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Quiz Next Tuesday (09/18) - Chemistry at Winthrop University
Quiz Next Tuesday (09/18) - Chemistry at Winthrop University

... can react with the resulting loss of a water molecule to form a covalent amide bond. ...
Lab 1 activity, AMINO ACIDS - Cal State LA
Lab 1 activity, AMINO ACIDS - Cal State LA

... Planar peptide groups in a protein • Rotation around C-N bond is restricted due to 40% double-bond nature of the resonance hybrid form • Peptide groups (blue planes) are therefore planar; restrict conformations possible in protein chains ...
- Peptide Machines, Inc.
- Peptide Machines, Inc.

... clogged lines, and overfills so typical of other instruments.  The use of stock solutions of AA's eliminates the need for pre-fill cartridges or barcoding. ...
J. Indian. Chem. Soc. 1999, 76, 631-639
J. Indian. Chem. Soc. 1999, 76, 631-639

... J. Indian. Chem. Soc. 1999, 76, 631-639. N-protected amino acid allylic esters can easily be deprotonated by LDA at -78 °C and transmetallated by addition of metal salts. Chelated metal enolates, which undergo Claisen rearrangements upon warming up to room temperature, giving rise to unsaturated ami ...
FMOC The solid phase peptide synthesis (SPPS) was first
FMOC The solid phase peptide synthesis (SPPS) was first

... temporary acid labile protecting group, t-butoxycarbonyl (tBoc), on the a-amino position, and by a more acid stable benzyl type protecting group on the functionality of the side chain. The t-Boc group is deprotected by trifluoroacetic acid (TFA) followed by the neutralization and washing steps, and ...
Chapter 26: Biomolecules: Amino Acids Peptides and Proteins
Chapter 26: Biomolecules: Amino Acids Peptides and Proteins

... Peptide synthesis requires that different amide bonds must be formed in a desired sequence The growing chain is protected at the carboxyl terminal and added amino acids are N-protected After peptide bond formation, N-protection is removed ...
A1980JX53900001
A1980JX53900001

... benzyloxycarbonyl amino acids, suggested that this could be a general method for the synthesis of any long peptide chain. This view was expressed also in the title of our paper The repetitiveness of the operation seemed to lend itself to mechanization and automation,2 and the stepwise strategy indee ...
Scale - Netherlands Cancer Institute
Scale - Netherlands Cancer Institute

... Request for PEPTIDE SYNTHESIS 2014 (intern) Henk Hilkmann, lab B6.001, tel: 020-5121974, [email protected] Dris El Atmioui, lab B6.001, tel: 020-5121974, [email protected] ...
Artificial Small-Molecule Peptide Synthesizer
Artificial Small-Molecule Peptide Synthesizer

TABLE 8–6 Some Reagents Commonly Used to Cleave Peptide
TABLE 8–6 Some Reagents Commonly Used to Cleave Peptide

Chapter Twenty-Seven: Amino Acids
Chapter Twenty-Seven: Amino Acids

... o Rinse solid support o Add second N-protected amino acid via C-terminus ...
Amino Acid Single and Three letter codes Name of Amino Acid
Amino Acid Single and Three letter codes Name of Amino Acid

... Custom Peptides - Amino Acid Single and Three letter codes ...
The Synthesis and Expression of Peptide CbnY Thomas Doerksen
The Synthesis and Expression of Peptide CbnY Thomas Doerksen

... Bacteriocins are small antimicrobial peptides produced by bacteria, and have great potential in the food industry as an alternative to antibiotics. The two-component bacteriocins, produced by various strains of lactic acid bacteria, display optimal activity when complexed together. A bacteriocin, Cb ...
CHAP Twenty-Five - Foothill College
CHAP Twenty-Five - Foothill College

... D) Separation and Identification of aa fragments via Gel electrophoresis, Ionexchange chromatography, and Mass Spectrometry 4) Peptide Synthesis A) Traditional solution synthesis i) Role of DCC ii) N-protecting groups: BOC and FMOC iii) C-protecting groups: PhCH2OH and 1° ROH B) Merrifield Solid Pha ...
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Peptide synthesis

In organic chemistry, peptide synthesis is the production of peptides, which are organic compounds in which multiple amino acids are linked via amide bonds, also known as peptide bonds. The biological process of producing long peptides (proteins) is known as protein biosynthesis.
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