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REVIEW OF MOLECULAR GENETICS - Pascack Valley Regional
REVIEW OF MOLECULAR GENETICS - Pascack Valley Regional

... DNA library - a random collection of DNA fragments from an organism cloned into a vector Ideally contains at least one copy of every DNA sequence. Easily maintained in the laboratory Can be manipulated in various ways to facilitate the isolation of a DNA fragment of interest to a scientist. Num ...
What is a genome?
What is a genome?

... •  Process by which DNA copies  itself before cell division  •  DNA Molecule is “unzipped”  between bases by enzymes  called helicases  •  DNA polymerase enzymes  copy each strand to make 2  new iden9cal DNA molecules  •  DNA ligase joins fragments of  DNA together  •  See DNA Replica9on Tutorial  f ...
Seeking an Increasingly Explicit Definition of Heredity
Seeking an Increasingly Explicit Definition of Heredity

... Irradiated the red bread mold, Neurospora, and proved that the gene produces its effect by regulating particular enzymes. One gene/one ...
Chapter 9 and 10 - Grafton School District
Chapter 9 and 10 - Grafton School District

... – Single stranded – Nitrogen bases: ...
Station 7 - Components of DNA
Station 7 - Components of DNA

... • Nucleotides are made up of a sugar, a phosphate group, a base, held together by hydrogen bonds. • The amounts of adenine and thymine found in DNA are equal. • DNA molecules are made up of a double helix containing two strands. • Weak hydrogen bonds hold the DNA molecule together. • DNA is found in ...
Chapter 20 Notes: DNA Technology
Chapter 20 Notes: DNA Technology

... from test tubes back into cells ...
Midterm Review Paper
Midterm Review Paper

... 10. What are the sex chromosomes of a male? Female? 11. What sex chromosomes does a father give to his child? 12. What sex chromosomes does a mother give to her child? 13. What is genotype? 14. What is phenotype? 15. Understand the different blood types. 16. Most sex linked genes are located where? ...
Warm Up - lifewithlloyd
Warm Up - lifewithlloyd

... • Before any cell can make a copy of itself, all the DNA must be copied! • This is called DNA replication. ...
AP Biology, Chapter 16 The Molecular Basis of Inheritance Life`s
AP Biology, Chapter 16 The Molecular Basis of Inheritance Life`s

... 6. Describe the process of DNA replication. Note the structure of the many origins of replication and replication forks and explain the role of DNA polymerase. DNA sequences where replication begins = origins of replication Appear as a bubble in EM Origin is essential for DNA to be copied Replicatio ...
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DNA Helix Strand

... the gene for brown hair or the gene for blue eyes. ...
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DNA Restriction and mechanism

... • The mammalian enzymes methylate the cytosine in mainly CG sequences to 5-methylcytosine (5-meC), but they do it efficiently only if the cytosine in the opposite strand already bears a methyl residue. The result is that CG sequences that are methylated perpetuate their methylated state following DN ...
THE CELLULAR AND MOLECULAR BASIS OF INHERITANCE
THE CELLULAR AND MOLECULAR BASIS OF INHERITANCE

... into a right handed helix, called the double helix. • Each strand is a polymer of repeating units called nucleotides. ...
Gene Technology
Gene Technology

... Identify the 3.2 billion base pairs of DNA that makes up humans  Large portion of DNA does not code, only 1% to 1.5% make proteins  Only 30,000 to 40,000 genes (much less than expected) ...
DNA - Paxon Biology
DNA - Paxon Biology

... DNA is a double helix, however, only 1 of these strands is transcribed. The strand that is transcribed is called the template strand. The other strand is NOT transcribed and is called the non-template strand; it serves as a template for making a new strand during replication. An mRNA will be complem ...
Transcription
Transcription

... making RNA, then unwinds/splits DNA into 2 separate strands. 2. One strand – of DNA acts as a template for making mRNA. 3. RNA Polymerase – moves along the DNA and pairs each base with a complementary RNA nucleotide 4. Continues – until enzyme reaches a terminator (stop signal). 5. RNA Polymerase – ...
DNA
DNA

... • The rungs (part you’d step on) are 2 of the nitrogen bases • Each rung is one purine paired with one pyrimidine – always C-G and A-T ...
Higher Biology Unit 1: DNA and the Genome 5
Higher Biology Unit 1: DNA and the Genome 5

... tool for estimating the dates of lineage-splitting events. For example, imagine that a length of DNA found in two species differs by four bases (as shown below) and we know that this entire length of DNA changes at a rate of approximately one base per 25 million years. That means that the two DNA ve ...
BY2208 SF Genetics Central Dogma McConnell_1.1
BY2208 SF Genetics Central Dogma McConnell_1.1

... Genes must contain information! Genes must replicate! ...
DNA and RNA - Kania´s Science Page
DNA and RNA - Kania´s Science Page

... • To analyze chromosomes, cell biologists PHOTOGRAPH cells in MITOSIS. • Next, they cut out the chromosomes and group them in pairs. • This is called a KARYOTYPE ...
Genetic Engineering and The Human Genome
Genetic Engineering and The Human Genome

... • Karyotypes, pictures of chromosomes, can be used to study our chromosomes. ...
DNA Replication
DNA Replication

... each new strand is half original strand and half newly made strand ...
DNA Structure and Replication
DNA Structure and Replication

... 3. How long does it take for your cells to replicate your DNA? 4. When DNA is replicated during the cell cycle? 5. What is the average rate of DNA replication? 6. How does DNA speed up the process of replication? 7. How are the bases of the nucleotides held together? DNA REPLICATION http://www.hhmi. ...
DNA and Genes - Mecca Hosting Client Sites on rhode
DNA and Genes - Mecca Hosting Client Sites on rhode

... 7. Each set of three nitrogen basesthat .E ...
Modeling Mutations Activity
Modeling Mutations Activity

DNA - Wsfcs
DNA - Wsfcs

...  Adenine pairs with Thymine Guanine pairs with Cytosine  The nitrogen bases are held together by hydrogen bonds.  Due to the base pairing the two strands are complementary to each other ...
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Replisome



The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized. The net result is formation of two new double stranded DNA sequences that are exact copies of the original double stranded DNA sequence.In terms of structure, the replisome is composed of two replicative polymerase complexes, one of which synthesizes the leading strand, while the other synthesizes the lagging strand. The replisome is composed of a number of proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase I, RNAse H, and ligase.
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