of amino acid molecules connected by peptide bonds. There are many types of proteins and each has its own amino acid sequence (typically containing hundreds of amino acids). There are 22 different amino acids that can be combined to form protein chains. There are 9 amino acids th ...
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Slide 1

... In unsaturated fatty acids, there are two ways the pieces of the hydrocarbon tail can be arranged around a C=C double bond. In cis bonds, the two pieces of the carbon chain on either side of the double bond are either both “up” or both “down,” such that both are on the same side of the molecule. In ...
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3 .Micronutrients GIT

LEARNING OBJECTIVES Vitamin B12, Folic Acid and B6 • To
LEARNING OBJECTIVES Vitamin B12, Folic Acid and B6 • To

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Biological importance of Uronic Acid Pathway
Biological importance of Uronic Acid Pathway

... It is ironic that antimalarial drugs can cause illness through the same biochemical mechanism that provides resistance to malaria. Divicine also acts as an antimalarial drug, and ingestion of fava beans may protect against malaria. ...
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Nitrogen Assimilation 1. Introduction and Overview Importance of

...   -­‐  transcription  is  activated  by  NO3-­‐,  NH4+,  light  (both  enzymes)     -­‐  large  amount  present  -­‐  rapid  assimilation  of  NH4+  (toxic)     -­‐  connected  to  photorespiration  (=  metabolic  reactions  to     ...
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2009/05/21 Lecture

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Protein Biosynthesis at Three Levels of Modifications

... determination in protein structure studies. 2. A spin-labeled nonnatural amino acid, containing nitroxyl 1-oxyl2,2,5,5-tetramethylpyrroline, was site-specifically incorporated into a T4 lysozyme using in vitro translation to yield a protein that had an electron ...
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Protein

... carboxyl group, plus the amino acids also contain an amine group. – Amine group = composed of two atoms of hydrogen and one atom of nitrogen. – (Look on page 258, figure 17-1, both carboxyl group and the amine group are attached to a central carbon.) – With four bonds needed and one is left open, th ...
Tricarboxylic Acid Cycle
Tricarboxylic Acid Cycle

... FAcarbon skeleton : CO2 & H2O provides energy (ATP) occurs in mitochondriain close proximity to reactions of electron transport  AerobicO2 required as the final electron acceptor  Participates in synthetic rx/: formation of glucose from carbon skeleton of some AA  Intermediates of the TCA cy ...
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No Slide Title

...  E3 activation is observed in 90% of cervical carcinoma.  NF-kB (transcription factor) initiates the expression of a number of the genes that take part in this process.  NF-kB normally remains inactivated by binding to an inhibitory protein, I-kB. ...
Chapter 12
Chapter 12

... Peptide bond An amide functional group that forms when the carboxylic acid group on one amino acid reacts with the amine group of another amino acid. Peptide A substance that contains two or more amino acids linked together by peptide bonds. ...
GraphPAC: Graph Theoretical Identification of Mutated Amino Acid
GraphPAC: Graph Theoretical Identification of Mutated Amino Acid

... space by solving the Traveling Salesman Problem (TSP) heuristically via the TSP package [Hahsler and Hornik, 2011]. Once a hueristic solution to the TSP has been found, the protein is reorganized to a one-dimensional space by walking the path from the first amino acid to the last. The Nonrandom Muta ...
Proteins and Enzymes
Proteins and Enzymes

... lactose sugars It’s a disaccharide ...
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Methods of industrial production 1

... • Bacteria do not normally excrete amino acids in significant amounts because regulatory mechanisms control amino acid synthesis in an economical way so that the needs of the cell (for protein synthesis) are exactly matched by the synthetic processes. • There are no surplus amino acids and only a sm ...
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1X Equilibration/Wash Buffer (pH 7.0)

Chapter 3 Powerpoint - Trimble County Schools
Chapter 3 Powerpoint - Trimble County Schools

... – They can be sold as prescription drugs and used to treat certain diseases – They may also be abused with serious consequences, such as liver damage that can lead to cancer ...
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Lecture 27

... 3: Fe(IV)=O2- reacts with Phe to form an epoxide across the 3,4 bond. 4: epoxide opening to form carbocation at C3 ...
The Organic Chemistry of Amino Acids, Peptides, and Proteins
The Organic Chemistry of Amino Acids, Peptides, and Proteins

... The next step is to determine the number and kinds of amino acids in the peptide or protein by hydrolysis of all the amide bonds and then analysis of the mixture. ...
Chemical Biology - Chem 370 (3 credits)
Chemical Biology - Chem 370 (3 credits)

... 2. Water. a. Polar covalent bonds, hybridization, and the structure of water and water clusters. b. Buffers, ions in solution, micelles, and membranes. c. Bonding: Covalent, ionic, and hydrophobic effects. d. Water as a nucleophile. e. Water as an acid or base: organic functional groups in biologica ...
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Peptide synthesis

In organic chemistry, peptide synthesis is the production of peptides, which are organic compounds in which multiple amino acids are linked via amide bonds, also known as peptide bonds. The biological process of producing long peptides (proteins) is known as protein biosynthesis.
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