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1. Biochemistry: The Chemistry of Life
1. Biochemistry: The Chemistry of Life

... The DNA molecule consists of two strands twisted around each other into a double helix resembling a ladder twisted around its long axis. The outside, or uprights, of the ladder are formed by the two sugar-phosphate backbones. The rungs of the ladder are composed of pairs of nitrogen bases, one exten ...
AP Biology Discussion Notes
AP Biology Discussion Notes

... • Chargaff’s research determined that in DNA there were always equal parts • Humans Adenine = 30% • Humans Thymine = ? • Humans Guanine = ? • Humans Cytosine = ? ...
DNA (Deoxyribonucleic Acid)
DNA (Deoxyribonucleic Acid)

... living organisms. ...
Transposons_&_DNA_Mutations
Transposons_&_DNA_Mutations

... Inheritable change in DNA sequence Relatively rare Generally occur during DNA replication or repair – May also occur in response to mobile DNA elements Transposons and viruses ...
DNA: deoxyribonucleic acid
DNA: deoxyribonucleic acid

... DNA: deoxyribonucleic acid DNA history, structure, replication, and gene expression (transcription, translation, protein synthesis) ...
HONORS BIOLOGY FINAL EXAM REVIEW PACKET AND FORMAT
HONORS BIOLOGY FINAL EXAM REVIEW PACKET AND FORMAT

... THREE NUCLEOTIDES CODE FOR AN AMINO ACID (CODON) RIBOSOMES PROVIDE A PLACE FOR THE mRNA TO ATTACH RNA POLYMERASE IS AN ENZYME THAT UNZIPS THE DNA DOUBLE HELIX AND PUTS THE mRNA NUCLEOTIDES IN SEQUENCE THE DNA SEQUENCE TTTCCGGCA BECOMES THE RNA SEQUENCE AAAGGCCGU THE SEQUENCE OF PROTEIN SYNTHESIS IS ...
Cell Division
Cell Division

... The Genetic Code: DNA – code for all life – in all cells DNA coils to form Chromosomes A Gene is a section of DNA Genetic info is encoded in sequence of base triplets, called codons ...
(51509) - OpenWetWare
(51509) - OpenWetWare

Sos response in E. coli
Sos response in E. coli

Nucleotide
Nucleotide

CHAPTER 14: DNA: THE GENETIC MATERIAL
CHAPTER 14: DNA: THE GENETIC MATERIAL

... b. Is a dimer with two similar multisubunit complexes 3. Variety of proteins have unique duties a. Large α subunit catalyses 5’ to 3’ addition of nucleotides b. Smaller ε subunit proofreads 3’ to 5’ strand for mistakes c. Ring-shaped β2 dimer subunit clamps polymerase III complex around DNA helix d. ...
Cloning
Cloning

... Generally do not kill host cell Relatively easy to purify Can be made small ...
Transposition and transposable elements
Transposition and transposable elements

... usually with sister chromosome, restoring transposon at original site sometimes end healed without transposon, can also be associated with deletion at excision site ...
Does your DNA define you Ans
Does your DNA define you Ans

... DNA itself or to the proteins DNA is associated with. Epigenetics is the study of these reactions and the factors that influence them. Epigenetic changes are caused by environmental factors such as diet, pollution, lifestyle such as smoking and alcohol, radiation and exposure to chemicals. These cha ...
The Connection between Genes and Proteins
The Connection between Genes and Proteins

... Explain how RNA polymerase recognizes where transcription should begin. Describe the promoter, the terminator, and the transcription unit. ...
Genetics mini-quiz
Genetics mini-quiz

... e. frameshift 9. A mutation that results in substituting one amino acid for another is called: a. Silent mutation b. Missense change c. Nonsense change d. Indel e. frameshift 10. A mutation that does not affect the amino acid sequence is called: a. Silent mutation b. Missense change c. Nonsense chan ...
1.3. Identity: Molecules and Cells Study Guide (Fisher)
1.3. Identity: Molecules and Cells Study Guide (Fisher)

Lecture #7 Date - clevengerscience
Lecture #7 Date - clevengerscience

... Genes are not expressed all the time. Some genes are usually on, but can be turned off by repressors when they are not needed. Some genes are usually off, but they can be turned on by enhancers when they are needed. ...
dna & rna - Department of Electrical Engineering and Computing
dna & rna - Department of Electrical Engineering and Computing

DNA replication - Cloudfront.net
DNA replication - Cloudfront.net

Human DNA Dance - University of Wisconsin Biotechnology Center
Human DNA Dance - University of Wisconsin Biotechnology Center

... You can show how DNA can melt into two single strands by asking the two lines to release their handshakes and take one step to the left, while keeping their right hands in the C, T, G or A form. You can show how two complementary single strands of DNA can anneal (come together) by then having the tw ...
Study Guide MBMB 451A Fall 2002
Study Guide MBMB 451A Fall 2002

... 3. What are the properties of different protein helical structures and how are they named? What is an alpha helix? 4. What are the properties of various beta sheets and what are the forces that stabilize them and alpha helices? 5. What is the structure of collagen? How is a coiled-coil and a random ...
1.3. Identity: Molecules and Cells Study Guide
1.3. Identity: Molecules and Cells Study Guide

... electrode. When the electricity is started, they move toward the positive electrode. Smaller bits are lighter and travel faster, so the bits get separated by size. This makes it possible to tell ...
LNUC IV.A - UTK-EECS
LNUC IV.A - UTK-EECS

... ¶1. Denaturation: causes DNA to unwind and separate into its two strands. This occurs by breaking the H-bonds between the bases. ¶2. Thermal denaturing is most common (about 95 C), but there are also chemical denaturing agents. A.3.b ...
Worksheet 15.3 Applications of Genetic Engineering
Worksheet 15.3 Applications of Genetic Engineering

... Examples include vitamin-rich rice, human proteins made in animals, animal models of human disease (for research), and bacteria that produce human insulin. Gene therapy is the process of changing a gene to treat a disorder. However, gene therapy is still an experimental and high-risk technique. Gene ...
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Replisome



The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized. The net result is formation of two new double stranded DNA sequences that are exact copies of the original double stranded DNA sequence.In terms of structure, the replisome is composed of two replicative polymerase complexes, one of which synthesizes the leading strand, while the other synthesizes the lagging strand. The replisome is composed of a number of proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase I, RNAse H, and ligase.
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