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phosphorus - Sacred Heart Academy
phosphorus - Sacred Heart Academy

... complementary bases • Replication occurs in the 5‘ to 3‘ direction (lead strand and lag strand); bases can only be added to the 3’ end of the growing DNA molecule • Other enzymes correct errors, remove primers, seal “nicks” in the backbone ...


... the genome. Since the last century the replicon model has been proposed in order to explain the general mechanism of genome duplication in bacteria. Later work in yeast lead to identifying proteins and dna sequences that participate in the initiation of replication in a similar fashion to what has b ...
Book 11.5 HB Questions
Book 11.5 HB Questions

... 5. The process of joining exons together to form an mRNA molecule is called _________________________. 6. During transcription, the _________________________ between base pairs are broken. 7. A mutation will cause the cell to make an incomplete polypeptide if the mutation results in a(an) __________ ...
MS Word File
MS Word File

... Polymerase has ability to recognize a mismatch and remove last base Can continue down strand, but slowly Mutation and DNA Repair Mutation-change in DNA sequence Can happen naturally during replication when mismatch is not recognized 1 in 100,000 bases incorrectly added 99% of these are corrected by ...
DNA Replication: Synthesis of Lagging Strand
DNA Replication: Synthesis of Lagging Strand

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1chap10guidedreading
1chap10guidedreading

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Micro Quiz #3R Stu F2011 - the Biology Scholars Program Wiki
Micro Quiz #3R Stu F2011 - the Biology Scholars Program Wiki

... 4. AT-rich DNA strands will denature (separate) at a(n): A. Higher temperature than GC-rich DNA B. Identical temperature as GC-rich DNA C. Similar temperature as GC-rich DNA, with minor variations D. Lower temperature than GC-rich DNA E. Temperature dependent upon whether it is from a prokaryote or ...
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... Linear chromosomes (like most eukaryotes) ...
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Exam Review 2B -- Rodermel
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... Joins Okazaki fragments by sealing breaks in the sugar-phosphate backbone of newly synthesized DNA Attach to single-stranded DNA and prevent secondary structures from forming Unwinds DNA at replication fork ...
AP Bio Ch 17 The Molecular Basis of Disease This chapter is only
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DNA polymerase I
DNA polymerase I

... Overview of DNA Synthesis DNA polymerases synthesize new strands in 5’ to 3’ direction. Primase makes RNA primer. Lagging strand DNA consists of Okazaki fragments. In E. coli, pol I fills in gaps in the lagging strand and removes RNA primer. Fragments are joined by DNA ...
Dna rEPLICATION - Manning`s Science
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... The lagging strand takes longer to replicate than the leading strand because it involves more steps and is not continuous replication. ...
NAME CH. 8 HONORS STUDY GUIDE SCIENTISTS: Hershey
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... 12. What is the job of the mRNA? 13. What is the job of rRNA? 14. What is the job of tRNA? 15. What RNA molecules are involved in protein synthesis? 16. Which RNA molecule functions as the blueprint of the genetic code? 17. Where is mRNA edited? Explain what is removed & what is put back together. 1 ...
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Code DNA!
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molecular genetics unit review
molecular genetics unit review

... c) Watson and Crick d) Meselson and Stahl Describe the structure of DNA. Include terms like anti-parallel, nucleotide (phosphate, sugar, nitrogenous base), 3’ and 5’ end, hydrogen bonds, complementary base pairing and phosphodiester bonds in your description. Provide the functions of the following e ...
CHAPTER 6
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Chapter 16 Reading Questions What were the 2 candidates for the

... 16. Explain how tRNA helps to build amino acids. Use codon, mRNA, anticodon and ribosome in your answer. ...
Molecular Biology Chapter 10: DNA – Replication and Protein
Molecular Biology Chapter 10: DNA – Replication and Protein

... 10.3 DNA as a Double-Helix 1. Describe the structure of DNA. What holds the two strands together? 10.4 and 10.5 DNA Replication 1. Describe in brief how DNA is replicated. How does complementary base pairing make possible the replication of DNA? 2. Explain in detail how DNA is replicated, starting f ...
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Replisome



The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized. The net result is formation of two new double stranded DNA sequences that are exact copies of the original double stranded DNA sequence.In terms of structure, the replisome is composed of two replicative polymerase complexes, one of which synthesizes the leading strand, while the other synthesizes the lagging strand. The replisome is composed of a number of proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase I, RNAse H, and ligase.
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