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From Gene to Protein
From Gene to Protein

...  Demonstrates redundancy, ...
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Niemann Pick LAB

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Genetic Control of Cell Function and Inheritance

... • Long, double-stranded helical structure composed of nucleotides, which consist of phosphoric acid, deoxyribose, and one of four nitrogenous bases (T,C,A or G) • Spiral staircase with paired bases representing the steps • Nitrogenous bases carry the genetic information ...
Mantelstudium ``Biomedizinische Wissenschaften``
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... dideoxynucleotides as chain terminators to produce a ladder of molecules generated by polymerase extension of a primer. RNA Sequencing: A set of four RNases that cleave 3‫׳‬to specific nucleotides to produce a ladder of fragments from endlabeled RNA, using polacrylamide gel electrophoresis (PAGE) an ...
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Molecular Basis

... Returning to the original problem at the replication fork, the leading strand requires the formation of only a single primer as the replication fork continues to separate. ...
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... in the order of the basepairs. Mutations may affect a single basepair, (point mutation) where they may change the sequence in an RNA or protein, or not (silent mutation). During protein synthesis, bases are read 3 at a time (codon); when the first base is read, the “reading frame” is established. If ...
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Nucleus - Maryville University
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... • Steps of replication process – DNA helicase opens short segment of helix • replication fork is point of separation of 2 strands ...
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Genetics (4) - HCC Learning Web

... • Steps of replication process – DNA helicase opens short segment of helix • replication fork is point of separation of 2 strands ...
DNA
DNA

< 1 ... 381 382 383 384 385 386 387 388 389 ... 657 >

Replisome



The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized. The net result is formation of two new double stranded DNA sequences that are exact copies of the original double stranded DNA sequence.In terms of structure, the replisome is composed of two replicative polymerase complexes, one of which synthesizes the leading strand, while the other synthesizes the lagging strand. The replisome is composed of a number of proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase I, RNAse H, and ligase.
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