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Research paper - Harlem Children Society
Research paper - Harlem Children Society

... Working at NYU for the summer and being a part of this project was so great and educational. This project helped me learn a computer language that I have never heard of. I Thank my mentor and co-mentor so much for helping me, being able to write my own programs using python script. I really understa ...
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Replisome



The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized. The net result is formation of two new double stranded DNA sequences that are exact copies of the original double stranded DNA sequence.In terms of structure, the replisome is composed of two replicative polymerase complexes, one of which synthesizes the leading strand, while the other synthesizes the lagging strand. The replisome is composed of a number of proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase I, RNAse H, and ligase.
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