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LIMS for the Masses - University of Alberta
LIMS for the Masses - University of Alberta

... • Metabolomics complements genomics, proteomics and histology • Metabolomics allows probing of rapid physiological changes or events that are not as easily detected by microarrays or histological methods • Canada is actually leading the way (at least for now) in this field ...
LIMS for the Masses
LIMS for the Masses

... • Metabolomics complements genomics, proteomics and histology • Metabolomics allows probing of rapid physiological changes or events that are not as easily detected by microarrays or histological methods • Canada is actually leading the way (at least for now) in this field ...
Spotlight on metabolic remodelling in heart failure
Spotlight on metabolic remodelling in heart failure

... FADH2, as well as GTP. The reducing equivalents then enter the electron transport chain, which is located in the inner mitochondrial membrane. Three of the four complexes pump protons out of the matrix into the intermembrane space, generating a proton gradient across the inner mitochondrial membrane ...
Gluconeogenesis - Assignment Point
Gluconeogenesis - Assignment Point

... cycle can also be used for gluconeogenesis. Amino acids, after their amino group has been removed, feed into parts of the citric acid cycle, and can thus can generate glucose in this pathway. • Fatty acids cannot be turned into glucose, as they are broken down into the two carbon acetyl CoA. (Howeve ...
Mitochondrial Inputs - School of Applied Physiology
Mitochondrial Inputs - School of Applied Physiology

... fructose-bisphosphate aldolase Except for these steps, glycolysis ...
Macromolecules of Life
Macromolecules of Life

... cells are full of individual hemoglobin molecules, each carrying oxygen. ...
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Document

... 9-1 Diprotic Acids and Bases The amino acid building blocks of proteins have the general structure ...
документ
документ

... 5.4.99.5) and a number of other several enzymes are proved to be an active producers of this amino acid (Umbarger, 1978). That is why the best Phe producing strains once selected were the mutants partially or completely dependent on Tyr or Trp for growth. The reports about the other regulative mecha ...
Peptide bond Polypeptide
Peptide bond Polypeptide

... Amino acids join together end-to-end to form a long chain, similarly to glucose molecules. The R groups that they contain do not affect how they bond: it is always in one long chain. A condensation reaction joins the molecules, whereby water is released in the process. The bond formed is a covalent ...
Test yourself
Test yourself

... 3. 4.0 g of sodium, hydroxide is dissolved in water to make up 500 cm 3 of solution. Calculation the molarity of sodium hydroxide solution obtained. [ Relative atomic mass : H,1; Na, 23; O,16] ...
CHEM 1816 Organic Chemistry II - Description
CHEM 1816 Organic Chemistry II - Description

... notify Student Support Services via email at [email protected]. ...
WHAT SHOULD I KNOW ABOUT RESPIRATION NAME ANSWERS
WHAT SHOULD I KNOW ABOUT RESPIRATION NAME ANSWERS

... Pyruvic acid + NADH lactic acid + NAD+ alcoholic fermentation - no oxygen present pyruvic acid + NADH alcohol + CO2 + NAD+ Why do cells use fermentation? (Hint: It’s NOT to make alcohol or lactic acid) To regenerate NAD+ carriers so glycolysis can continue Which pathways require oxygen and which DON ...
chapt 3 The Molecules of Cells
chapt 3 The Molecules of Cells

... – carbonyl group—a carbon linked by a double bond to an oxygen atom, – carboxyl group—consists of a carbon double-bonded to both an oxygen and a hydroxyl group, – amino group—composed of a nitrogen bonded to two hydrogen atoms and the carbon skeleton, and – phosphate group—consists of a phosphorus a ...
Cellular Respiration
Cellular Respiration

... What Happens? = If oxygen IS available, fermentation does NOT happen. 1. Pyruvic Acid is converted into Acetyl CoA. 2. This joins with oxaloacetic acid to form citric acid. 3. Citric Acid goes through a cycle where CO2 and electron carriers are formed. 4. The 2 original pyruvic acid molecules are co ...
c) acidic amino acids
c) acidic amino acids

... lysine, to form a Schiff base linkage to PLP. The active site lysine extracts a proton, promoting tautomerization (shift of the double bond), followed by reprotonation with hydrolysis. ...
use cellular respiration
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... • Happens when yeast makes bread dough rise • CO2 bubbles make air spaces in bread ...
Non-Essential Amino Acids
Non-Essential Amino Acids

... Deamination is the removal of an amine group from a molecule. In the body, deamination takes place primarily in the liver, however glutamate is also deaminated in the kidneys. Deamination is the process by which amino acids are broken down if there is an excess of protein intake. . The oxidation pat ...
Phenyl Acetate Preparation ( from Phenol and
Phenyl Acetate Preparation ( from Phenol and

... Ester yields obtained by the method described approximate those obtained from aliphatic alcohols by the equilibrium method and lie only about 10%below those attainable with procedures utilizing azeotropic water removal during formation of the aliphatic esters (4). Employment of molecular sieves to d ...
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... ester; write the balanced chemical equation for the formation of an ester. Draw the condensed structural formulas for the products from acid and base hydrolysis of esters. Give the common names for amines; draw the condensed structural formulas when given their names. Classify amines as primary, sec ...
Metabolic effects of very-low-carbohydrate diets
Metabolic effects of very-low-carbohydrate diets

... sufficient quantities of the enzymes to convert glycolytic intermediates into molecules that can be transported into the mitochondria to supplement citric acid cycle intermediates. Further, the production of acetoacyl CoA, a substrate of ketone body formation, can occur only in the liver and thus do ...
Decreased Complete Oxidation Capacity of Fatty Acid in the Liver of
Decreased Complete Oxidation Capacity of Fatty Acid in the Liver of

... as mentioned above. CPT II is a important enzyme involved in fatty acid activation, and is positively correlated with transfer velocity of acyl-CoA into mitochondria (Hoppel, 1982). HAD is also an important enzyme for the velocity of fatty acid β-oxidation (Murondoti, 2004). OAA is a key metabolite, ...
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Document

...  Thromboxane is a member of the family of lipids known as eicosanoids. The two major thromboxanes are thromboxane A2 and thromboxane B2. The distinguishing feature of thromboxanes is a 6membered ether-containing ring. ...
Biochemical Aspects of Lipid Storage and
Biochemical Aspects of Lipid Storage and

... and glycolipids serve principally as structural components of membranes rather than as energy reserves and will not be discussed further. The structures of lipids of proven or possible significance in energy metabolism are summarized in Table 1. The long-chain fatty acids of animal lipids have predo ...
Feline Attractant, cis,trans-Nepetalactone: Metabolism in
Feline Attractant, cis,trans-Nepetalactone: Metabolism in

... the urine together with small amounts of dihydronepetalactone, unchanged cis,trans-nepetalactone, and several unidentified compounds. No marked physiological or histological eflects were observed when 20 to 80 milligrams of cis,trans-nepetalactone was administered orally. This is the first report on ...
Objectives 7
Objectives 7

... - Energy is stored as glycogen (carbohydrates), protein (amino acids) or triacylglyercols (fatty acids) - The four circulating fuels are glucose (most important), lactate, free fatty acids, and ketone bodies; these provide fuel in response to specific physiological conditions - In fed and early star ...
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Fatty acid synthesis



Fatty acid synthesis is the creation of fatty acids from acetyl-CoA and malonyl-CoA precursors through action of enzymes called fatty acid synthases. It is an important part of the lipogenesis process, which – together with glycolysis – functions to create fats from blood sugar in living organisms.
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